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公开(公告)号：EP3094338A1
公开(公告)日：2016-11-23
申请号：EP15701244.4
申请日：2015-01-16
CPC分类号： C12N7/00 , C12N7/045 , C12N2760/16132 , C12N2760/16162 , C12Q1/701
摘要： The invention relates to defective interfering viruses and defective interfering virus RNAs that are effective as antiviral agents. The invention also relates to methods for identifying defective interfering virus RNAs that can be used as effective antiviral agents.
摘要翻译： 本发明涉及作为抗病毒剂有效的缺陷性干扰病毒和有缺陷的干扰性病毒RNA。 本发明还涉及用于鉴定可用作有效的抗病毒剂的有缺陷的干扰性病毒RNA的方法。
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公开(公告)号：EP3005224A2
公开(公告)日：2016-04-13
申请号：EP14726185.3
申请日：2014-03-28
发明人： LI, Chang-Tsun , YAO, Yi
CPC分类号： G06K9/00335 , G06K9/00355 , G06K9/40 , G06K9/4652 , G06K9/4671 , G06K9/6202 , G06K9/6277 , G06T7/11 , G06T7/246 , G06T7/248 , G06T7/73 , G06T7/90 , G06T2207/10024 , G06T2207/30196 , G06T2207/30201
摘要： A method of tracking the position of a body part, such as a hand, in captured images, the method comprising capturing (10) colour images of a region to form a set of captured images; identifying contiguous skin-colour regions (12) within an initial image of the set of captured images; defining regions of interest (16) containing the skin-coloured regions; extracting (18) image features in the regions of interest, each image feature relating to a point in a region of interest; and then, for successive pairs of images comprising a first image and a second image, the first pair of images having as the first image the initial image and a later image, following pairs of images each including as the first image the second image from the preceding pair and a later image as the second image: extracting (22) image features, each image feature relating to a point in the second image; determining matches (24) between image features relating to the second image and image features relating to in each region of interest in the first image; determining the displacement within the image of the matched image features between the first and second images; disregarding (28) matched features whose displacement is not within a range of displacements; determining regions of interest (30) in the second image containing the matched features which have not been disregarded; and determining the direction of movement (34) of the regions of interest between the first image and the second image.
摘要翻译： 一种在拍摄图像中跟踪身体部位（例如手）的位置的方法，所述方法包括捕获（10）区域的彩色图像以形成一组捕获图像; 识别所述一组捕获图像的初始图像内的连续肤色区域（12）; 限定含有肤色区域的感兴趣区域（16） 提取（18）感兴趣区域中的图像特征，每个图像特征与感兴趣区域中的点相关; 然后，对于包括第一图像和第二图像的连续图像对，第一对图像具有作为第一图像的初始图像和稍后图像，后续图像对，每个图像包括来自第一图像的第二图像作为第一图像 前一对和后一图像作为第二图像：提取（22）图像特征，与第二图像中的点相关的每个图像特征; 确定与所述第二图像相关的图像特征和与所述第一图像中的每个感兴趣区域相关的图像特征之间的匹配（24）; 确定第一和第二图像之间的匹配图像特征的图像内的位移; 忽略（28）位移不在位移范围内的匹配特征; 确定包含未被忽略的匹配特征的第二图像中的感兴趣区域（30）; 以及确定第一图像和第二图像之间的感兴趣区域的移动方向（34）。
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公开(公告)号：EP2589093B1
公开(公告)日：2014-08-20
申请号：EP11743128.8
申请日：2011-06-30
CPC分类号： H01L51/442 , H01L51/0021 , H01L51/422 , H01L51/424 , H01L51/4253 , Y02E10/549 , Y02P70/521
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24.发明公开METHOD FOR IDENTIFYING MODULATORS OF HCV TRANSLATION OR REPLICATION INVOLVING THE NS5B POLYPEPTIDE AND A PSEUDOKNOT 审中-公开一种用于识别翻译HCV或复制的调节剂BY NS5B多肽假结节
公开(公告)号：EP2744921A1
公开(公告)日：2014-06-25
申请号：EP12753801.5
申请日：2012-08-17
发明人： EVANS, David J. , SIMMONDS, Peter
IPC分类号： C12Q1/70
CPC分类号： C12Q1/707 , C12N15/1131 , C12Q2600/136
摘要： The invention relates to a method for identifying compounds that act as modulators of hepatitis C (HCV) translation and/or replication, and to compounds identified by this method, and their uses in medicine. The invention also relates to an RNA useful for identifying modulators of HCV translation and/or replication. The invention further relates to a method for producing a replication-competent HCV virus.
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公开(公告)号：EP2603801A1
公开(公告)日：2013-06-19
申请号：EP11757401.2
申请日：2011-08-11
发明人： UNWIN, Patrick , EBEJER, Neil
IPC分类号： G01Q60/60 , B82Y35/00 , G01N27/416
CPC分类号： G01N27/416 , B82Y35/00 , G01Q60/60
摘要： Apparatus comprises a pipet comprising first and second channels separated by a septum and having a tip at which each of the first and second channels is open; an electrolyte solution contained within both the first and second channels of the pipet; a first electrode extending into the electrolyte in the first channel of the pipet; a second electrode extending into the electrolyte in the second channel of the pipet; means for applying a potential difference between the first and second electrodes; means for measuring alternating current components of a current flowing to or from the first electrode; means for applying an oscillatory perturbation to the pipet; and means responsive to the alternating current measured to be flowing to or from the first electrode to adjust a position of the pipet such as to control a separation between the tip of the pipet and a surface of interest.
摘要翻译： 装置包括移液管，其包括由隔膜隔开的第一通道和第二通道，并具有第一通道和第二通道中的每个通道打开的顶端; 包含在移液管的第一和第二通道内的电解质溶液; 在移液管的第一通道中延伸到电解质中的第一电极; 在移液管的第二通道中延伸到电解质中的第二电极; 用于在第一和第二电极之间施加电位差的装置; 用于测量流向或来自第一电极的电流的交流分量的装置; 用于对移液器施加振荡扰动的装置; 以及响应于测量的交流电流流向或来自第一电极以调节移液管的位置的装置，以便控制移液管的尖端和感兴趣的表面之间的间隔。
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26.发明公开PREVENTION OF PROTEOMIC AND GENOMIC DAMAGE BY DICARBONYL SUBSTRATES OF GLO 1 审中-公开避免DICARBONYLSUBSTRATE GLO1混合PROTEO和基因组的损害
公开(公告)号：EP2585058A2
公开(公告)日：2013-05-01
申请号：EP11731484.9
申请日：2011-06-20
发明人： THORNALLEY, Paul , RABBANI, Naila , XUE, Mingzhan
CPC分类号： A61K31/26 , A61K45/06 , C07C331/20 , C07C331/22 , C12N9/88 , C12Q1/25 , G01N2500/00 , G01N2570/00 , A61K2300/00
摘要： The invention concerns the role of Glo 1 in the prevention and reversal of proteomic and genomic damage by dicarbonyl substrates thereof and, in particular, therapeutics that promote Glo 1 production.
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27.发明授权
公开(公告)号：EP2355834B1
公开(公告)日：2013-05-01
申请号：EP09774920.4
申请日：2009-12-08
发明人： DIMMOCK, Nigel , EASTON, Andrew
CPC分类号： C12N7/00 , A61K35/76 , C12N2760/16132 , C12N2760/16162
摘要： The invention relates to virology and the prevention and/or treatment of viral infection and disease in animals, including birds and humans. The invention relates to the field of antiviral treatments. The invention further relates to methods of stimulating innate immunity and natural interferon production in humans or animals and in component parts of humans or animals, including cells and tissues. The invention also relates to the field of defective interfering (DI) viruses, including cloned DI viruses.
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公开(公告)号：EP2015792A1
公开(公告)日：2009-01-21
申请号：EP07732557.9
申请日：2007-04-25
CPC分类号： A61F13/00 , A61L27/3834 , A61L27/3839 , A61L27/56 , A61L27/58 , B28B3/20 , B29C47/0004 , B29C47/0016 , B33Y80/00
摘要： The invention provides a process for the production of a monolithic implant for use in tissue engineering, the process comprising the steps of plasticising at least one biocompatible material into a paste, extruding the paste through a die, and drying the extruded material to eliminate an aqueous and/or non-aqueous component. The invention also relates to a monolithic implant as thereby manufactured, and the use of such an implant as a scaffold for tissue-engineering and as a transplant tissue in reconstructive or replacement surgery.
摘要翻译： 本发明提供了一种用于生产用于组织工程的整体植入物的方法，该方法包括以下步骤：将至少一种生物相容性材料增塑成糊状物，通过模具挤出糊料，并干燥挤出的材料以消除水性 和/或非水组分。 本发明还涉及由此制造的整体式植入物，以及这种植入物作为组织工程用支架和重建或替代手术中的移植组织的用途。
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公开(公告)号：EP1372374B1
公开(公告)日：2007-01-31
申请号：EP02706934.3
申请日：2002-03-26
IPC分类号： A01G1/04
摘要： The use of dewatered small particle tailings material derived from the industrial washing of coal, metal ores, rocks and extracted minerals as a component of casing material for the cultivation of mushrooms ( Agaricus bisporus and other Agaricus spp.) is described.
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公开(公告)号：EP1346600A2
公开(公告)日：2003-09-24
申请号：EP01270080.3
申请日：2001-12-05
IPC分类号： H04R7/00
CPC分类号： H04R7/06
摘要： A loudspeaker system comprises a flexible paper or plastics diaphragm 1 for displacing a quantity of a transmitting medium to generate sound, waveform-sampling circuitry for supplying a series of sample drive signals of varying amplitude indicative of the amplitudes of an electrical input signal having an audio waveform at a series of sampling points distributed over a period of the waveform, and a piezoelectric actuator 4 for actuating the diaphragm 1 in response to each of the drive signals supplied by the waveform-sampling circuitry to cause corresponding displacement of the transmitting medium such that the combined effect of such displacement by all the drive signals is to produce a synthesised sound wave within the transmitting medium mimicking the waveform of the input signal
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