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公开(公告)号：EP2371354B1
公开(公告)日：2014-01-22
申请号：EP11002555.8
申请日：2011-03-28
CPC分类号： A61K9/7007 , A61K8/0241 , A61K9/0056
摘要： The present invention provides a film-form preparation having a rapid dissolution profile in the mouth and sufficient film strength, and also having excellent appearance and feel. More specifically, the present invention provides a film-form preparation including: a water-soluble and a polar organic solvent-soluble edible polymer; and polar organic solvent-insoluble drug particles.
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12.发明公开Edible jelly-form composition, jelly-form preparation and method for producing jelly-form preparation 审中-公开成果冻形式的可食用组合物，在制备果冻形式，并产生在一个果冻形式的制备方法
公开(公告)号：EP2524687A2
公开(公告)日：2012-11-21
申请号：EP12003916.9
申请日：2012-05-18
CPC分类号： A61K9/006 , A61K9/0056 , A61K47/10 , A61K47/36 , A61K47/42
摘要： The present invention aims to provide a jelly (as a result, easy-to-swallow), intraorally soluble edible jelly composition although it is preferably free of water. The present invention relates to an edible jelly composition including: a gelling agent; and a nonvolatile organic solvent compatible with the gelling agent.
摘要翻译： 本发明旨在提供一个果冻（其结果，易于吞咽的）口腔内溶解可食果冻组合物虽然是优选不含水。 本发明涉及到在食用果冻组合物包括：凝胶剂; 并与胶凝剂相容的非挥发性有机溶剂。
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13.发明公开Film-form preparation and method for producing the same 审中-公开Filmbildungspräparat和Verfahren zu dessen Herstellung
公开(公告)号：EP2371358A1
公开(公告)日：2011-10-05
申请号：EP11002556.6
申请日：2011-03-28
IPC分类号： A61K9/70 , A61K31/192 , A61K31/4045 , A61K31/405
CPC分类号： A61K9/7007 , A61K9/0056 , A61K31/192 , A61K31/4045 , A61K31/405
摘要： The present invention provides a film-form preparation having a rapid dissolution profile in the mouth and sufficient film strength, and also having excellent appearance and feel. More specifically, the present invention provides a film-form preparation including: a water-soluble edible polymer; and water-insoluble drug particles, wherein an average particle size of the drug particles is 0.1 to 60 µm.
摘要翻译： 本发明提供了一种在口中具有快速溶出曲线并具有足够的膜强度并且还具有优异外观和手感的膜形式。 更具体地说，本发明提供一种膜状制剂，包括：水溶性可食用聚合物; 和水不溶性药物粒子，其中药物粒子的平均粒径为0.1〜60μm。
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14.发明公开E75-vaccine composition for transdermal administration 审中-公开E75-enthaltende Impfstoffzusammensetzung zur transdermalen Verabreichung
公开(公告)号：EP2762158A1
公开(公告)日：2014-08-06
申请号：EP14000323.7
申请日：2014-01-29
发明人： Okubo, Katsuyuki , Maeda, Yoshiki , Shishido, Takuya , Asari, Daisuke , Okazaki, Arimichi , Matsushita, Kyohei , LI, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/0005 , A61K39/0011 , A61K2039/54
摘要： The invention provides a cancer vaccine composition for transdermal administration for inducing cellular immunity comprising (i) HER2/neu E75 peptide and/or a modified HER2/neu E75 peptide; and (ii) a first cellular immunity induction promoter.
摘要翻译： 本发明提供用于诱导细胞免疫的透皮给药的癌症疫苗组合物，其包含（i）HER2 / neu E75肽和/或经修饰的HER2 / neu E75肽; 和（ii）第一细胞免疫诱导启动子。
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15.发明公开
公开(公告)号：EP2762154A2
公开(公告)日：2014-08-06
申请号：EP14000319.5
申请日：2014-01-29
发明人： Shishido, Takuya , Okubo, Katsuyuki , Asari, Daisuke , Okazaki, Arimichi , Maeda, Yoshiki , Matsushita, Kyohei , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/12 , A61K9/0014 , A61K9/06 , A61K9/7084 , A61K39/0011 , A61K39/39 , A61K47/32 , A61K47/34 , A61K2039/54 , A61K2039/55583
摘要： Disclosed is a vaccine composition for transdermal administration to induce cellular immunity, comprising an antigen, wherein Th1 cell ratio in a model animal for immunological evaluation that received the composition is 10% or more.
摘要翻译： 公开了一种用于透皮给药以诱导细胞免疫的疫苗组合物，其包含抗原，其中接受组合物的用于免疫评估的模型动物中的Th1细胞比率为10％以上。
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16.发明公开Jelly-form preparation and method for producing jelly-form preparation 有权Geleeformzubereitung und Verfahren zur Erzeugung der Geleeformzubereitung
公开(公告)号：EP2545904A1
公开(公告)日：2013-01-16
申请号：EP12005125.5
申请日：2012-07-11
CPC分类号： A61K9/0056 , A61K9/006 , A61K47/42
摘要： Provided is a jelly preparation which enables easy intraoral dissolution thereof, easy adjustment of the dissolution time, and stable containment of a drug therein. The jelly preparation of the present invention is a jelly preparation including water, a gelatin, a drug, and a trivalent metal ion.
摘要翻译： 本发明提供能够容易地口内溶解，容易调节溶解时间，以及药物稳定容纳的果冻制剂。 本发明的果冻制剂是包含水，明胶，药物和三价金属离子的果冻制剂。
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17.发明公开Edible jelly-form composition, jelly-form preparation and method for producing jelly-form preparation 审中-公开成果冻形式的可食用组合物，在制备果冻形式，并产生在一个果冻形式的制备方法
公开(公告)号：EP2524687A3
公开(公告)日：2012-12-12
申请号：EP12003916.9
申请日：2012-05-18
CPC分类号： A61K9/006 , A61K9/0056 , A61K47/10 , A61K47/36 , A61K47/42
摘要： The present invention aims to provide a jelly (as a result, easy-to-swallow), intraorally soluble edible jelly composition although it is preferably free of water. The present invention relates to an edible jelly composition including: a gelling agent; and a nonvolatile organic solvent compatible with the gelling agent.
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公开(公告)号：EP2371354A1
公开(公告)日：2011-10-05
申请号：EP11002555.8
申请日：2011-03-28
CPC分类号： A61K9/7007 , A61K8/0241 , A61K9/0056
摘要： The present invention provides a film-form preparation having a rapid dissolution profile in the mouth and sufficient film strength, and also having excellent appearance and feel. More specifically, the present invention provides a film-form preparation including: a water-soluble and a polar organic solvent-soluble edible polymer; and polar organic solvent-insoluble drug particles.
摘要翻译： 本发明提供一种在口中具有快速溶出特性和足够的膜强度并且还具有优异的外观和手感的膜形式制剂。 更具体地说，本发明提供了一种薄膜状制剂，其包含：水溶性和极性有机溶剂可溶性可食用聚合物; 和极性有机溶剂不溶性药物颗粒。
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19.发明公开Stabilized pharmaceutical composition, liquid preparation of stabilized pharmaceutical composition, film-form preparation, and method for producing film-form preparation 审中-公开一种稳定化药物组合物，稳定化药物组合物，成膜制备的液体制剂，及其制造方法的成膜准备
公开(公告)号：EP2371353A1
公开(公告)日：2011-10-05
申请号：EP11002554.1
申请日：2011-03-28
CPC分类号： A61K9/0056 , A61K9/006 , A61K9/0095 , A61K9/7007 , A61K39/35 , A61K39/36
摘要： The present invention provides a stabilized pharmaceutical composition that enables the production of a preparation for desensitization therapy useful as an agent for the prevention or treatment of allergic diseases such as pollen hypersensitivity, has outstanding allergen protein stability, and is useful for storage and transfer.
More specifically, the present invention provides a stabilized pharmaceutical composition containing an allergen protein and at least one type of stabilizer selected from the group consisting of sugars, sugar alcohols, and sugar fatty acids.摘要翻译： 本发明提供一种稳定化药物组合物确实能生产用于脱敏治疗的过敏性疾病的预防或治疗剂有用的制剂：如花粉过敏症，具有优异的变应原蛋白的稳定性，并且是用于存储和传送是有用的。 更具体地，本发明提供含有变应原蛋白质和选自由糖，糖醇和糖脂肪酸中的至少一种类型的稳定剂的稳定化的药物组合物。
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20.发明公开E75-vaccine composition for mucosal administration 审中-公开E75-enthaltende Impfstoffzusammensetzung zur mukosalen Verabreichung
公开(公告)号：EP2762161A1
公开(公告)日：2014-08-06
申请号：EP14000326.0
申请日：2014-01-29
发明人： Asari, Daisuke , Okazaki, Arimichi , Matsushita, Kyohei , Okubo, Katsuyuki , Maeda, Yoshiki , Shishido, Takuya , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/39 , A61K39/0011 , A61K2039/541 , A61K2039/542
摘要： The present invention provides a cancer vaccine composition for mucosal administration comprising (i) a HER2/neu E75 peptide and/or a modified HER2/neu E75 peptide; and (ii) a first cellular immunity induction promoter.
摘要翻译： 本发明提供了一种用于粘膜给药的癌症疫苗组合物，其包含（i）HER2 / neu E75肽和/或经修饰的HER2 / neu E75肽; 和（ii）第一细胞免疫诱导启动子。
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