公开(公告)号：EP2317873A1

公开(公告)日：2011-05-11

申请号：EP09800919.4

申请日：2009-07-22

申请人： GENERAL MILLS, INC.

发明人： VAN LENGERICH, Bernhard, H. ,  WALTHER, Goeran

IPC分类号： A23L1/05 ,  A23L1/30

CPC分类号： A23L33/12 ,  A23L7/117 ,  A23L7/17 ,  A23L19/09 ,  A23L29/20 ,  A23P30/20 ,  A23V2002/00 ,  A23V2200/02 ,  A23V2200/224 ,  A23V2200/242 ,  A23V2200/244 ,  A23V2250/032 ,  A23V2250/186 ,  A23V2250/5072 ,  A23V2250/51 ,  A23V2250/5108 ,  A23V2250/5118 ,  A23V2250/628 ,  A23V2250/6406 ,  A23V2250/642 ,  A23V2250/70

摘要： A fruit product containing a readily oxidizable polyunsaturated fatty acid, such as omega-3 fatty acids, may be prepared by cooking a fruit base composition to obtain a cooked fruit base composition, cooling the cooked fruit base composition, admixing the fruit base composition with an oil which contains at least one readily oxidizable polyunsaturated fatty acid. Additionally, an acidic antioxidant for preventing oxidation of the at least one polyunsaturated fatty acid; and at least one polyol for providing mobility for the acidic antioxidant is admixed with the cooked fruit base composition to obtain an at least substantially homogeneous mixture, which may be formed into pieces.

公开(公告)号：EP1119345B1

公开(公告)日：2009-04-29

申请号：EP99951433.4

申请日：1999-10-06

申请人： GENERAL MILLS, INC.

发明人： VAN LENGERICH, Bernhard, H.

IPC分类号： A21D13/00 ,  A23L1/00 ,  A23L1/03 ,  A21D13/08 ,  A23L1/164 ,  A23L1/22 ,  A61K9/00 ,  A61K9/16

CPC分类号： A23L27/72 ,  A21D13/28 ,  A23C2220/204 ,  A23L7/135 ,  A23L9/10 ,  A23L29/065 ,  A23P10/25 ,  A23P10/30 ,  A61K9/0056 ,  Y02A50/387 ,  Y02A50/465 ,  Y02A50/469 ,  Y02A50/471

摘要： A liquid encapsulant component which contains an active, sensitive encapsulant, such as a live microorganism or an enzyme dissolved or dispersed in a liquid plasticizer is admixed with a plasticizable matrix material. The matrix material is plasticizable by the liquid plasticizer and the encapsulation of the active encapsulant is accomplished at a low temperature and under low shear conditions. The active component is encapsulated and/or embedded in the plasticizable matrix component or material in a continuous process to produce discrete, solid particles. The liquid content of the liquid encapsulant component provides substantially all or completely all of the liquid plasticizer needed to plasticize the matrix component to obtain a formable, extrudable, cuttable, mixture or dough. Removal of liquid plasticizer prior to extrusion is not needed to adjust the viscosity of the mixture for formability. Release of an active component from the matrix may be delayed or controlled over time so that the active component is delivered when and where it is needed to perform its intended function. Controlled release, discrete, solid particles which contain an encapsulated and/or embedded component such as a heat sensitive or readily oxidizable pharmaceutically, biologically, or nutritionally active component are continuously produced without substantial destruction of the matrix material or encapsulant.

摘要翻译： 含有溶解或分散在液体增塑剂中的活性敏感包封剂（例如活微生物或酶）的液体包封剂组分与可塑性基质材料混合。 基质材料可通过液体增塑剂塑化，并且活性密封剂的封装在低温和低剪切条件下完成。 活性组分被封装和/或嵌入可塑化基体组分或材料中以连续过程产生不连续的固体颗粒。 液体密封剂组分的液体含量提供基本上全部或完全全部增塑基质组分所需的液体增塑剂，以获得可成形的，可挤出的，可切割的，混合物或面团。 在挤出之前除去液体增塑剂不需要调节混合物的可成形性的粘度。 从矩阵中释放有源组件可能会随着时间的推移而被延迟或控制，以便在需要执行其预期功能的时间和地点交付有源组件。 包含包封和/或嵌入组分的控制释放的不连续的固体颗粒，如热敏或易于氧化的药学，生物学或营养学活性组分连续生产而基本上不破坏基质材料或包封剂。

公开(公告)号：EP1218498B1

公开(公告)日：2009-03-18

申请号：EP00954113.7

申请日：2000-08-17

申请人： GENERAL MILLS, INC.

发明人： VAN LENGERICH, Bernhard, H.

IPC分类号： C12N11/10 ,  B01J13/02

CPC分类号： B01J13/02 ,  B01J13/04 ,  C12N9/96 ,  C12N11/10

摘要： A solid active, sensitive encapsulant component is admixed with at least one plasticizable matrix material, a matrix component which is substantially non-plasticizable at temperatures lower than the decomposition temperature of the encapsulant and which increases the rate of release of the encapsulant from the matrix, and a liquid plasticizer, to obtain a formable, extrudable, cuttable mixture or dough.

公开(公告)号：EP1119345A1

公开(公告)日：2001-08-01

申请号：EP99951433.4

申请日：1999-10-06

申请人： GENERAL MILLS, INC.

发明人： VAN LENGERICH, Bernhard, H.

IPC分类号： A61K9/10

CPC分类号： A23L27/72 ,  A21D13/28 ,  A23C2220/204 ,  A23L7/135 ,  A23L9/10 ,  A23L29/065 ,  A23P10/25 ,  A23P10/30 ,  A61K9/0056 ,  Y02A50/387 ,  Y02A50/465 ,  Y02A50/469 ,  Y02A50/471

摘要： A liquid encapsulant component which contains an active, sensitive encapsulant, such as a live microorganism or an enzyme dissolved or dispersed in a liquid plasticizer is admixed with a plasticizable matrix material. The matrix material is plasticizable by the liquid plasticizer and the encapsulation of the active encapsulant is accomplished at a low temperature and under low shear conditions. The active component is encapsulated and/or embedded in the plasticizable matrix component or material in a continuous process to produce discrete, solid particles. The liquid content of the liquid encapsulant component provides substantially all or completely all of the liquid plasticizer needed to plasticize the matrix component to obtain a formable, extrudable, cuttable, mixture or dough. Removal of liquid plasticizer prior to extrusion is not needed to adjust the viscosity of the mixture for formability. Release of an active component from the matrix may be delayed or controlled over time so that the active component is delivered when and where it is needed to perform its intended function. Controlled release, discrete, solid particles which contain an encapsulated and/or embedded component such as a heat sensitive or readily oxidizable pharmaceutically, biologically, or nutritionally active component are continuously produced without substantial destruction of the matrix material or encapsulant.

摘要翻译： 其含有活性，敏感密封剂，求作为活微生物或酶在液体增塑剂溶解或分散的液体密封剂组分的溶液与可塑化基质材料。 的基质材料是由液体增塑剂和活性密封剂的封装，在低温和低剪切条件下被完成的塑化。 活性组分被包封和/或嵌入在塑化的基质组分或材料在连续工艺中，以产生离散的，固体颗粒。 所述液体包封剂组分的液体内容提供了基本上所有或完全呼叫的所有增塑基体组分，以获得可成形的，可挤出，可切割，混合物或面团所需要的液体增塑剂。 不需要在挤出前液体增塑剂的除去来调节可成型性的混合物的粘度。 从基质中的活性成分的释放可以被延迟或受控随时间所以没有活性组分被递送并当在需要的地方，以执行其预期功能。 控制释放的，离散的固体，将其在包封和/或嵌入部件包含颗粒：如热敏感或易氧化药学，生物学，或营养活性成分被连续无基质材料或密封剂的实质破坏产生。