摘要:
A device for transdermal and/or intradermal transport that can be connected to two electrodes, wherein one of the electrodes is configured for containing an active principle to be administered via transdermal and/or intradermal route. The device comprises a wave generator configured for generating a driving signal to be sent to the electrodes. In one embodiment, the driving signal comprises a plurality of packets grouped in trains of packets (Tr) and in groups of trains (TG), wherein each packet consists of a unidirectional signal that results from the combination of a modulating signal and a carrier signal, wherein each train of packets (Tr) consists of a series of packets, and wherein each group of trains (TG) comprises a series of trains of packets (Tr). In addition, the wave generator can be configured for reversing the polarity of the trains of packets (Tr) after a given time interval.
摘要:
An embodiment in accordance with the present invention provides a device and method to deliver direct ionic current safely to target neural tissue, while also eliminating interruptions in the output of the device that can result from the non-ideal operation of the valves used to control the current flow in the device. The device includes two valve-operated systems that work in tandem. The first and second current producing systems are configured to be used together in order to eliminate the periodic interruptions in current flow. In use, one system drives current through the target tissue, while the other system closes all of the valves first and then opens its valves in sequence. This intermediate step of closing all of the valves prevents unintended current shunts through either system. The device also includes two conductors to direct the flow of direct current into the target tissue.
摘要:
The present invention relates to a facial massager, which can significantly enhance an iontophoresis function by applying a large quantity of electric current on the skin of the human body, by means of forming a relatively high potential difference between power terminals having different polarities without requiring a separate voltage booster circuit, and can also apply stimulation to the entire face or locally by individually actuating electric modules of a mask even without external power. The facial massager, according to the present invention, comprises: the mask which is provided with an accommodation space therein, and external exposure holes of terminals for applying the electric current on the skin of the human body; and at least one electric module, which is accommodated in the accommodation portion of the mask that is provided with a rotary shaft and a coil that wraps the rotary shaft from the outside, comprising a driving portion, for exposing two terminals having different polarities through the external exposure holes, thereby increasing the potential difference between the two terminals by using inductance of the coil.
摘要:
A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between, the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.
摘要:
Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.
摘要:
L'invention concerne un dispositif de iontophorèse oculaire (1) permettant d'administrer un médicament dans un oeil et comprenant : un réservoir (20), le réservoir ayant une extrémité proximale et une extrémité distale, l'extrémité proximale comprenant une lèvre souple (21) pouvant entrer en prise avec l'oeil afin d'administrer le médicament ; une électrode active (10) disposée tout près de l'extrémité distale du réservoir, l'électrode active étant incurvée et présentant un rayon de courbure interne proche du rayon de courbure de la cornée de l'oeil ; et un médicament stocké dans le réservoir.
摘要:
An electrode assembly for use with a drug delivery device comprises means for carrying a medicament (76), an active electrode (78) in electrical communication with the carrying means (76), at least one passive electrodes (80) and a separator pad (28) surrounding the carrying means (76). A moat region (94) is disposed between the separator pad (28) and the carrying means (76) that prevents migration of the medicament between the carrying means (76) and the at least one passive electrode (80). Means (74) for securing the electrode assembly to a surface of a patient are provided.