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11.发明公开
公开(公告)号：EP2156441A1
公开(公告)日：2010-02-24
申请号：EP08737034.2
申请日：2008-04-17
发明人： AEPPLI, Gabriel , DUECK, Benjamin
IPC分类号： G12B21/20
CPC分类号： G01B11/161 , G01B11/165
摘要： Apparatus and method for measuring the deformation of a tethered or untethered cantilever by projecting a radiation beam onto the cantilever, detecting an interference pattern reflected from or transmitted through the cantilever, and calculating the deformation of the cantilever by measuring the intensity variation within at least a portion of the interference pattern.
摘要翻译： 装置和用于通过投影辐射束引导到悬臂测量系留或无缆悬臂的变形方法中，干涉图案的检测从反射式或反式通过悬臂mitted，并且通过测量内的至少一个的强度变化计算所述悬臂的变形 在干涉图案的部分。
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公开(公告)号：EP1297389B8
公开(公告)日：2010-02-03
申请号：EP01943641.9
申请日：2001-06-26
发明人： DUNNILL, Peter, University College London , HOARE, Mike, University College London , TITCHENER-HOOKER, Nigel, University College London
IPC分类号： G05B1/00
CPC分类号： G05B15/02 , G05B17/02 , G05B2219/32343 , G05B2219/32352 , Y02P90/26
摘要： A development tool (2) includes a plurality of measuring tools (71 to 76) and an industrial process simulation device (60). The simulation device (60) simulates a whole industrial scale bioprocess in order to obtain acceptable operating parameters for the industrial scale bioprocess. The measuring tools (71 to 76) enable various significant properties of the biomaterial to be measured and evaluated using only a small test quantity of the biomaterial.
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公开(公告)号：EP1559432B1
公开(公告)日：2009-08-12
申请号：EP03770047.3
申请日：2003-10-30
发明人： KWEE, Yong, c/o University College London , KOSAKA, Masaaki , KOISHIHARA, Yasuo, c/o Chugai Seiyaku K. K.
CPC分类号： A61K39/0011 , A61K2039/5154
摘要： A cancer vaccine containing as an active ingredient an antigen-specific dendritic cell pulsed by an HM1.24 protein, HM1.24 peptide or transduced with an HM1.24-encoding gene, or HM1.24 protein-encoding DNA or RNA.
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14.发明授权A polishing machine with driving means to move the grinding tool along a precession path and method to use it 有权抛光具有驱动装置装置，用于引导沿着研磨Präzessionsbahn和使用它们的方法的工具
公开(公告)号：EP1384553B1
公开(公告)日：2009-03-11
申请号：EP03078101.7
申请日：1999-12-01
IPC分类号： B24B13/015 , B24B41/04 , B24B47/12
CPC分类号： B24B13/00 , B24B1/00 , B24B7/228 , B24B7/24 , B24B7/241 , B24B13/01 , B24B13/015 , B24B13/02 , B24B17/10 , B24B29/00 , B24B41/002 , B24B41/04 , B24B47/12 , B24B51/00 , B24D3/06 , B24D3/28 , B24D3/342 , B24D9/04 , B24D11/001 , B24D13/14 , B24D13/147 , B24D13/20 , B24D18/0009 , Y10S451/90
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公开(公告)号：EP1825275A2
公开(公告)日：2007-08-29
申请号：EP05823285.1
申请日：2005-12-07
发明人： WARD, Malcolm Andrew , COLLINGE, John , JACKSON, Graham Stuart , MCGREGOR, Emma , LEEDS, Nicola Louise , CAMPBELL, James , WESTBROOK, Jules , BYERS, Helen
IPC分类号： G01N33/68
CPC分类号： G01N33/6896 , G01N2800/52
摘要： The invention relates to a method of diagnosis of vCJD in a diagnostic sample of a valid body tissue taken from a human subject, which comprises detecting an increased concentration of a protein in the diagnostic sample, compared with a sample of a control human subject, the protein being: beta-actin (SwissProt Ace. No. P60709), apolipoprotein A-IV precursor (SwissProt Acc. No. P06727); haptoglobin beta-chain consisting of residues 162-406 (SwissProt Acc. No. P00738); haemoglobin beta chain (SwissProt Ace. No. P02023); or alpha-1-antitrypsin (SwissProt Ace. No. P01009); or a decreased concentration of a protein in the diagnostic sample, compared with a sample of a control, normal human subject, the protein being plasma protease (C1) inhibitor precursor (SwissProt Acc. No. P05155); complement component 1, s sub-component (SwissProt Acc. No. P09871); butyrylcholinesterase precursor (SwissProt Acc. No. P06276); complement component C4B (SwissProt Acc. No. P01028); lumican (SwissProt Ace. No. P51884); alpha-fibrinogen precursor (SwissProt Ace. No. P02671); IGHG4 protein (Swiss Prot Ace. No. Q8TC63) or immunoglobulin lambda heavy chain. Other marker proteins are also disclosed.
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公开(公告)号：EP1825274A2
公开(公告)日：2007-08-29
申请号：EP05820667.3
申请日：2005-12-07
发明人： LEEDS, Nicola, Louise , WARD, Malcolm, Andrew , McGREGOR, Emma , TABRIZI, Sarah, Joanna , DALRYMPLE, Annette , CAMPBELL, James , WESTBROOK, Jules, Arthur , BYERS, Helen, Louise
IPC分类号： G01N33/68
CPC分类号： G01N33/6896 , G01N2800/52
摘要： The invention relates to a method of diagnosis of Huntington's Disease in a diagnostic sample of a valid body tissue taken from a human subject, which comprises detecting an altered concentration of a protein in the diagnostic sample, compared with a sample of a control human subject, the protein being selected from: Swiss Prot accession number : Protein name; P10909 : Clusterin precursor; P00738 : Haptoglobin precursor; P01009 : Alpha- l-antitrypsin precursor; P01024 : Complement C3 precursor; P01620 : 1g kappa chain V-III region; P01834 : 1g kappa chain C region P01842 : 1g lambda chain C regions; P01857 : 1g gamma-1 chain C region; P01859 : Ig gamma-2 chain C region; P01876 : 1g alpha-1 chain C region P02647 : Apolipoprotein A-I precursor; P02649 : Apolipoprotein E precursor; P02652 : Apolipoprotcin A-II precursor; P02655 : Apolipoprotein C-II precursor; P02656 : Apolipoprotein C-III precursor P02671 : Fibrinogen alpha/alpha-E chain precursor; P02763 : Alpha- l-acid glycoprotein 1 precursor; P02766 : Transthyretin precursor; P02768 : Serum albumin precursor; P02787 : Serotransferrin precursor; P04196 : Histidine-rich glycoprotein precursor; P06727 : Apolipoprotein A-IV precursor; P19652 : Alpha- l-acid glycoprotein 2 precursor; P68871/P02042 : Hemoglobin beta chain/Hemoglobin delta chain; P60709 : Beta actin.
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公开(公告)号：EP1311993B1
公开(公告)日：2007-05-30
申请号：EP01960912.2
申请日：2001-08-22
IPC分类号： G06F17/50
CPC分类号： G06T17/00
摘要： A system and method of modelling interaction between a plurality of agents and an environment, comprising providing agents with simple characteristics and storing those characteristis, storing detailed information on the complete environment and allowing the agents to access environment information from the stored detailed information on a location by location basis and use the information to progress through the environment, such that a processor can monitor these movements to determine suitability of the environment by providing an underlying environment map which is highly detailed and which is accessible by the simple agents. A more efficient and user friendly system and method for evaluating environment layouts is provided.
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公开(公告)号：EP1292248B1
公开(公告)日：2006-10-04
申请号：EP01940821.0
申请日：2001-06-22
发明人： BLUNN, Gordon , COBB, Justin , GOODSHIP, Allen , UNWIN, Paul
CPC分类号： A61F2/60 , A61C8/0006 , A61C8/0012 , A61C8/0018 , A61F2/0077 , A61F2/2814 , A61F2/30749 , A61F2/30767 , A61F2/54 , A61F2/78 , A61F2002/0081 , A61F2002/0086 , A61F2002/009 , A61F2002/30224 , A61F2002/30225 , A61F2002/30322 , A61F2002/30558 , A61F2002/3056 , A61F2002/30561 , A61F2002/30574 , A61F2002/30604 , A61F2002/30785 , A61F2002/30838 , A61F2002/30848 , A61F2002/30878 , A61F2002/30879 , A61F2002/30929 , A61F2002/3093 , A61F2002/30981 , A61F2002/7887 , A61F2230/0069 , A61F2250/0026 , A61F2250/0073 , A61F2250/0074 , A61F2310/0058 , A61F2310/00604 , A61F2310/00796 , A61F2310/00976 , A61L27/28 , A61L27/303 , A61L27/34 , A61L2430/02 , C08L89/00
摘要： A transcutaneous prosthesis includes a first component configured for attachment to a bone, the first component including flutes or grooves on a surface thereof for deterring rotation of the prosthesis within a bone; a second component adapted for location between the bone and the skin, the second component having a surface treatment for stimulation of fibroblastic cell proliferation and attachment of epithelial cells; and a third component adapted for location to extend from the skin surface and is adapted to extend directly from the skin surface in use, the third component having a coating of a non-stick material on an outer surface thereof, the coating having a surface energy that is lower than a surface energy of the first and second components and which is low enough to deter bacterial adhesion.
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公开(公告)号：EP1576746A1
公开(公告)日：2005-09-21
申请号：EP03767990.9
申请日：2003-12-12
发明人： SEEDS, Alwyn, John , WAKE, David'Croeso' , PENTY, Richard, Vincent , WEBSTER, Matthew , HARTMANN, Peter , WHITE, Ian, Hugh
CPC分类号： H04B10/2575 , H04B10/25752 , H04B10/2581
摘要： A method of transmission of radio signals over all types of graded-index multimode fibre is provided. The method comprises launching optical radiation into the core of the multimode fibre away from the centre of the core so as to strongly excite a subset of the available modes of the multimode fibre. The subset of modes excited are within a small number of mode groups and thus have similar propagation constants leading to a reduction in modal dispersion and modal interference and smoothing of the frequency response passband region beyond the fibres specified 3dB base band bandwidth assisting RF transmission and recovery from this region.
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公开(公告)号：EP1206675B1
公开(公告)日：2005-06-29
申请号：EP00954748.0
申请日：2000-08-18
发明人： BEARD, Paul , MILLS, Timothy Noel , DELPY, David
IPC分类号： G01B9/02
CPC分类号： G01B9/02023 , G01B2290/25
摘要： A method of forming an interferometer film for an interferometer sensor comprises forming a parylene polymer layer (8) of substantially uniform thickness directly on an interferometer substrate (4;45), the layer forming the interferometer film. Since the interferometer film (8) is formed directly onto the surface of the interferometer substrate, there is improved conformity between the two surfaces at the interface between the polymer layer and the substrate and improved uniformity in the thickness of the film.
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