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公开(公告)号：EP4379391A1
公开(公告)日：2024-06-05
申请号：EP23212901.5
申请日：2023-11-29
申请人： Shimadzu Corporation
发明人： TANAKA, Hiroto
IPC分类号： G01N35/00
CPC分类号： G01N2035/009120130101 , G01N35/00722 , G01N2035/0034620130101
摘要： An analysis apparatus according to this invention includes a measurer configured to measure a sample; a temperature adjuster configured to adjust a temperature of the sample during measurement; a display configured to display information: and a controller configured to control a function of displaying an interface on the display as the information, wherein the interface includes the followings: a plurality of items including temperature and time, and a graphic schematic diagram representing a thermal cycle with time and visualizing the plurality of items on the thermal cycle.
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公开(公告)号：EP4378947A1
公开(公告)日：2024-06-05
申请号：EP22849383.9
申请日：2022-07-22
IPC分类号： C07K2/00
CPC分类号： C07K2/00
摘要： A method of identifying an unknown spliced peptide derived from a known parent peptide contained in a biological sample, the method comprising: (1) a first step involving performing mass spectrometry on the sample to obtain mass spectrometry data regarding a peptide contained in the sample; (2) a second step involving searching a primary library, which is a database of known amino acid sequences, for an amino acid sequence that matches the mass spectrometry data, to identify a parent peptide contained in the sample; (3) a third step involving creating a secondary library including a candidate group of spliced peptides obtainable from the identified parent peptide; and (4) a fourth step involving searching the secondary library for an amino acid sequence that matches the mass spectrometry data, to identify a spliced peptide contained in the sample.
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公开(公告)号：EP4375661A1
公开(公告)日：2024-05-29
申请号：EP22845900.4
申请日：2022-07-19
IPC分类号： G01N33/15 , G01N33/50 , G01N33/53 , A01K67/027 , C07K14/705
CPC分类号： C07K14/705 , G01N33/50 , G01N33/53 , A01K67/027 , G01N33/15
摘要： A level of mouse Aβ1-40 and a level of mouse APP669-711 in a biological sample derived from an AD model mouse are measured by detection of markers including mouse Aβ1-40 and mouse APP669-711; an APP669-711/Aβ1-40 ratio which is a ratio of the level of mouse APP669-711 to the level of mouse Aβ1-40 is calculated; and when the ratio in the AD model mouse is higher than the same ratio in a reference mouse in which cerebral Aβ deposition is absent, it is judged that an amount of cerebral Aβ deposition in the AD model mouse is higher than an amount of cerebral Aβ deposition in the reference mouse.
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公开(公告)号：EP3734269B1
公开(公告)日：2024-03-27
申请号：EP17936571.3
申请日：2017-12-27
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17.发明授权
公开(公告)号：EP3517928B1
公开(公告)日：2023-11-29
申请号：EP18212070.9
申请日：2018-12-12
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公开(公告)号：EP3690865B1
公开(公告)日：2023-09-27
申请号：EP20150980.9
申请日：2020-01-09
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