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9 条记录 (耗时 0.011 秒)

    Nicotine-containing patch preparation
    1.
    发明公开
    Nicotine-containing patch preparation 审中-公开
    含尼古丁贴剂制剂

    公开(公告)号：EP2505194A2

    公开(公告)日：2012-10-03

    申请号：EP12161080.2

    申请日：2012-03-23

    申请人： Nitto Denko Corporation

    发明人： Enomoto, Kazumi ,  Kuroda, Hidetoshi ,  Satoda, Shiro ,  Nakamura, Koji ,  Takita, Tomohito

    IPC分类号： A61K9/70 ,  A61K47/10 ,  A61K47/14 ,  A61K47/22 ,  A61K31/465

    CPC分类号： A61K9/7053 ,  A61K9/7061 ,  A61K31/465

    摘要： An object of the present invention is to provide a nicotine-containing patch preparation which enables to suppress degradation of nicotine and coloring of the patch preparation. The present invention provides a patch preparation comprising a support and an adhesive layer on its at least one surface, wherein the adhesive layer comprises an adhesive polymer, nicotine and a stabilizer, and the stabilizer is at least one kind selected from the group consisting of butylhydroxyanisole (BHA), propyl gallate (PGA), dibutylhydroxytoluene (BHT) and 2-mercaptobenzimidazole (MBT).

    摘要翻译： 本发明的目的是提供一种含尼古丁贴剂制剂，其能够抑制尼古丁的降解和贴剂制剂的着色。 本发明提供一种贴剂制剂，其包含载体和在其至少一个表面上的粘合剂层，其中所述粘合剂层包含粘合剂聚合物，尼古丁和稳定剂，并且所述稳定剂为选自以下的至少一种：丁基羟基茴香醚 （BHA），没食子酸丙酯（PGA），二丁基羟基甲苯（BHT）和2-巯基苯并咪唑（MBT）。

    Patch and patch preparation
    2.
    发明公开
    Patch and patch preparation 审中-公开
    Flicken und Flickenherstellung

    公开(公告)号：EP2494995A2

    公开(公告)日：2012-09-05

    申请号：EP12153805.2

    申请日：2012-02-03

    申请人： Nitto Denko Corporation

    发明人： Hashino, Ryo ,  Kuroda, Hidetoshi ,  Ameyama, Satoshi ,  Satoda, Shiro ,  Ishikura, Jun

    IPC分类号： A61L15/44 ,  A61K9/70

    CPC分类号： A61L15/58 ,  A61K9/7061 ,  A61L15/44 ,  Y10T428/2887 ,  Y10T428/2891 ,  C08L33/10

    摘要： A patch according to an embodiment of the present invention includes a support and a pressure-sensitive adhesive layer provided on at least one surface of the support. The pressure-sensitive adhesive layer contains an acrylic copolymer obtained by copolymerizing a monomer mixture containing (a) a (meth)acrylic acid alkyl ester, (b) a hydroxyl group-containing monomer, and (c) a diketone group-containing monomer.

    摘要翻译： 根据本发明的实施方式的贴片包括支撑体和设置在支撑体的至少一个表面上的压敏粘合剂层。 压敏粘合剂层含有通过共聚含有（a）（甲基）丙烯酸烷基酯，（b）含羟基单体和（c）含二酮基团的单体）的单体混合物而获得的丙烯酸共聚物。

    Nicotine transdermal preparation and production method thereof
    4.
    发明公开
    Nicotine transdermal preparation and production method thereof 有权
    Nikotinhaltiges transdermales therapeutisches系统和dessen Herstellung

    公开(公告)号：EP1774964A1

    公开(公告)日：2007-04-18

    申请号：EP06255234.4

    申请日：2006-10-11

    申请人： NITTO DENKO CORPORATION

    发明人： Satoda, Shiro ,  Ninomiya, Kazuhisa ,  Saito, Junichi ,  Matsuoka, Kensuke ,  Kikuchi, Shunetsu

    IPC分类号： A61K9/70 ,  A61K31/465

    CPC分类号： A61K9/7061 ,  A61K31/465 ,  A61K47/14

    摘要： The present invention provides a production method of a nicotine transdermal preparation, which is capable of producing a nicotine transdermal preparation conveniently and economically, while maintaining highly precise content uniformity, which is capable of producing a preparation simultaneously achieving fixedness and a soft feeling during adhesion, associated with reduced skin irritation upon peeling off and superior in adhesive property.

    摘要翻译： 本发明提供了一种尼古丁透皮制剂的制造方法，其能够方便，经济地制造尼古丁透皮制剂，同时保持高精度的含量均匀性，能够同时制备粘合时的固定性和柔软感， 与剥离时的皮肤刺激性降低，粘合性优异。

    Drug containing adhesive preparation
    6.
    发明公开
    Drug containing adhesive preparation 有权
    含有药物的粘合剂的制备

    公开(公告)号：EP1970079A3

    公开(公告)日：2009-06-17

    申请号：EP08250660.1

    申请日：2008-02-27

    申请人： Nitto Denko Corporation

    发明人： Nishimura, Masato ,  Terashi, Sachiko ,  Satoda, Shiro ,  Inosaka, Keigo ,  Matsuoka, Kensuke

    IPC分类号： A61L15/58 ,  A61L24/00 ,  A61L24/04

    CPC分类号： A61L24/0015 ,  A61L15/58 ,  A61L24/04 ,  A61L2300/402

    摘要： The present invention aims at providing an adhesive preparation wherein a drug is sufficiently dissolved in an adhesive layer and is not easily separated from the adhesive layer even during preservation of the adhesive preparation.
    The present invention provides an adhesive preparation having an adhesive layer on at least one surface of a support, wherein the adhesive layer comprises a first synthetic rubber having a viscosity average molecular weight of 1,600,000 - 6,500,000, a drug, an organic liquid component and a tackifier. The present invention further provides the aforementioned adhesive preparation, wherein the organic liquid component is contained in the adhesive layer in a proportion of 20 wt% or above relative to the total weight of the adhesive layer.

    Patch and patch preparation
    7.
    发明公开
    Patch and patch preparation 审中-公开
    补丁和补丁的准备

    公开(公告)号：EP2494995A3

    公开(公告)日：2012-09-26

    申请号：EP12153805.2

    申请日：2012-02-03

    申请人： Nitto Denko Corporation

    发明人： Hashino, Ryo ,  Kuroda, Hidetoshi ,  Ameyama, Satoshi ,  Satoda, Shiro ,  Ishikura, Jun

    IPC分类号： A61L15/44 ,  A61K9/70 ,  A61L15/58

    CPC分类号： A61L15/58 ,  A61K9/7061 ,  A61L15/44 ,  Y10T428/2887 ,  Y10T428/2891 ,  C08L33/10

    摘要： A patch according to an embodiment of the present invention includes a support and a pressure-sensitive adhesive layer provided on at least one surface of the support. The pressure-sensitive adhesive layer contains an acrylic copolymer obtained by copolymerizing a monomer mixture containing (a) a (meth)acrylic acid alkyl ester, (b) a hydroxyl group-containing monomer, and (c) a diketone group-containing monomer.

    摘要翻译： 根据本发明的一个实施例的贴片包括支撑件和设置在支撑件的至少一个表面上的压敏粘合剂层。 该压敏粘合剂层包含通过共聚包含（a）（甲基）丙烯酸烷基酯，（b）含羟基单体和（c）含二酮基单体的单体混合物获得的丙烯酸共聚物。

    Drug containing adhesive preparation
    9.
    发明公开
    Drug containing adhesive preparation 有权
    Herstellung von Fentanyl-haltigen Klebstoffen

    公开(公告)号：EP1970079A2

    公开(公告)日：2008-09-17

    申请号：EP08250660.1

    申请日：2008-02-27

    申请人： Nitto Denko Corporation

    发明人： Nishimura, Masato ,  Terashi, Sachiko ,  Satoda, Shiro ,  Inosaka, Keigo ,  Matsuoka, Kensuke

    IPC分类号： A61L15/58 ,  A61L24/00 ,  A61L24/04

    CPC分类号： A61L24/0015 ,  A61L15/58 ,  A61L24/04 ,  A61L2300/402

    摘要： The present invention aims at providing an adhesive preparation wherein a drug is sufficiently dissolved in an adhesive layer and is not easily separated from the adhesive layer even during preservation of the adhesive preparation.
    The present invention provides an adhesive preparation having an adhesive layer on at least one surface of a support, wherein the adhesive layer comprises a first synthetic rubber having a viscosity average molecular weight of 1,600,000 - 6,500,000, a drug, an organic liquid component and a tackifier. The present invention further provides the aforementioned adhesive preparation, wherein the organic liquid component is contained in the adhesive layer in a proportion of 20 wt% or above relative to the total weight of the adhesive layer.

    摘要翻译： 本发明的目的在于提供一种粘合剂，其中药物充分地溶解在粘合剂层中，并且即使在粘合剂制备过程中也不容易与粘合剂层分离。 本发明提供一种在支撑体的至少一个表面上具有粘合剂层的粘合剂制剂，其中粘合剂层包括粘均分子量为1,600,000至6,500,000的第一合成橡胶，药物，有机液体组分和增粘剂 。 本发明还提供了上述粘合剂制剂，其中粘合剂层中的有机液体组分相对于粘合剂层的总重量为20重量％以上。