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公开(公告)号：EP3788383A1
公开(公告)日：2021-03-10
申请号：EP19796285.5
申请日：2019-04-30
申请人： Illumina Inc.
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公开(公告)号：EP4453519A1
公开(公告)日：2024-10-30
申请号：EP22912683.4
申请日：2022-12-21
申请人： Illumina, Inc.
发明人： CAO, Zhenning , FOLEY, Jennifer , DELATTRE, Cyril , PATEL, Maulik , MAR, Cameron
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公开(公告)号：EP4408584A1
公开(公告)日：2024-08-07
申请号：EP22877295.0
申请日：2022-09-29
申请人： ILLUMINA, INC.
发明人： DREWS, Bradley , SEGALE, Darren , FOLEY, Jennifer , TWOMEY, Jack
IPC分类号： B01L3/00
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4.发明公开
公开(公告)号：EP4301516A1
公开(公告)日：2024-01-10
申请号：EP22763940.8
申请日：2022-03-02
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公开(公告)号：EP4139053A1
公开(公告)日：2023-03-01
申请号：EP21828202.8
申请日：2021-05-24
申请人： Illumina Inc
发明人： BECKMAN, Travis , CRIVELLI, Paul , COX-MURANAMI, Wesley , FOLEY, Jennifer , SEGALE, Darren , DUCHNAK, Allison , FRANKIE, Keith , MAR, Cameron
IPC分类号： B01L3/00
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公开(公告)号：EP3912724A1
公开(公告)日：2021-11-24
申请号：EP21180636.9
申请日：2019-05-01
申请人： Illumina, Inc.
发明人： DELATTRE, Cyril , RHEE, Minsoung , LIU, Jeffrey , COX-MURANAMI, Wesley , CRIVELLI, Paul , FOLEY, Jennifer , SEGALE, Darren , TAYLOR, Jay , HAGE, Matthew , PAIK, Philip , ALLEGOREN, Erik , HERTZOG, David , MOROZ-SMIETANA, Alex , MA, Xiaoxiao , TAKAHASHI, Tsukasa , WESTERBERG, Brandon
摘要： An instrument includes a reagent management system. The reagent management system includes a plurality of reagent wells, each reagent well operable to contain a reagent of a plurality of reagents positioned therein. The reagent management system is operable to select a flow of reagent from one of the plurality of reagents. A flexible connection includes a laminate stack and includes a first flexible channel in fluid communication with the reagent management system. The first flexible channel is operable to route the flow of reagent therethrough. A flow cell includes a flow channel in fluid communication with the first flexible channel. The flow channel is operable to route the flow of reagent over analytes positioned in the flow channel. The flexible connection enables the flow cell to be moved by the instrument relative to a fixed reference point in the instrument.
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公开(公告)号：EP3628025A1
公开(公告)日：2020-04-01
申请号：EP19802686.6
申请日：2019-05-01
申请人： Illumina Inc.
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公开(公告)号：EP3038834B1
公开(公告)日：2018-12-12
申请号：EP14767207.5
申请日：2014-08-29
发明人： JAMSHIDI, Arash , LIN, Yan-You , ARAVANIS, Alex , DELATTRE, Cyril , RIVAL, Arnaud , FOLEY, Jennifer , SABOUNCHI, Poorya , KHURANA, Tarun , BABAZADEH, Majid , AMINI, Hamed , VENKATESAN, Bala Murali , BOWEN, M. Shane , BARNARD, Steven M. , ROGERT BACIGALUPO, Maria Candelaria , DEHLINGER, Dietrich
IPC分类号： B41J2/04
CPC分类号： B01L3/50273 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/502792 , B01L2200/06 , B01L2300/0636 , B01L2300/0819 , B01L2300/0858 , B01L2300/087 , B01L2300/161 , B01L2300/166 , B01L2400/0427 , B41J2/04 , G01N15/1463 , G01N15/1475 , G01N2015/1006
摘要： Provided herein is a droplet actuator including (a) first and second substrates separated by a droplet-operations gap, the first and second substrates including respective hydrophobic surfaces that face the droplet-operations gap; (b) a plurality of electrodes coupled to at least one of the first substrate and the second substrate, the electrodes arranged along the droplet-operations gap to control movement of a droplet along the hydrophobic surfaces within the droplet-operations gap; and (c) a hydrophilic or variegated-hydrophilic surface exposed to the droplet-operations gap, the hydrophilic or variegated-hydrophilic surface being positioned to contact the droplet when the droplet is at a select position within the droplet-operations gap.
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9.发明公开MANIPULATION OF DROPLETS ON HYDROPHILIC OR VARIEGATED-HYDROPHILIC SURFACES 审中-公开操作VONTRÖPFCHENAUF HYDROPHILEN ODER VARIEGIERT HYDROPHILENOBERFLÄCHEN
公开(公告)号：EP3038834A1
公开(公告)日：2016-07-06
申请号：EP14767207.5
申请日：2014-08-29
发明人： JAMSHIDI, Arash , LIN, Yan-You , ARAVANIS, Alex , DELATTRE, Cyril , RIVAL, Arnaud , FOLEY, Jennifer , SABOUNCHI, Poorya , KHURANA, Tarun , BABAZADEH, Majid , AMINI, Hamed , VENKATESAN, Bala Murali , BOWEN, M. Shane , BARNARD, Steven M. , ROGERT BACIGALUPO, Maria Candelaria , DEHLINGER, Dietrich
IPC分类号： B41J2/04
CPC分类号： B01L3/50273 , B01F13/0071 , B01F13/0076 , B01F13/0084 , B01L3/502792 , B01L2200/06 , B01L2300/0636 , B01L2300/0819 , B01L2300/0858 , B01L2300/087 , B01L2300/161 , B01L2300/166 , B01L2400/0427 , B41J2/04 , G01N15/1463 , G01N15/1475 , G01N2015/1006
摘要： Provided herein is a droplet actuator including (a) first and second substrates separated by a droplet-operations gap, the first and second substrates including respective hydrophobic surfaces that face the droplet-operations gap; (b) a plurality of electrodes coupled to at least one of the first substrate and the second substrate, the electrodes arranged along the droplet-operations gap to control movement of a droplet along the hydrophobic surfaces within the droplet-operations gap; and (c) a hydrophilic or variegated-hydrophilic surface exposed to the droplet-operations gap, the hydrophilic or variegated-hydrophilic surface being positioned to contact the droplet when the droplet is at a select position within the droplet-operations gap.
摘要翻译： 本文提供的液滴致动器包括（a）由液滴操作间隙分开的第一和第二基板，第一和第二基板包括面对液滴操作间隙的各个疏水表面; （b）耦合到所述第一基板和所述第二基板中的至少一个的多个电极，所述电极沿着所述液滴操作间隙布置以控制液滴沿着所述液滴操作间隙内的疏水表面的运动; 和（c）暴露于液滴操作间隙的亲水或杂色亲水表面，当液滴在液滴操作间隙内的选择位置时，亲水或杂色亲水表面定位成接触液滴。
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