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11.发明公开
公开(公告)号：EP2040840A1
公开(公告)日：2009-04-01
申请号：EP07765075.2
申请日：2007-07-05
发明人： SAROFIM, Emad
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/0275 , B01L3/502723 , B01L7/52 , B01L2200/027 , B01L2200/0684 , B01L2300/044 , B01L2300/0681 , B01L2300/0809 , B01L2300/087 , B01L2400/0487
摘要： The invention refers to a handling kit for analyzing a liquid sample, especially by nucleic acid amplification, comprising a disposable sample holding and processing device (1) dimensioned for use in an apparatus for analyzing a liquid sample, and a sample transfer tip (12) for transferring liquid into the disposable device (1), the disposable device (1) having a sample preparation chamber (10) which has an outlet (9) and an insertion opening (16) which is adapted to receive the sample transfer tip (12), the insertion opening and the sample transfer tip (12) being dimensioned in such a way that inserting the sample transfer tip (12) into an insertion position in the sample preparation chamber (10) causes a tight seal between an outer wall (40) of the sample transfer tip (12) and an inner wall (41) of the sample preparation chamber (10), the disposable device (1) having a vent (31) for venting the sample preparation chamber (10).
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公开(公告)号：EP4459627A1
公开(公告)日：2024-11-06
申请号：EP24172940.9
申请日：2024-04-29
发明人： GLAUSER, Michael , GUTMANN, Oliver , JANNER, Gabriele Piero , SAROFIM, Emad , THOMANN, Marcel , VOLLENWEIDER, Urs , SCHWEIGHAUSER, Stephan
IPC分类号： G16H10/40
摘要： A computer-implemented method for optimising an assignment of one or more medical samples to one or more analytical tests to be conducted on those medical samples. The method comprises the steps of: obtaining an initial assignment (100) of the one or more medical samples to the one or more analytical tests; determining a compliance status for the or each medical sample, the compliance status indicating: (i) whether a sample quality metric of the or each medical sample violates an analytical test specification (300) of the medical sample's assigned analytical test(s) in the initial assignment (100) and/or (ii) whether the or each medical sample is unprocessable; and performing a mitigation action if one or more compliance status indicate: (i) that the sample quality metric of a given medical sample violates the analytical test specification (300) and/or (ii) a given medical sample is unprocessable.
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公开(公告)号：EP3520893A1
公开(公告)日：2019-08-07
申请号：EP18154962.7
申请日：2018-02-02
摘要： The present disclosure relates to a system for the thermally controlled processing of biological material in a liquid sample in a multiwell plate using magnetic particles. Also disclosed is a corresponding method for the thermally controlled processing of biological material in a liquid sample.
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14.发明授权
公开(公告)号：EP2040840B1
公开(公告)日：2012-03-07
申请号：EP07765075.2
申请日：2007-07-05
发明人： SAROFIM, Emad
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/0275 , B01L3/502723 , B01L7/52 , B01L2200/027 , B01L2200/0684 , B01L2300/044 , B01L2300/0681 , B01L2300/0809 , B01L2300/087 , B01L2400/0487
摘要： The invention refers to a handling kit for analyzing a liquid sample, especially by nucleic acid amplification, comprising a disposable sample holding and processing device (1) dimensioned for use in an apparatus for analyzing a liquid sample, and a sample transfer tip (12) for transferring liquid into the disposable device (1), the disposable device (1) having a sample preparation chamber (10) which has an outlet (9) and an insertion opening (16) which is adapted to receive the sample transfer tip (12), the insertion opening and the sample transfer tip (12) being dimensioned in such a way that inserting the sample transfer tip (12) into an insertion position in the sample preparation chamber (10) causes a tight seal between an outer wall (40) of the sample transfer tip (12) and an inner wall (41) of the sample preparation chamber (10), the disposable device (1) having a vent (31) for venting the sample preparation chamber (10).
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15.发明公开
公开(公告)号：EP2040839A1
公开(公告)日：2009-04-01
申请号：EP07765073.7
申请日：2007-07-05
发明人： SAROFIM, Emad
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/0275 , B01L3/502707 , B01L7/52 , B01L2200/027 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/087
摘要： The invention refers to a disposable sample holding and processing device (1) dimensioned for use in an apparatus for analyzing a liquid sample by nucleic acid amplification, especially the polymerase chain reaction technique, comprising a device body (2) having a structured surface and a sealing cover (4) which covers the structured surface thereby forming a wall of an amplification chamber (5) for performing nucleic acid amplification, and a wall of an inlet channel (6) connected to the amplification chamber (5) for providing the amplification chamber (5) with liquid. According to the invention the device body (2) comprises a sheet (20) on which the structured surface forming the inlet channel (6) is arranged, and that, the sheet (20) carries at least one rib for increasing the stiffness of the device body (2).
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公开(公告)号：EP3404396B1
公开(公告)日：2019-12-18
申请号：EP17000846.0
申请日：2017-05-17
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公开(公告)号：EP3404396A1
公开(公告)日：2018-11-21
申请号：EP17000846.0
申请日：2017-05-17
摘要： A system (1; 1') for processing at least one substrate (2) containing a dried fluid sample (21) is provided, the system (1; 1') comprising a support (12) configured to position the substrate (2), a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31), a container holder (4; 4') configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4') being arranged below the substrate (2), and an extraction subsystem (6) for extracting fume and/or dust generated when laser cutting the substrate (2), wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between. Furthermore, a method for automated processing at least one substrate (2) containing a dried fluid (21) sample by means of such a system (1; 1') is provided.
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公开(公告)号：EP3174970A1
公开(公告)日：2017-06-07
申请号：EP15756564.9
申请日：2015-07-29
发明人： CHERUBINI, Claudio , KOPP, Martin , MILICEVIC, Nenad , MÜLLER, Daniel , SAROFIM, Emad , SAVATIC, Goran
CPC分类号： G01N1/4077 , B01L3/5021 , B01L2300/0848 , B01L2300/0858 , B01L2300/168 , B01L2400/086 , B04B5/0407 , B04B7/08 , B04B11/04 , B04B13/00 , C12M47/02 , G01N1/405 , G01N15/042 , G01N35/00584 , G01N35/10 , G01N2001/4083 , G01N2015/045
摘要： A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion comprising a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion comprising a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion comprising a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
摘要翻译： 本发明涉及一种用于处理液体生物样品中所含颗粒的方法，该方法使用可旋转容器来处理液体生物样品中所含的颗粒，其中可旋转容器具有容器可旋转的纵轴，上部 包括用于接收包含颗粒的液体的顶部开口，用于在可旋转容器搁置时保持液体的下部部分，下部部分包括底部和位于上部部分和下部部分之间的中间部分，中间部分 包括用于在可旋转容器旋转时保持液体的横向收集室。 该方法采用专用的加速和减速曲线来沉淀和重新悬浮感兴趣的颗粒。
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19.发明授权A METHOD AND A DEVICE FOR MEASURING THE SPATIALLY AVERAGED INTENSITY OF A LIGHT BEAM AND A METHOD AND A DEVICE FOR REGULATING A LIGHT SOURCE 有权用于测量A上的强度的方法和设备空间平均BEAM，方法和设备的控制光源
公开(公告)号：EP1240484B1
公开(公告)日：2003-05-28
申请号：EP00991611.5
申请日：2000-12-19
CPC分类号： G01J1/4228 , G01J1/04 , G01J1/0429 , G01J1/1626 , G01J1/32 , G01J1/4257
摘要： A photoelectric module (1) comprises an electrically non-conducting support (2) and a photoelectric element including an array of spatially distributed photoelectric members applied to a surface of the support (2). High simplicity and efficiency is obtained by the double function of module (1) for light transmission or reflection, and spatially averaged light measurement. In a preferred application of module (1) a light source (8, LED) is energized by a driving circuit (9) controlled by an electronic circuit (11). The input of this circuit (11) is connected to the photoelectric module (1), the power delivered to the light source (8) and the intensity of the light beam emitted by the light source being regulated preferably to a constant value by the feedback loop consisting of module (1), electronic circuit (11) and driving circuit (9).
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20.发明公开A METHOD AND A DEVICE FOR MEASURING THE SPATIALLY AVERAGED INTENSITY OF A LIGHT BEAM AND A METHOD AND A DEVICE FOR REGULATING A LIGHT SOURCE 有权用于测量A上的强度的方法和设备空间平均BEAM，方法和设备的控制光源
公开(公告)号：EP1240484A1
公开(公告)日：2002-09-18
申请号：EP00991611.5
申请日：2000-12-19
CPC分类号： G01J1/4228 , G01J1/04 , G01J1/0429 , G01J1/1626 , G01J1/32 , G01J1/4257
摘要： A photoelectric module (1) comprises an electrically non-conducting support (2) and a photoelectric element including an array of spatially distributed photoelectric members applied to a surface of the support (2). High simplicity and efficiency is obtained by the double function of module (1) for light transmission or reflection, and spatially averaged light measurement. In a preferred application of module (1) a light source (8, LED) is energized by a driving circuit (9) controlled by an electronic circuit (11). The input of this circuit (11) is connected to the photoelectric module (1), the power delivered to the light source (8) and the intensity of the light beam emitted by the light source being regulated preferably to a constant value by the feedback loop consisting of module (1), electronic circuit (11) and driving circuit (9).
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