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公开(公告)号：EP1948618A1
公开(公告)日：2008-07-30
申请号：EP07838458.3
申请日：2007-09-18
IPC分类号： C07D239/42 , A61K31/505 , A61P3/06
CPC分类号： C07D239/42
摘要： Provided is a crystalline form of rosuvastatin calcium characterized by X-ray powder diffraction peaks at about 4.7, 19.4 and 22.3° 2 theta ± 0.2° 2 theta and processes for the preparation thereof.
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公开(公告)号：EP1848724A2
公开(公告)日：2007-10-31
申请号：EP06827338.2
申请日：2006-10-31
发明人： KANSAL, Vinod, Kumar , MISTRY, Dhirenkumar, N. , PANDEY, Saurabh , PATEL, Rakesh , WIZEL, Shlomit
IPC分类号： C07D513/04
CPC分类号： C07D501/00
摘要： The invention relates to processes for preparing cefdinir via its potassium and cesium salts.
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公开(公告)号：EP1503762A2
公开(公告)日：2005-02-09
申请号：EP03750112.9
申请日：2003-05-12
IPC分类号： A61K31/496 , C07D401/04
CPC分类号： C07D215/56
摘要： Provided are novel crystalline forms of gatifloxacin denominated forms A, B, C, D, E1, F, G, H, I, and J, and methods for their preparation. Also provided are methods for making known crystalline forms of hatifloxacin, in particular forms omega and T2RP.
摘要翻译： 提供了加替沙星命名形式A，B，C，D，E1，F，G，H，I和J的新型结晶形式及其制备方法。 还提供了制备已知的hatifloxacin结晶形式的方法，特别是形式为ω-2和T2RP。
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公开(公告)号：EP1482945A1
公开(公告)日：2004-12-08
申请号：EP03721434.3
申请日：2003-03-20
发明人： LIFSHITZ-LIRON, Revital , KOVALEVSKI-ISHAI, Eti , DOLITZKY, Ben-Zion , WIZEL, Shlomit , LIDOR-HADAS, Rami
IPC分类号： A61K31/55 , A61P25/18 , C07D281/16
CPC分类号： C07D281/16
摘要： The present invention relates to novel crystalline forms of quetiapine hemifumarate (I), denominated quetiapine hemifuramate form II and quetiapine hemifuramate form III. These novel crystalline forms of quetiapine hemifuramate have been characterized by methods including x-ray powder diffraction (XRD), Fourier transform IR spectroscopy (FTIR), differential scanning calorimetry (DSC), and thermal gravimetric analysis (TGA). Methods for preparation of the novel crystalline quetiapine hemifuramate form II as its chloroform solvate and its dichloromethane solvate, form III as its chloroform solvate, and form I are provided.
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公开(公告)号：EP2024331A1
公开(公告)日：2009-02-18
申请号：EP07776925.5
申请日：2007-05-08
发明人： ARONHIME, Judith , LINDOR-HADAS, Ramy , NIDDAM-HILDESHEIM, Valerie , WIZEL, Shlomit , LIFSHITZ-LIRON, Revital , PINCHASOV, Michael
IPC分类号： C07D207/34 , C07D405/06 , C07D493/04
CPC分类号： C07D207/34 , C07D405/06 , C07D493/04
摘要： The present invention provides atorvastatin hemi-calcium Form VIII that is stable against the formation of atorvastatin hemi-calcium is atorvastatin calcium epoxy dihydroxy (AED).
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公开(公告)号：EP1943256A2
公开(公告)日：2008-07-16
申请号：EP06827341.6
申请日：2006-10-31
发明人： KANSAL, Vinod, Kumar , MISTRY, Dhirenkumar, N. , PANDEY, Saurabh , PATEL, Rakesh , WIZEL, Shlomit , HILDESHEIM, Jean
IPC分类号： C07D501/00 , A61K31/41 , A61P31/12
CPC分类号： C07D501/22 , C07D501/00
摘要： The present invention encompasses the solid state chemistry of cefdinir potassium salt.
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公开(公告)号：EP1883625A2
公开(公告)日：2008-02-06
申请号：EP06771224.0
申请日：2006-05-23
IPC分类号： C07C271/30 , A61P5/14 , A61K31/137
CPC分类号： C07C211/63 , C07C209/82 , C07C211/30
摘要： Provided is amorphous cinacalcet hydrochloride, processes for the preparation thereof, and pharmaceutical compositions therewith.
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公开(公告)号：EP1805148A2
公开(公告)日：2007-07-11
申请号：EP06801964.5
申请日：2006-08-16
IPC分类号： C07D239/42 , A61P3/06 , A61K31/505
CPC分类号： C07D239/42
摘要： Provided is a crystalline rosuvastatin intermediate and processes for preparation thereof.
摘要翻译： 提供了一种结晶罗苏伐他汀中间体及其制备方法。
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公开(公告)号：EP1451194B1
公开(公告)日：2006-10-04
申请号：EP02776152.7
申请日：2002-10-03
IPC分类号： C07D498/06 , A61K31/5383 , C07D265/00 , C07D221/00
CPC分类号： C07D498/06
摘要： Levofloxacin was prepared by reacting (S)-(-)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid with N-methyl piperazine in a polar solvent or in a neat mixture to form levofloxacin. Further processing of the levofloxacin produced novel levofloxacin forms, including a hemihydrate and Forms A, B, C, F, G and H.
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公开(公告)号：EP1656339A1
公开(公告)日：2006-05-17
申请号：EP05748381.0
申请日：2005-05-09
发明人： WIZEL, Shlomit , FRENKEL, Gustavo , GOME, Boaz
IPC分类号： C07C231/24 , C07C233/63 , A61K31/16 , A61P3/00
CPC分类号： C07C231/24 , A61K31/198 , C07C233/63 , C07C2601/14
摘要： Provided are crystalline forms of nateglinide and processes for their preparation.
摘要翻译： 提供那格列奈的结晶形式及其制备方法。
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