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33 条记录 (耗时 0.017 秒)

    Medical adhesive sheet and production thereof
    11.
    发明公开
    Medical adhesive sheet and production thereof 失效
    Medizinische Selbstklebefolie und Verfahren zu deren Herstellung

    公开(公告)号：EP0891782A2

    公开(公告)日：1999-01-20

    申请号：EP98113131.1

    申请日：1998-07-15

    申请人： NITTO DENKO CORPORATION

    发明人： Inosaka, Keigo ,  Muraoka, Takateru ,  Akemi, Hitoshi ,  Otsuka, Saburo ,  Inoue, Yuichi

    IPC分类号： A61L15/58

    CPC分类号： A61L15/58

    摘要： A medical adhesive sheet comprising a support and an adhesive layer formed on one side of said support, wherein the adhesive layer comprises an adhesive polymer having a weight average molecular weight of not less than 2,000,000, preferably not less than 2,500,000, and at least one plasticizer compatible with said polymer. The medical adhesive sheet of the present invention simultaneously satisfies the adhesive property to the skin and low irritation property, since it can retain the plasticizer in the adhesive layer, even without a crosslinking treatment. The effects of the present invention can be exerted irrespective of the kind of functional group that the plasticizer and drug have.

    摘要翻译： 一种医用胶粘片，其特征在于，在所述支持体的一面形成有支撑体和粘合剂层，其中所述粘合剂层包含重均分子量不小于2,000,000，优选不低于2,500,000的粘合剂聚合物，以及至少一种增塑剂 与所述聚合物相容。 本发明的医用粘合片同时满足与皮肤的粘合性和低刺激性，因为即使不进行交联处理也能够将增塑剂保持在粘合剂层中。 不管增塑剂和药物具有的官能团的种类如何，都可以发挥本发明的效果。

    Patch preparation
    14.
    发明公开
    Patch preparation 审中-公开
    Pflasterherstellung

    公开(公告)号：EP2052718A1

    公开(公告)日：2009-04-29

    申请号：EP08253376.1

    申请日：2008-10-17

    申请人： Nitto Denko Corporation

    发明人： Inosaka, Keigo ,  Tamura, Kei ,  Yoshino, Osamu

    IPC分类号： A61K9/70 ,  A61K47/10 ,  A61K47/32

    CPC分类号： A61K9/7053 ,  A61K47/10 ,  A61K47/32

    摘要： The present invention aims at provision of a patch preparation having a small area and permitting adhesion for a long time.
    The present invention provides a patch preparation having an adhesive layer on at least one surface of a support, wherein the adhesive layer contains an adhesive, a poorly soluble drug, a first organic liquid component, a second organic liquid component, a third organic liquid component and crosslinked polyvinylpyrrolidone, the solubility of the poorly soluble drug in the first organic liquid component is not less than the solubility of the poorly soluble drug in the second organic liquid component, and the solubility of the poorly soluble drug in the second organic liquid component is not less than the solubility of the poorly soluble drug in the third organic liquid component.

    摘要翻译： 本发明的目的在于提供具有小面积并且允许长时间粘合的贴片制剂。 本发明提供了一种在支撑体的至少一个表面上具有粘合剂层的贴片制剂，其中所述粘合剂层包含粘合剂，难溶性药物，第一有机液体组分，第二有机液体组分，第三有机液体组分 和交联聚乙烯吡咯烷酮时，难溶性药物在第一有机液体成分中的溶解度不低于第二有机液体成分中难溶性药物的溶解度，并且难溶性药物在第二有机液体成分中的溶解度为 不低于难溶性药物在第三有机液体组分中的溶解度。

    Stabilized percutaneous absorption preparation
    16.
    发明公开
    Stabilized percutaneous absorption preparation 有权
    Stabilisierte Zusammensetzungen zur perkutan吸收

    公开(公告)号：EP0904778A1

    公开(公告)日：1999-03-31

    申请号：EP98116798.4

    申请日：1998-09-04

    申请人： NITTO DENKO CORPORATION

    发明人： Muraoka, Takateru ,  Akemi, Hitoshi ,  Inosaka, Keigo ,  Ishitani, Hiroko ,  Otsuka, Saburo

    IPC分类号： A61K9/70 ,  A61K47/14 ,  A61K47/22

    CPC分类号： A61K9/7053 ,  A61K9/0014 ,  A61K9/7061 ,  A61K47/14 ,  A61K47/22

    摘要： The present invention provides a percutaneous absorption preparation which hardly causes the coloration phenomenon and is excellent in the stability of the drug content. The percutaneous absorption preparation comprises a support and a pressure-sensitive adhesive layer formed on at least one side of the support, wherein the pressure-sensitive adhesive layer contains a percutaneous absorptive drug and at least one of 2-mercaptobenzimidazole and propyl gallate, with the proviso that the percutaneous absorptive drug is not 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole and pharmacologically acceptable salt thereof.

    摘要翻译： 本发明提供一种几乎不引起着色现象并且药物含量稳定性优异的经皮吸收制剂。 经皮吸收制剂包括在支持体的至少一侧上形成的载体和压敏粘合剂层，其中该压敏粘合剂层含有经皮吸收药物和2-巯基苯并咪唑和没食子酸丙酯中的至少一种，其中 条件是经皮吸收药物不是6-氨基-5-氯-1-异丙基-2-（4-甲基-1-哌嗪基）苯并咪唑及其药理学上可接受的盐。

    Drug containing adhesive preparation
    19.
    发明公开
    Drug containing adhesive preparation 有权
    Herstellung von Fentanyl-haltigen Klebstoffen

    公开(公告)号：EP1970079A2

    公开(公告)日：2008-09-17

    申请号：EP08250660.1

    申请日：2008-02-27

    申请人： Nitto Denko Corporation

    发明人： Nishimura, Masato ,  Terashi, Sachiko ,  Satoda, Shiro ,  Inosaka, Keigo ,  Matsuoka, Kensuke

    IPC分类号： A61L15/58 ,  A61L24/00 ,  A61L24/04

    CPC分类号： A61L24/0015 ,  A61L15/58 ,  A61L24/04 ,  A61L2300/402

    摘要： The present invention aims at providing an adhesive preparation wherein a drug is sufficiently dissolved in an adhesive layer and is not easily separated from the adhesive layer even during preservation of the adhesive preparation.
    The present invention provides an adhesive preparation having an adhesive layer on at least one surface of a support, wherein the adhesive layer comprises a first synthetic rubber having a viscosity average molecular weight of 1,600,000 - 6,500,000, a drug, an organic liquid component and a tackifier. The present invention further provides the aforementioned adhesive preparation, wherein the organic liquid component is contained in the adhesive layer in a proportion of 20 wt% or above relative to the total weight of the adhesive layer.

    摘要翻译： 本发明的目的在于提供一种粘合剂，其中药物充分地溶解在粘合剂层中，并且即使在粘合剂制备过程中也不容易与粘合剂层分离。 本发明提供一种在支撑体的至少一个表面上具有粘合剂层的粘合剂制剂，其中粘合剂层包括粘均分子量为1,600,000至6,500,000的第一合成橡胶，药物，有机液体组分和增粘剂 。 本发明还提供了上述粘合剂制剂，其中粘合剂层中的有机液体组分相对于粘合剂层的总重量为20重量％以上。