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11.发明公开
公开(公告)号：EP4301516A1
公开(公告)日：2024-01-10
申请号：EP22763940.8
申请日：2022-03-02
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公开(公告)号：EP4220137A1
公开(公告)日：2023-08-02
申请号：EP22207460.1
申请日：2014-12-09
申请人： Illumina, Inc.
摘要： Biosensor comprising a flow cell and a detection device having the flow cell coupled thereto, the flow cell and the detection device forming a flow channel that is configured to have biological or chemical substances therein that generate light emissions in response to an excitation light, the detection device including a device base having a sensor array of light sensors and a guide array of light guides, the light guides configured to receive the excitation light and the light emissions from the flow channel, each of the light guides extending into the device base along a central longitudinal axis from an input region of the light guide toward a corresponding light sensor of the sensor array, the light guides including a filter material that is configured to filter the excitation light and permit the light emissions to propagate therethrough toward the corresponding light sensors, the device base including device circuitry that is electrically coupled to the light sensors and configured to transmit data signals based on photons detected by the light sensors; wherein the device base includes peripheral crosstalk shields located therein that at least partially surround corresponding light guides of the guide array, the crosstalk shields at least partially surrounding the corresponding light guides about the respective longitudinal axis to reduce optical crosstalk between adjacent light sensors.
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公开(公告)号：EP4139053A1
公开(公告)日：2023-03-01
申请号：EP21828202.8
申请日：2021-05-24
申请人： Illumina Inc
发明人： BECKMAN, Travis , CRIVELLI, Paul , COX-MURANAMI, Wesley , FOLEY, Jennifer , SEGALE, Darren , DUCHNAK, Allison , FRANKIE, Keith , MAR, Cameron
IPC分类号： B01L3/00
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公开(公告)号：EP3912724A1
公开(公告)日：2021-11-24
申请号：EP21180636.9
申请日：2019-05-01
申请人： Illumina, Inc.
发明人： DELATTRE, Cyril , RHEE, Minsoung , LIU, Jeffrey , COX-MURANAMI, Wesley , CRIVELLI, Paul , FOLEY, Jennifer , SEGALE, Darren , TAYLOR, Jay , HAGE, Matthew , PAIK, Philip , ALLEGOREN, Erik , HERTZOG, David , MOROZ-SMIETANA, Alex , MA, Xiaoxiao , TAKAHASHI, Tsukasa , WESTERBERG, Brandon
摘要： An instrument includes a reagent management system. The reagent management system includes a plurality of reagent wells, each reagent well operable to contain a reagent of a plurality of reagents positioned therein. The reagent management system is operable to select a flow of reagent from one of the plurality of reagents. A flexible connection includes a laminate stack and includes a first flexible channel in fluid communication with the reagent management system. The first flexible channel is operable to route the flow of reagent therethrough. A flow cell includes a flow channel in fluid communication with the first flexible channel. The flow channel is operable to route the flow of reagent over analytes positioned in the flow channel. The flexible connection enables the flow cell to be moved by the instrument relative to a fixed reference point in the instrument.
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15.发明公开
公开(公告)号：EP3870704A1
公开(公告)日：2021-09-01
申请号：EP19876740.2
申请日：2019-10-23
申请人： Illumina, Inc.
发明人： BERTI, Lorenzo , BLACK, Fiona E. , BRODIN, Jeffrey Dennis , FISHER, Jeffrey , LEONG, Siew Hong , SEGALE, Darren
IPC分类号： C12N15/10 , C12Q1/6827 , C12Q1/6869
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公开(公告)号：EP3628025A1
公开(公告)日：2020-04-01
申请号：EP19802686.6
申请日：2019-05-01
申请人： Illumina Inc.
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公开(公告)号：EP3606673A1
公开(公告)日：2020-02-12
申请号：EP18781368.8
申请日：2018-04-02
申请人： Illumina, Inc.
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