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公开(公告)号：EP2070556A3
公开(公告)日：2011-08-31
申请号：EP08253982.6
申请日：2008-12-12
摘要： The main object of the present invention is to provide a patch package structure including a patch containing a physiologically active ingredient and a package housing the patch, which is capable of stably retaining the physiologically active ingredient in the patch during preservation. This object can be achieved by employing the following constitution.
To be specific, the present invention is a patch package structure including a patch 1 having an adhesive layer containing an organic liquid component, and a packaging member 51 housing the patch, wherein the packaging member 51 includes a first package 11, the first package 11 including an acrylonitrile resin layer 12, a moisture-absorbing layer 13 formed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 formed on the moisture-absorbing layer 13, and the acrylonitrile resin layer 12 is provided on the proximal side of the patch 1.-
公开(公告)号：EP2075013A2
公开(公告)日：2009-07-01
申请号：EP08254000.6
申请日：2008-12-12
CPC分类号： A61F15/001 , A61L15/24 , C08L33/20
摘要： The main object of the present invention is to provide a patch package structure capable of stably retaining the physiologically active ingredient in a patch during preservation of the patch. This object can be achieved by employing the following constitution.
To be specific, the present invention is a patch package structure including a patch 1 and a packaging member 51 holding the patch, wherein the patch 1 includes a support 2 and an adhesive layer 3 formed on at least one surface of the support 2, the packaging member 51 includes a first package 11, the first package 11 including an acrylonitrile resin layer 12, a moisture-absorbing layer 13 formed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 formed on the moisture-absorbing layer 13, and the acrylonitrile resin layer 12 is provided on the proximal side of the patch 1.摘要翻译： 本发明的主要目的是提供一种贴片包装结构，其能够在贴片保存期间将生理活性成分稳定地保留在贴片中。 该目的可以通过采用以下构成来实现。 具体而言，本发明是一种贴片包装结构，其包括贴片1和保持贴片的包装构件51，其中贴片1包括支撑体2和形成在支撑体2的至少一个表面上的粘合剂层3， 包装构件51包括第一包装11，第一包装11包括丙烯腈树脂层12，形成在丙烯腈树脂层12上的吸湿层13和形成在吸湿层13上的不透湿层14，以及 丙烯腈树脂层12设置在贴剂1的基端侧。
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公开(公告)号：EP1716850A1
公开(公告)日：2006-11-02
申请号：EP06007496.0
申请日：2006-04-10
IPC分类号： A61K9/70
CPC分类号： A61K9/7061 , Y10T442/20 , Y10T442/2738 , Y10T442/2754
摘要： The present invention provides an adhesive preparation superior in adhesion property, which does not peel off or fall off easily and which can be adhered for a long time. An adhesive preparation 10 has a support 1 made of a cloth, and a pressure sensitive adhesive layer 3 formed on one surface of the support 1, which contains a pressure sensitive adhesive and a drug. The ratio (CW/AW) of a mass (CW) per unit area of the support 1 and a mass (AW) per unit area of the pressure sensitive adhesive layer 3 is 1.0 - 5.0, an adhesive layer-free surface of the support 1 has a static friction coefficient of 0.25 - 0.75, and a 20% modulus (AM) in one direction of the adhesive preparation 10 and a 20% modulus (EM) in the direction perpendicular to that direction are each 0.5 - 1.5 N/cm, and the ratio thereof (AM/EM) is 0.5 - 2.0.
摘要翻译： 本发明提供粘合性优异的粘合剂制剂，其不会容易地剥离或脱落，并且可以长时间粘合。 粘合剂10具有由布制成的支撑体1和形成在载体1的一个表面上的压敏粘合剂层3，该粘合剂层3含有压敏粘合剂和药物。 支撑体1的每单位面积的质量（CW）的比（CW / AW）和压敏粘合剂层3的每单位面积的质量（AW）为1.0-5.0，载体的无粘合剂层的表面 1具有0.25-0.75的静摩擦系数，粘合剂10的一个方向上的20％模量（AM）和与该方向垂直的方向上的20％模量（EM）分别为0.5-1.5N / cm ，其比例（AM / EM）为0.5-2.0。
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14.发明授权Composition for enhancing transdermal absorption of drug and patch preparation 有权用于增强药物和贴剂制剂透皮吸收的组合物
公开(公告)号：EP2777692B1
公开(公告)日：2018-05-02
申请号：EP14158640.4
申请日：2014-03-10
IPC分类号： A61K9/00
CPC分类号： A61K47/12 , A61K9/0014 , A61K9/7038 , A61K9/7053 , A61K9/7061 , A61K9/7084 , A61K31/138 , A61K31/405 , A61K31/421 , A61K47/10
摘要： The present invention relates to a composition for enhancing transdermal absorption of a drug, containing a polyvalent alcohol having 3 to 8 carbon atoms, an organic acid having 2 to 20 carbon atoms, and a higher alcohol having 12 to 20 carbon atoms, and a patch preparation containing a support and a drug-containing adhesive layer containing the composition on one surface of the support.
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15.发明授权Composition for enhancing transdermal absorption of a drug and patch preparation 有权用于增强药物和贴剂制剂透皮吸收的组合物
公开(公告)号：EP2570116B1
公开(公告)日：2017-10-25
申请号：EP12184301.5
申请日：2012-09-13
CPC分类号： A61K9/7061 , A61K31/41 , A61K31/422
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公开(公告)号：EP2574335B1
公开(公告)日：2016-02-03
申请号：EP12186402.9
申请日：2012-09-27
IPC分类号： A61K9/70
CPC分类号： A61K9/7053 , A61K9/7061
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17.发明公开Composition for enhancing transdermal absorption of a drug and patch preparation 有权Zusammensetzung zur Verbesserung der transdermalen Absorption eines Arzneimittel- undPflasterpräparats
公开(公告)号：EP2570116A1
公开(公告)日：2013-03-20
申请号：EP12184301.5
申请日：2012-09-13
CPC分类号： A61K9/7061 , A61K31/41 , A61K31/422
摘要： The problem of the present invention is to provide a composition for enhancing transdermal absorption of a drug, which shows a sufficiently high enhancing effect on transdermal absorption of an acidic drug.
A composition for enhancing transdermal absorption of an acidic drug, comprising a polyvalent alcohol having 3 - 8 carbon atoms, a higher alcohol having 12 - 20 carbon atoms and an organic amine having 2 - 9 carbon atoms.摘要翻译： 本发明的问题在于提供一种增强药物透皮吸收的组合物，其对酸性药物的经皮吸收具有足够高的增强作用。 一种用于增强酸性药物的透皮吸收的组合物，包括具有3-8个碳原子的多元醇，具有12-20个碳原子的高级醇和具有2-9个碳原子的有机胺。
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公开(公告)号：EP1795188B1
公开(公告)日：2010-03-31
申请号：EP06025475.2
申请日：2006-12-08
发明人： Washiro, Satoko , Hanatani, Akinori
CPC分类号： A61K9/0014 , A61K9/7038
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公开(公告)号：EP2070556A2
公开(公告)日：2009-06-17
申请号：EP08253982.6
申请日：2008-12-12
摘要： The main object of the present invention is to provide a patch package structure including a patch containing a physiologically active ingredient and a package housing the patch, which is capable of stably retaining the physiologically active ingredient in the patch during preservation. This object can be achieved by employing the following constitution.
To be specific, the present invention is a patch package structure including a patch 1 having an adhesive layer containing an organic liquid component, and a packaging member 51 housing the patch, wherein the packaging member 51 includes a first package 11, the first package 11 including an acrylonitrile resin layer 12, a moisture-absorbing layer 13 formed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 formed on the moisture-absorbing layer 13, and the acrylonitrile resin layer 12 is provided on the proximal side of the patch 1.摘要翻译： 本发明的主要目的是提供一种贴剂包装结构，其包含含有生理活性成分的贴剂和容纳所述贴剂的包装，所述包装在保存期间能够稳定地将生理活性成分保持在贴剂中。 该目的可以通过采用以下构成来实现。 具体而言，本发明是一种贴剂包装结构体，其包括具有含有有机液体成分的粘合剂层的贴剂1和容纳贴剂的包装部件51，其中包装部件51包括第一包装11，第一包装11 包括丙烯腈树脂层12，形成在丙烯腈树脂层12上的吸湿层13和形成在吸湿层13上的不透湿层14，丙烯腈树脂层12设置在吸湿层13的近侧 补丁1。
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20.发明公开Preparation for external use comprising an ionic liquid 有权Zusammensetzung zuräusserlichenAnwendung enthaltend eine ionischeFlüssigkeit
公开(公告)号：EP1795188A1
公开(公告)日：2007-06-13
申请号：EP06025475.2
申请日：2006-12-08
发明人： Washiro, Satoko , Hanatani, Akinori
CPC分类号： A61K9/0014 , A61K9/7038
摘要： An external preparation having excellent percutaneous absorption ability for ionic drugs is provided. An external preparation which comprises the following components (a) and (b);
component (a): an ionic drug,
component (b) : an ionic liquid containing a cation and an anion. By this construction, the ionic liquid functions as a solubilizing agent for the ionic drug and thereby the solubility of the drug in the external preparation increases, so that percutaneous absorption ability of the ionic drug is accelerated.摘要翻译： 提供了具有优异的离子药物的经皮吸收能力的外用制剂。 包含以下组分（a）和（b）的外用制剂; 组分（a）：离子药物，组分（b）：含有阳离子和阴离子的离子液体。 通过这种结构，离子液体用作离子药物的增溶剂，从而使外用制剂中的药物的溶解度增加，从而加速离子药物的经皮吸收能力。
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