Self-referenced integrated biosensor based on surface plasmon resonance mediated luminescence
    17.
    发明公开
    Self-referenced integrated biosensor based on surface plasmon resonance mediated luminescence 有权
    生物传感器生物传感器基础知识

    公开(公告)号:EP1956364A1

    公开(公告)日:2008-08-13

    申请号:EP08100551.4

    申请日:2008-01-16

    IPC分类号: G01N21/55

    CPC分类号: G01N21/553

    摘要: A sensing device for characterizing a substance by modifying modes of resonance of surface plasmons is described. The sensing device (2) comprises: a photo-emitting substrate layer (4) for generating a luminescence signal; a dielectric adaptive layer (6) applied onto the photo-emitting substrate layer; and a sensing layer (8) applied onto the dielectric adaptive layer, the sensing layer having a sensing surface for coupling with the substance to be characterized. The luminescence signal generates surface plasmons having modes of resonance at the interface of the sensing layer and the substance to be characterized. The substance to be characterized, when coupled to the sensing layer, characteristically modifies the modes of resonance of the surface plasmons.

    摘要翻译: 描述了通过修改表面等离激元的谐振模式来表征物质的感测装置。 感测装置(2)包括:用于产生发光信号的光发射基底层(4); 施加到光发射基底层上的介电适应层(6); 以及施加到所述介电自适应层上的感测层(8),所述感测层具有用于与要表征的物质耦合的感测表面。 发光信号产生在感测层和要表征的物质的界面处具有谐振模式的表面等离子体激元。 待特征化的物质当耦合到感测层时,特征性地修改表面等离子体激元的共振模式。