公开(公告)号：EP2997984B1

公开(公告)日：2020-06-03

申请号：EP15185576.4

申请日：2015-09-17

申请人： Institute Jozef Stefan ,  University of Maribor

发明人： KOLAR, Metod ,  MOZETIC, Miran ,  JUNKAR, Ita ,  VESEL, Alenka ,  MODIC, Martina ,  KLEINSCHEK, Karin Stana

IPC分类号： A61L27/18 ,  A61L27/34 ,  A61L27/54 ,  A61L29/06 ,  A61L29/08 ,  A61L29/16 ,  A61L31/06 ,  A61L31/10 ,  A61L31/16 ,  A61L33/00

公开(公告)号：EP2793912B1

公开(公告)日：2020-03-18

申请号：EP12860504.5

申请日：2012-12-21

申请人： Celularity, Inc.

发明人： BHATIA, Mohit, B. ,  HARIRI, Robert, J. ,  HOFGARTNER, Wolfgang ,  WANG, Jia-lun ,  YI, Qian

IPC分类号： A61K9/14 ,  A61F13/00 ,  A61L33/00 ,  A61L27/48 ,  A61K35/50 ,  A61L27/36 ,  A61P3/00 ,  A61P5/00 ,  A61P15/08

公开(公告)号：EP3615100A1

公开(公告)日：2020-03-04

申请号：EP18717389.3

申请日：2018-04-19

申请人： Solvay Specialty Polymers Italy S.p.A.

发明人： AHUJA, Ritu ,  NALAWADE, Trupti ,  DINICOLO', Emanuele ,  FONTANA, Giovanni ,  WLASSICS, Ivan, Diego ,  MARCHIONNI, Giuseppe ,  TONELLI, Claudio, Adolfo, Pietro

IPC分类号： A61L33/00 ,  A61M1/16 ,  B01D71/80 ,  C08K3/00 ,  C08G65/32 ,  C08G65/334 ,  C08G65/38 ,  C08G65/40 ,  C08G75/23

公开(公告)号：EP2809152B1

公开(公告)日：2019-11-20

申请号：EP13709561.8

申请日：2013-01-31

申请人： Nayacure Therapeutics Ltd.

发明人： COHEN, Shahar

IPC分类号： A01N1/02 ,  A61B5/00 ,  A61B17/00 ,  A61L33/00 ,  A61L27/36

公开(公告)号：EP2313122B1

公开(公告)日：2019-03-06

申请号：EP09798764.8

申请日：2009-07-16

申请人： Micell Technologies, Inc.

发明人： MCCLAIN, James, B. ,  TAYLOR, Douglas ,  NEET, John

IPC分类号： A61L33/00 ,  A61L27/34 ,  A61L27/50 ,  A61L27/54 ,  A61L29/14 ,  A61L29/16 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L29/08 ,  A61L17/00 ,  A61L17/14

公开(公告)号：EP3436101A1

公开(公告)日：2019-02-06

申请号：EP17715357.4

申请日：2017-03-23

申请人： Cook Medical Technologies LLC

发明人： GUNNING, Padraig, M.

IPC分类号： A61L31/10 ,  A61L31/14 ,  A61L33/00 ,  A61L33/06

公开(公告)号：EP2959925B1

公开(公告)日：2018-08-29

申请号：EP15176192.1

申请日：2007-09-13

申请人： Boston Scientific Limited

发明人： GIRTON, Timothy S.

IPC分类号： A61L31/14 ,  A61L31/16 ,  A61L27/56 ,  A61L33/00 ,  A61F2/07 ,  A61F2/82 ,  A61L2/235

CPC分类号： A61L31/146 ,  A61F2/07 ,  A61F2/82 ,  A61F2250/0023 ,  A61L2/235 ,  A61L27/56 ,  A61L31/148 ,  A61L31/16 ,  A61L33/007 ,  A61L2300/00 ,  A61L2400/08

摘要： Medical devices, such as endoprostheses, and related methods are disclosed

公开(公告)号：EP3088014B1

公开(公告)日：2018-06-20

申请号：EP14875327.0

申请日：2014-12-19

申请人： Terumo Kabushiki Kaisha

发明人： ANZAI, Takao ,  NISHIDA, Kaori

IPC分类号： A61L33/00 ,  A61L29/00 ,  A61L31/00 ,  A61L33/06

CPC分类号： A61L33/0035 ,  A61L31/048 ,  A61L31/16 ,  A61L33/0023 ,  A61L33/064 ,  A61L33/068 ,  A61L2300/42 ,  A61L2300/604 ,  A61L2300/606 ,  A61L2420/02 ,  C08L33/12

摘要： The invention relates to a medical device including a base member and a coating layer containing an antithrombogenic material and covering a surface of the base member. The antithrombogenic material contains a copolymer having a repeating unit (A) represented by the following formula (1) : wherein R 11 is a hydrogen atom or a methyl group, Z is an oxygen atom or -NH-, R 12 is a C 1-6 alkylene group, R 13 and R 14 are each independently a C 1-4 alkyl group, and R 15 is a C 1-2 alkylene group, and a repeating unit (B) represented by the following formula (2): wherein R 21 is a hydrogen atom or a methyl group, R 22 is a C 1-6 alkylene group, and R 23 is a C 1-4 alkyl group. The repeating unit (A) is contained in a proportion of 1 to 7 mol% based on all the structural units of the copolymer. The invention makes it possible to provide a medical device having excellent antithrombogenicity even under severe use conditions prone to thrombus formation.

公开(公告)号：EP2736456B1

公开(公告)日：2018-06-13

申请号：EP12819965.0

申请日：2012-07-30

申请人： Carnegie Mellon University ,  University of Pittsburgh - Of the Commonwealth System of Higher Education

发明人： YOSHIDA, Masahiro ,  BERNSTEIN, C. Douglas ,  DUR, Onur ,  PEKKAN, Kerem

IPC分类号： A61F2/24 ,  A61F2/06 ,  A61L27/16 ,  A61L33/00

CPC分类号： A61F2/2412 ,  A61F2/06 ,  A61F2/2403 ,  A61F2/2409 ,  A61F2/2415 ,  A61F2/2475 ,  A61F2002/068 ,  A61F2250/0037 ,  A61F2250/0067 ,  A61F2250/0082 ,  A61L27/16 ,  A61L27/24 ,  A61L27/367 ,  A61L27/58 ,  A61L33/0011 ,  A61L2430/20 ,  Y10T29/49412 ,  C08L27/18

摘要： Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.

公开(公告)号：EP3328457A1

公开(公告)日：2018-06-06

申请号：EP16831157.9

申请日：2016-07-22

申请人： The Texas A&M University System

发明人： MUSCHALEK, Rachael ,  HEARON, Keith ,  NASH, Landon D. ,  MAITLAND, Duncan J.

IPC分类号： A61L33/00

CPC分类号： A61L31/10 ,  A61L17/145 ,  A61L27/34 ,  A61L27/56 ,  A61L31/146 ,  A61L2400/16 ,  C08L75/04

摘要： An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein.