公开(公告)号：EP4429824A1

公开(公告)日：2024-09-18

申请号：EP22834668.0

申请日：2022-11-04

申请人： GILSON SAS

发明人： DUDEK, Bruno ,  GUICHARDON, Stéphane ,  MALVOISIN, Hervé

IPC分类号： B01L3/02

CPC分类号： B01L3/0206 ,  B01L3/022 ,  B01L3/0224 ,  B01L3/0275 ,  B01L3/0286 ,  B01L2200/02520130101 ,  B01L3/0279

公开(公告)号：EP4406655A3

公开(公告)日：2024-08-21

申请号：EP24160866.0

申请日：2020-06-22

申请人： Eppendorf SE

发明人： Kunsch, Matthias ,  Wilth, Marc ,  Tuchscherer, Dana ,  Tesch, Florian ,  Reichmuth, Burghardt

IPC分类号： B01L3/02 ,  G01N35/10

CPC分类号： B01L3/0217 ,  B01L3/0275 ,  B01L3/0282 ,  G01N35/10 ,  B01L2200/08720130101 ,  G01N35/1011

摘要： Pipette für den Gebrauch mit einer einen Kolben und einen Zylinder aufweisenden Pipettenspitze oder Spritze umfassend
• ein stielförmiges Pipettengehäuse,
• eine erste Halteeinrichtung am unteren Ende des Pipettengehäuses zum lösbaren Halten des Zylinders,
• eine im Pipettengehäuse angeordnete Hubstange mit einer zweiten Halteeinrichtung am unteren Ende zum lösbaren Halten des oberen Endes einer Kolbenstange des Kolbens und Verlagern eines Dichtbereichs des Kolbens in einem Kolbenlaufbereich oberhalb einer Spitzenöffnung am unteren Ende des Zylinders,
• ein vom Pipettengehäuse nach außen vorstehendes, relativ zum Pipettengehäuse in axialer Richtung der Hubstange verlagerbares Bedienelement und
• ein im Pipettengehäuse angeordnetes Getriebe mit einem durch das Bedienelement angetriebenen Antrieb und einem die Hubstange antreibenden Abtrieb,
• wobei der Abtrieb eine mehrstufige Zahnstange mit mehreren parallelen Zahnreihen mit unterschiedlicher oder gleicher Höhe, eine fest mit der Hubstange verbundene weitere Zahnstange und zwei drehfest mit einer gemeinsamen Welle verbundene Ritzel mit gleichen oder unterschiedlichen Durchmessern umfasst, wobei das eine der beiden Ritzel mit den Zähnen einer Zahnreihe der mehrstufigen Zahnstange und das andere der beiden Ritzel mit den Zähnen der weiteren Zahnstange kämmt.

公开(公告)号：EP3731954B1

公开(公告)日：2024-07-31

申请号：EP18895659.3

申请日：2018-12-27

IPC分类号： G01N35/10 ,  B01L3/02

CPC分类号： B01L3/0293 ,  B01L3/0275 ,  B01L2200/14620130101 ,  G01N35/1016

公开(公告)号：EP3408025A1

公开(公告)日：2018-12-05

申请号：EP17701136.8

申请日：2017-01-24

申请人： Albert-Ludwigs-Universität Freiburg

发明人： SCHERAG, Frank Daniel ,  RÜHE, Jürgen ,  BRANDSTETTER, Thomas

IPC分类号： B01L3/00 ,  B01L3/02 ,  G01N35/10

CPC分类号： B01L3/5027 ,  B01L3/0275 ,  B01L3/502707 ,  B01L2200/0621 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0832 ,  B01L2300/0838 ,  B01L2300/087 ,  B01L2300/161 ,  B01L2400/0409 ,  B01L2400/049 ,  B01L2400/088

摘要： Embodiments of the present invention provide a tube which has a region that tapers in the direction of an end of the tube; an opening at the end of the tube for receiving a sample material; and a microfluidic structure which is arranged inside the tube in the tapering region thereof and which is connected to the opening, wherein the microfluidic structure is formed so as to carry out a multi-stage bioanalytical reaction with the sample material.

公开(公告)号：EP3183061B1

公开(公告)日：2018-12-05

申请号：EP15756773.6

申请日：2015-08-20

申请人： Corning Incorporated

发明人： CADOTTE, JR John Claude ,  KEENAN, Michael Patrick ,  KENNEY, David Alan ,  RAMMOHAN, Aravind Raghavan ,  WALL, Joseph Christopher ,  WANG, Jin

IPC分类号： B01L3/02

CPC分类号： B01L3/0275 ,  B01L2200/12 ,  B01L2300/0832 ,  B01L2300/0848 ,  B01L2300/12 ,  B29C45/27 ,  B29K2023/12 ,  B29K2995/0097 ,  B29L2023/22

摘要： A pipette tip includes a proximal end having an aperture and a proximal body region having a first internal cavity that receives a pipette member, and a distal end having an aperture and a distal body region having a second internal cavity that in operation receives and discharges a liquid aspirated by the pipette member, where the ratio of the proximal half weight of the pipette tip to the distal half weight of the pipette tip normalized to the total weight of the pipette tip has a value, defined as a thinning constant, wherein the pipette tip has a wall thickness of less than 0.022 inches over the distal region.

公开(公告)号：EP3074131B1

公开(公告)日：2018-11-14

申请号：EP14843227.1

申请日：2014-11-25

申请人： Gencell Biosystems Ltd.

发明人： BARRETT, Brian ,  MCGUIRE, David ,  ROEVEN, Robert

IPC分类号： B01L3/00 ,  B01L3/02 ,  B01L7/00 ,  C12Q1/686 ,  G01N35/10

CPC分类号： B01L3/527 ,  B01L3/0275 ,  B01L3/50855 ,  B01L7/52 ,  B01L2200/0673 ,  B01L2200/14 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0627 ,  B01L2300/0672 ,  B01L2300/0838 ,  B01L2300/18 ,  B01L2300/1894 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N35/1009

摘要： A single-use cartridge, wherein the cartridge defines a plurality of blind bores, each blind bore defining one opening at least one of the plurality of blind bores containing two mutually immiscible liquids, both of which are immiscible with water, one of the two mutually immiscible liquids having a specific gravity greater than water and the other of the two mutually immiscible liquids having a specific gravity less than water.

公开(公告)号：EP3319730A1

公开(公告)日：2018-05-16

申请号：EP16738725.7

申请日：2016-07-08

申请人： Hamilton Bonaduz AG

发明人： SCHWAIGER, Ingo ,  ROMER, Hanspeter

IPC分类号： B01L3/02

CPC分类号： B01L3/0275 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2300/123

摘要： The invention relates to a pipetting device (10) comprising a coupling formation (16) for detachably coupling a pipetting tip (70) to same, and comprising a pipetting channel (12) for changing a pressure in a pipetting tip (70) coupled to the coupling formation (16), said channel extending along a channel path (K) and passing through the coupling formation (16), wherein the coupling formation (16) is formed in such a way that a pipetting tip (70) can be pushed on and taken off said formation along a coupling path (C) which is preferably collinear with the channel path (K). The coupling formation (16) has a coupling deformation assembly having a deformation component (18) and surrounding the pipetting channel (12), which deformation component can be deformed between a locking position and a release position for locking and unlocking a pipetting tip (70) on the coupling formation (16), wherein a radially outer lateral surface section (18c) of a bulge section (18c) of the deformation component (18) - which bulge section is positioned between longitudinal ends (18a, 8b) of the deformation component (18) provided along the coupling path (C) at a distance from one another - is positioned, in the locking position, radially further outwards in relation to the coupling path (C) than in the release position. According to the invention, at least in the locking position, a wall thickness (w) of the bulge section (18c) of the deformation component (18) is smaller than the dimension of the deformation component (18) along the coupling path (C).

公开(公告)号：EP3147670A4

公开(公告)日：2018-04-25

申请号：EP14892855

申请日：2014-05-19

申请人： SYSTEM INSTRUMENTS CO LTD ,  UNIV HIROSAKI ,  NATIONAL UNIV CORPORATION KOBE UNIV

发明人： HAMADA KAZUYUKI ,  AKIBA TAKESHI ,  OHYAMA CHIKARA ,  YONEYAMA TOHRU ,  TOBISAWA YUKI ,  TAKEUCHI TOSHIFUMI

IPC分类号： G01N35/10 ,  B01L9/00 ,  G01N21/03 ,  G01N21/59 ,  G01N21/64 ,  G01N33/53

CPC分类号： G01N33/54386 ,  B01L3/0275 ,  B01L2300/0609 ,  C12Y304/21077 ,  G01N21/0303 ,  G01N21/59 ,  G01N21/6428 ,  G01N33/573 ,  G01N35/00 ,  G01N35/00029 ,  G01N35/1011 ,  G01N2021/6439 ,  G01N2035/1062 ,  G01N2201/068 ,  G01N2333/96455

摘要： An automatic analyzing apparatus 10 includes a chip rack 11 that stores a pipette chip, a pipette 12 into which a specimen is injected, a conveyance unit that conveys the pipette 12 by parallel translation, a reagent rack 14, a reaction unit 15, a detection unit 16, and a detection block unit 17. The pipette chip stored by the chip rack 11 has a planar structure to directly and optically detect the specimen. The chip rack 11 includes, in a hole that receives the pipette chip, a guide corresponding to the structure of the pipette chip. The pipette 12 sucks or discharges the specimen via the pipette chip mounted onto the tip thereof by a drive of a pump. In the detection unit 16, a measurement is carried out with the pipette chip arranged so that the plane that receives light is vertical to an optical axis.

公开(公告)号：EP2515121A4

公开(公告)日：2018-04-04

申请号：EP10837485

申请日：2010-12-08

申请人： HITACHI HIGH TECH CORP

发明人： UEMATSU CHIHIRO ,  MAESHIMA MUNEO

IPC分类号： B01L3/02 ,  C12M1/00 ,  C12N15/09 ,  G01N35/10

CPC分类号： G01N35/10 ,  B01L3/0275 ,  B01L2200/0647 ,  B01L2200/143 ,  B01L2300/0829 ,  B01L2400/043 ,  G01N35/0098 ,  G01N2035/1048 ,  Y10T436/25

摘要： This invention concerns a sample processing device capable of efficiently recovering biological molecules, such as nucleic acids or proteins. The sample processing device is capable of placing a reaction container having a plurality of reaction sites, and it comprises a nozzle mechanism with a nozzle capable of attaching and removing a dispenser tip for dispensing a solution into the reaction sites of the reaction container and a magnetic tip for generating a magnetic field that allows magnetic beads to migrate to a space among the plurality of reaction sites in the reaction container, and a drive control unit controlling the nozzle mechanism.

公开(公告)号：EP3271472A1

公开(公告)日：2018-01-24

申请号：EP16716972.1

申请日：2016-03-18

申请人： 3M Innovative Properties Company

发明人： JAEGER, Jobst Tilman ,  SMITH, Jeffrey D. ,  WISCHNEPOLSKI, Waleri ,  REUTER, Henning ,  BOMMARITO, Giuseppe Marco ,  KSHIRSAGAR, Manjiri T. ,  LEHMAN, Scott D. ,  STAMM, Edward I. Jr. ,  ZILLIGEN, Guenter M.

IPC分类号： C12Q1/04 ,  C12Q1/22 ,  B01D15/00 ,  B01L3/00 ,  C08J9/00 ,  G01N33/543

CPC分类号： C12Q1/22 ,  B01L3/0275 ,  B01L3/5029 ,  B01L2200/028 ,  B01L2200/0684 ,  B01L2300/0681 ,  B01L2300/123 ,  B01L2400/0478 ,  B01L2400/0605 ,  C12Q1/04 ,  G01N33/54386

摘要： Devices for detecting microorganism strains or target cellular analytes are provided. The device includes a filter holder, the filter holder comprising a tip portion; a nonwoven article disposed on the tip portion of the filter holder; and an adaptor attacked to the filter holder, the adaptor defining an aperture. Methods of detecting microorganisms and/or cellular analytes in a fluid sample using the devices are also provided. The method includes obtaining the device; placing a lumened or cannulated device in fluid communication with the device; and passing a fluid sample suspected of containing at least one microorganism strain or target cellular analyte from the lumened or cannulated device through the device and contacting the nonwoven article. The method further includes contacting the nonwoven article with at least one detection reagent and detecting the presence of the at least one microorganism strain or target cellular analyte concentrated by the nonwoven article. Kits and systems including the devices are also provided.