-
公开(公告)号：EP2987858B1
公开(公告)日：2019-08-14
申请号：EP14786082.9
申请日：2014-04-17
-
公开(公告)号：EP2832338B1
公开(公告)日：2019-07-17
申请号：EP13770071.2
申请日：2013-03-29
-
公开(公告)号：EP2873645B1
公开(公告)日：2019-05-08
申请号：EP13817567.4
申请日：2013-06-17
IPC分类号： C01B15/029 , B01J23/52
-
公开(公告)号：EP3466978A1
公开(公告)日：2019-04-10
申请号：EP17806675.9
申请日：2017-05-30
发明人： NAKAMURA, Takahiro , YAGI, Yusuke
IPC分类号： C07K19/00 , C07K14/415 , C07K14/435 , C12N15/09
摘要： [Problem to be Solved] The object of the present invention is to develop a method of regulating a target RNA.
[Solution] There is provided a fusion protein comprising a functional domain which improves the protein expression level from mRNA and a PPR protein which can bind to a target mRNA in an RNA base-selective or RNA base sequence-specific manner.-
公开(公告)号：EP3434198A1
公开(公告)日：2019-01-30
申请号：EP17769882.6
申请日：2017-03-06
发明人： YOSHIMI Yukiharu , KAWAI Hirohisa , IKEDA Tetsuo
IPC分类号： A61B17/062 , A61B17/29
摘要： A cooling device 10 may be configured to cool a shape-memory alloy member. The cooling device 10 may include: a cooling unit 20 configured to cool the shape-memory alloy member or a part that is to make contact with the shape-memory alloy member; a refrigerant supply pipe 30, 31 including one end connected to a refrigerant supply source 34 and other end connected to the cooling unit 20, the refrigerant supply pipe 30, 31 configured to supply a refrigerant supplied from the refrigerant supply source 34 to the cooling unit 20; and a refrigerant discharge pipe 32, 33 including one end connected to the cooling unit 20, the refrigerant discharge pipe 32, 33 configured to discharge the refrigerant discharged from the cooling unit 20 from other end of the refrigerant discharge pipe 32, 33.
-
-
27.发明公开
公开(公告)号：EP3409291A1
公开(公告)日：2018-12-05
申请号：EP17744444.5
申请日：2017-01-27
发明人： ONO, Fumiyasu , GOTO, Masahiro , HIRATA, Osamu , IWAMA, Takehisa
摘要： The present invention addresses the problem of providing a method for increasing the transdermal absorption of a water-soluble drug in a simple manner without relying on the formation of a prodrug of the water-soluble drug by organic synthesis. The present invention relates to: a complex which is formed from a water-soluble active ingredient and a fat-soluble compound having an aldehyde group through an interaction capable of being dissociated in water; a transdermally absorbable composition comprising the complex, a transdermal absorption controlling agent and a fat-soluble medium; and a method for controlling the release of the water-soluble active ingredient from the complex in skin.
-
公开(公告)号：EP3404734A1
公开(公告)日：2018-11-21
申请号：EP16885094.9
申请日：2016-12-16
发明人： NAKANOTANI Hajime , FURUKAWA Taro , ADACHI Chihaya
摘要： An organic electroluminescent device having a donor layer containing a donor compound, a spacer layer containing a spacer compound, and an acceptor layer containing an acceptor compound in that order, wherein the donor compound and the acceptor compound are compounds to form an exciplex to radiate delayed fluorescence, and the excited triplet energy of the spacer compound is higher than the excited triplet energy of the exciplex, can be controlled to have different emission wavelengths not requiring change of the combination of the donor compound and the acceptor compound therein.
-
公开(公告)号：EP3363499A1
公开(公告)日：2018-08-22
申请号：EP18163771.1
申请日：2011-06-10
发明人： TAKAYANAGI, Shin-ichiro , TOMURA, Hitomi , TAWARA, Tomonori , INAGAKI, Yoshimasa , AKASHI, Koichi , KUBOTA, Tsuguo , KIKUSHIGE, Yoshikane
IPC分类号： A61P7/00 , A61K39/00 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/08
CPC分类号： C07K16/2803 , C07K16/2818 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/92 , G01N33/56972
摘要： The present invention provides an anti-human TIM-3 antibody which binds to the amino acid sequence of the extracellular region of TIM-3 or its three-dimensional structure thereof and exhibits higher effector activity such as an antibody-dependent cellular cytotoxicity (ADCC activity) for diseases relating to a human TIM-3 expressing cell. The present invention provides a monoclonal antibody or antibody fragment thereof which binds to the amino acid sequence of the extracellular region of TIM-3 or its three-dimensional structure and exhibits ADCC activity; a hybridoma which produces the antibody; a DNA encoding the antibody; a vector comprising the DNA; a transformant which is obtainable by introducing the vector; a method for producing the antibody or the antibody fragment thereof which comprises using the hybridoma or the transformant; a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment thereof as an active ingredient. In addition, the present invention provides an anti-human TIM-3 antibody having high ADCC activity by screening an anti-human TIM-3 antibody which competes with the monoclonal antibody or the antibody fragment thereof.
-
公开(公告)号：EP2242326B1
公开(公告)日：2018-05-30
申请号：EP09705079.3
申请日：2009-01-28
发明人： FURUKAWA, Hiroshi
CPC分类号： H04W28/14
摘要： There is proposed a network system and the like achieving a packet relay transmission with high relay transmission efficiency according to Intermittent Periodic Transmit method (IPT). In order to achieve Intermittent Periodic Transmit in a mesh cluster, a communication control unit 35 of a core node 21 selects one of a plurality of communication units 29 1 , ..., 29 N according to downlink priority and causes the selected communication unit to transmit a packet with a periodic interval. In order to transmit a packet from the core node to another slave node, a communication control unit 55 of a slave node 41 selects one of the communication units according to downlink priority, and in order to transmit a packet from a slave node to the core node, the communication control unit 55 of the slave node 41 selects one of the communication units according to uplink priority. Then, the communication control unit 55 causes the selected communication unit to transmit the packet.
-
-
-
-
-
-
-
-
-
搜索结果
437 条记录 (耗时 0.039 秒)
