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1.发明公开E75-vaccine composition for mucosal administration 审中-公开E75-enthaltende Impfstoffzusammensetzung zur mukosalen Verabreichung
公开(公告)号：EP2762161A1
公开(公告)日：2014-08-06
申请号：EP14000326.0
申请日：2014-01-29
发明人： Asari, Daisuke , Okazaki, Arimichi , Matsushita, Kyohei , Okubo, Katsuyuki , Maeda, Yoshiki , Shishido, Takuya , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/39 , A61K39/0011 , A61K2039/541 , A61K2039/542
摘要： The present invention provides a cancer vaccine composition for mucosal administration comprising (i) a HER2/neu E75 peptide and/or a modified HER2/neu E75 peptide; and (ii) a first cellular immunity induction promoter.
摘要翻译： 本发明提供了一种用于粘膜给药的癌症疫苗组合物，其包含（i）HER2 / neu E75肽和/或经修饰的HER2 / neu E75肽; 和（ii）第一细胞免疫诱导启动子。
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公开(公告)号：EP2762155A3
公开(公告)日：2015-11-04
申请号：EP14000320.3
申请日：2014-01-29
发明人： Asari, Daisuke , Okubo, Katsuyuki , Shishido, Takuya , Okazaki, Arimichi , Maeda, Yoshiki , Matsushita, Kyohei , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K9/0014 , A61K31/192 , A61K31/196 , A61K31/216 , A61K31/353 , A61K31/4035 , A61K31/405 , A61K31/407 , A61K31/415 , A61K31/42 , A61K31/426 , A61K31/5575 , A61K31/616 , A61K38/10 , A61K39/0011 , A61K39/39 , A61K2039/54 , A61K2039/572
摘要： The invention provides a vaccine composition containing an antigen for inducing cellular immunity, comprising at least one first cellular immunity induction promoter.
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公开(公告)号：EP2762155A2
公开(公告)日：2014-08-06
申请号：EP14000320.3
申请日：2014-01-29
发明人： Asari, Daisuke , Okubo, Katsuyuki , Shishido, Takuya , Okazaki, Arimichi , Maeda, Yoshiki , Matsushita, Kyohei , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K9/0014 , A61K31/192 , A61K31/196 , A61K31/216 , A61K31/353 , A61K31/4035 , A61K31/405 , A61K31/407 , A61K31/415 , A61K31/42 , A61K31/426 , A61K31/5575 , A61K31/616 , A61K38/10 , A61K39/0011 , A61K39/39 , A61K2039/54 , A61K2039/572
摘要： The invention provides a vaccine composition containing an antigen for inducing cellular immunity, comprising at least one first cellular immunity induction promoter.
摘要翻译： 本发明提供含有用于诱导细胞免疫的抗原的疫苗组合物，其包含至少一种第一细胞免疫诱导启动子。
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公开(公告)号：EP2762153A3
公开(公告)日：2015-04-01
申请号：EP14000318.7
申请日：2014-01-29
发明人： Okazaki, Arimichi , Matsushita, Kyohei , Asari, Daisuke , Shishido, Takuya , Maeda, Yoshiki , Okubo, Katsuyuki , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/0011 , A61K39/39 , A61K2039/542 , A61K2039/55511 , A61K2039/55516 , A61K2039/55561 , A61K2039/55566 , A61K2039/55583 , A61K2039/572
摘要： The present invention provides a vaccine composition which comprises a cellular immunity induction promoter universally usable against various antigens in cellular immunity induction by mucosal administration of the antigen and exerts a high cellular immunity inducing effect by mucosal administration. The present invention provides a vaccine composition for mucosal administration to induce cellular immunity, comprising: (i) an antigen; and (ii) one or more cellular immunity induction promoters selected from the group consisting of a TLR ligand, a cyclic dinucleotide, a helper peptide and an immunomodulatory small molecule drug.
摘要翻译： 本发明提供了一种疫苗组合物，其包含通过粘膜施用抗原而在细胞免疫诱导中通常可用于各种抗原的细胞免疫诱导启动子，并通过粘膜施用发挥高细胞免疫诱导作用。 本发明提供一种用于粘膜给药以诱导细胞免疫的疫苗组合物，包括：（i）抗原; 和（ii）选自TLR配体，环状二核苷酸，辅助肽和免疫调节小分子药物的一种或多种细胞免疫诱导启动子。
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公开(公告)号：EP2762153A2
公开(公告)日：2014-08-06
申请号：EP14000318.7
申请日：2014-01-29
发明人： Okazaki, Arimichi , Matsushita, Kyohei , Asari, Daisuke , Shishido, Takuya , Maeda, Yoshiki , Okubo, Katsuyuki , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/0011 , A61K39/39 , A61K2039/542 , A61K2039/55511 , A61K2039/55516 , A61K2039/55561 , A61K2039/55566 , A61K2039/55583 , A61K2039/572
摘要： The present invention provides a vaccine composition which comprises a cellular immunity induction promoter universally usable against various antigens in cellular immunity induction by mucosal administration of the antigen and exerts a high cellular immunity inducing effect by mucosal administration. The present invention provides a vaccine composition for mucosal administration to induce cellular immunity, comprising: (i) an antigen; and (ii) one or more cellular immunity induction promoters selected from the group consisting of a TLR ligand, a cyclic dinucleotide, a helper peptide and an immunomodulatory small molecule drug.
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6.发明公开Edible jelly-form composition, jelly-form preparation and method for producing jelly-form preparation 审中-公开成果冻形式的可食用组合物，在制备果冻形式，并产生在一个果冻形式的制备方法
公开(公告)号：EP2524687A2
公开(公告)日：2012-11-21
申请号：EP12003916.9
申请日：2012-05-18
CPC分类号： A61K9/006 , A61K9/0056 , A61K47/10 , A61K47/36 , A61K47/42
摘要： The present invention aims to provide a jelly (as a result, easy-to-swallow), intraorally soluble edible jelly composition although it is preferably free of water. The present invention relates to an edible jelly composition including: a gelling agent; and a nonvolatile organic solvent compatible with the gelling agent.
摘要翻译： 本发明旨在提供一个果冻（其结果，易于吞咽的）口腔内溶解可食果冻组合物虽然是优选不含水。 本发明涉及到在食用果冻组合物包括：凝胶剂; 并与胶凝剂相容的非挥发性有机溶剂。
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7.发明公开Wt1 peptide cancer vaccine composition for mucosal administration 审中-公开WT1-Peptid-Krebsimpfstoffzusammensetzung zur mukosalen Verabreichung
公开(公告)号：EP2762160A1
公开(公告)日：2014-08-06
申请号：EP14000325.2
申请日：2014-01-29
发明人： Asari, Daisuke , Matsushita, Kyohei , Okazaki, Arimichi , Maeda, Yoshiki , Okubo, Katsuyuki , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/0011 , A61K9/0043 , A61K9/006 , A61K2039/541 , A61K2039/542
摘要： The present invention provides a cancer vaccine composition for mucosal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a cellular immunity induction promoter. The composition efficiently induces cellular immunity against a cancer in a subject.
摘要翻译： 本发明提供用于诱导细胞免疫的粘膜给药用癌症疫苗组合物，其包含（i）WT1肽和/或修饰的WT1肽; 和（ii）细胞免疫诱导启动子。 该组合物有效地诱导受试者中针对癌症的细胞免疫。
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8.发明公开E75-vaccine composition for transdermal administration 审中-公开E75-enthaltende Impfstoffzusammensetzung zur transdermalen Verabreichung
公开(公告)号：EP2762158A1
公开(公告)日：2014-08-06
申请号：EP14000323.7
申请日：2014-01-29
发明人： Okubo, Katsuyuki , Maeda, Yoshiki , Shishido, Takuya , Asari, Daisuke , Okazaki, Arimichi , Matsushita, Kyohei , LI, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/0005 , A61K39/0011 , A61K2039/54
摘要： The invention provides a cancer vaccine composition for transdermal administration for inducing cellular immunity comprising (i) HER2/neu E75 peptide and/or a modified HER2/neu E75 peptide; and (ii) a first cellular immunity induction promoter.
摘要翻译： 本发明提供用于诱导细胞免疫的透皮给药的癌症疫苗组合物，其包含（i）HER2 / neu E75肽和/或经修饰的HER2 / neu E75肽; 和（ii）第一细胞免疫诱导启动子。
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9.发明公开
公开(公告)号：EP2762154A2
公开(公告)日：2014-08-06
申请号：EP14000319.5
申请日：2014-01-29
发明人： Shishido, Takuya , Okubo, Katsuyuki , Asari, Daisuke , Okazaki, Arimichi , Maeda, Yoshiki , Matsushita, Kyohei , Li, Wenjing , Hori, Mitsuhiko , Sugiyama, Haruo
IPC分类号： A61K39/00
CPC分类号： A61K39/12 , A61K9/0014 , A61K9/06 , A61K9/7084 , A61K39/0011 , A61K39/39 , A61K47/32 , A61K47/34 , A61K2039/54 , A61K2039/55583
摘要： Disclosed is a vaccine composition for transdermal administration to induce cellular immunity, comprising an antigen, wherein Th1 cell ratio in a model animal for immunological evaluation that received the composition is 10% or more.
摘要翻译： 公开了一种用于透皮给药以诱导细胞免疫的疫苗组合物，其包含抗原，其中接受组合物的用于免疫评估的模型动物中的Th1细胞比率为10％以上。
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10.发明公开Edible jelly-form composition, jelly-form preparation and method for producing jelly-form preparation 审中-公开成果冻形式的可食用组合物，在制备果冻形式，并产生在一个果冻形式的制备方法
公开(公告)号：EP2524687A3
公开(公告)日：2012-12-12
申请号：EP12003916.9
申请日：2012-05-18
CPC分类号： A61K9/006 , A61K9/0056 , A61K47/10 , A61K47/36 , A61K47/42
摘要： The present invention aims to provide a jelly (as a result, easy-to-swallow), intraorally soluble edible jelly composition although it is preferably free of water. The present invention relates to an edible jelly composition including: a gelling agent; and a nonvolatile organic solvent compatible with the gelling agent.
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