公开(公告)号：EP2858612A1

公开(公告)日：2015-04-15

申请号：EP12726789.6

申请日：2012-06-07

申请人： WaveLight GmbH

发明人： KLENKE, Jörg ,  SKERL, Katrin ,  SEILER, Theo

IPC分类号： A61F9/008

CPC分类号： A61F9/00836 ,  A61B90/39 ,  A61B2090/3912 ,  A61B2090/3937 ,  A61B2090/3983 ,  A61F9/00827 ,  A61F2009/00844 ,  A61F2009/00872

摘要： In certain embodiments, marking a lenticule includes controlling a focus of pulsed laser radiation having ultrashort pulses. A lenticule marking is created in a cornea of an eye with the pulsed laser radiation to mark the lenticule. The lenticule is then created in the cornea with the pulsed laser radiation.

摘要翻译： 在某些实施例中，标记微透镜包括控制具有超短脉冲的脉冲激光辐射的焦点。 用脉冲激光辐射在眼角膜中产生微透镜标记以标记微透镜。 然后用脉冲激光辐射在角膜中产生微透镜。

公开(公告)号：EP2854776A2

公开(公告)日：2015-04-08

申请号：EP13726776.1

申请日：2013-05-31

申请人： University College Dublin National University Of Ireland, Dublin

发明人： LEE, Gil ,  O'MAHONY, James ,  PLATT, Mark

IPC分类号： A61K9/50 ,  B01J13/04

摘要： There is provided a method of producing microparticles using an emulsion based synthesis route including: Providing a first fluid phase and a second fluid phase, wherein the first fluid phase is a continuous phase and the second fluid phase is a dispersed phase comprising a dispersed material, wherein the continuous phase is immiscible with the dispersed phase; Mixing the first continuous phase and the second dispersed phase in the presence of a surfactant in a shear device to form an emulsion of droplets of controllable size and having a narrow drop size distribution; Drying the emulsion to form microparticles of controllable size and having narrow size distribution, and wherein the microparticles may comprise spherical, crumpled, dimpled, porous or hollow microparticles morphology. Also provided is a system including shear device and drying arrangement. Also provided are micro particles of controllable size and morphology formed by the method.

摘要翻译： 提供了使用基于乳液的合成途径制备微粒的方法，包括：提供第一流体相和第二流体相，其中第一流体相是连续相，第二流体相是包含分散材料的分散相， 其中连续相与分散相不混溶; 在剪切装置中在存在表面活性剂的情况下将第一连续相和第二分散相混合以形成可控尺寸并具有窄液滴尺寸分布的液滴的乳液; 干燥乳液以形成尺寸可控并且具有窄尺寸分布的微粒，并且其中微粒可以包含球形，皱巴巴的，凹陷的，多孔的或中空的微粒形态。 还提供了包括剪切装置和干燥装置的系统。 还提供了通过该方法形成的可控尺寸和形态的微粒。

公开(公告)号：EP2826436A2

公开(公告)日：2015-01-21

申请号：EP14185132.9

申请日：2008-09-05

申请人： Alcon LenSx, Inc.

发明人： Kurtz, Ronald M. ,  Raksi, Ferenc ,  Karavitis, Michael

IPC分类号： A61B18/20 ,  A61B18/00 ,  A61B6/00 ,  A61B3/10 ,  A61F9/008 ,  A61B17/00 ,  A61B19/00 ,  A61F9/009 ,  A61B5/00

CPC分类号： A61F9/0084 ,  A61B5/0066 ,  A61B18/20 ,  A61B2017/00057 ,  A61B2090/378 ,  A61B2090/3937 ,  A61B2560/0233 ,  A61F9/00825 ,  A61F9/009 ,  A61F2009/00844 ,  A61F2009/00851 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088 ,  A61F2009/00882 ,  A61F2009/00897

摘要： Techniques, apparatus and systems for laser surgery including imaging-guided surgery techniques, apparatus and systems.

摘要翻译： 用于激光手术的技术，装置和系统，包括成像引导的手术技术，装置和系统。

公开(公告)号：EP2614801B1

公开(公告)日：2014-05-28

申请号：EP13162990.9

申请日：2010-09-02

申请人： ALCON RESEARCH, LTD.

发明人： Rickard, Matthew J.A.

IPC分类号： A61F9/007

CPC分类号： A61F9/00781

公开(公告)号：EP2729256A2

公开(公告)日：2014-05-14

申请号：EP12733497.7

申请日：2012-07-09

申请人： University College Dublin National University Of Ireland, Dublin

发明人： LEE, Gil ,  LI, Peng ,  PLATT, Mark ,  CANNON, Gemma

IPC分类号： B03C1/032 ,  B03C1/28 ,  B03C1/24

CPC分类号： B03C1/288 ,  B03C1/01 ,  B03C2201/18 ,  B03C2201/26 ,  G01N27/745 ,  G01N33/54326

摘要： There is provided a method of aggregating a plurality of beads in a magnetic bead aggregation assay for subsequent analysis comprising: - providing magnetic beads comprising a capture probe for binding with said target analyte; - reacting the magnetic beads with the sample including a target analyte in a reaction chamber aggregating the magnetic beads in the presence of a magnetic field with the target analyte to allow formation of magnetic bead aggregates having physical properties detectable to enable characterisation of the aggregates on an aggregate by aggregate basis using a detector to measure the physical properties of the aggregates. Further provided are a method and system for detecting analytes in a sample by characterising the magnetic bead aggregates on an aggregate by aggregate basis by measuring physical properties of the aggregates.

公开(公告)号：EP2717812A1

公开(公告)日：2014-04-16

申请号：EP12838539.0

申请日：2012-09-10

申请人： Novartis AG

发明人： DOWNER, David

IPC分类号： A61F9/007

CPC分类号： A61F2/1678 ,  A61F2/1662 ,  A61F9/0017

摘要： Various systems, apparatuses, and processes may be used for intraocular lens surgery. In particular implementations, a system for intraocular lens surgery may include an intraocular lens insertion cartridge and an intraocular lens interface adapted to engage an intraocular lens for advancement through the intraocular lens insertion cartridge. The system may also include a bracket that is detachably attached to the intraocular lens insertion cartridge and that facilitates securing the intraocular lens interface relative to the intraocular lens insertion cartridge.

公开(公告)号：EP2688531A1

公开(公告)日：2014-01-29

申请号：EP11764383.3

申请日：2011-09-13

申请人： Alcon LenSx, Inc.

发明人： CHAUDHARY, Gautam ,  GOLDSTEIN, Peter ,  HEGEDUS, Imre ,  SUÁREZ, Carlos German ,  CALLIGORI, David ,  KARAVITIS, Michael

IPC分类号： A61F9/008 ,  A61B18/20

CPC分类号： A61F9/00825 ,  A61B2018/00636 ,  A61F2009/00844 ,  A61F2009/00851 ,  A61F2009/0087 ,  A61F2009/00889

摘要： An imaging-based laser system can include a laser-beam system, configured to generate and scan a beam of laser pulses with an adjustable laser-power parameter to points of a scan-pattern in an eye, and an imaging-based laser-controller, configured to image a layer in the eye, to control the scanning of the beam of laser pulses to the points of the scan-pattern, and to control a laser-power parameter of the laser pulses according to the distance of the points of the scan-pattern from the imaged layer.

摘要翻译： 基于成像的激光系统可以包括激光束系统，其被配置为产生并扫描具有可调激光功率参数的激光脉冲束到眼睛中的扫描图案的点，以及基于成像的激光控制器 ，其被配置为对所述眼睛中的层进行成像，以控制将所述激光脉冲束扫描到所述扫描图案的所述点，并且根据所述扫描图案的所述点的距离来控制所述激光脉冲的激光功率参数 来自成像层的扫描图案。

公开(公告)号：EP2680799A1

公开(公告)日：2014-01-08

申请号：EP12722017.6

申请日：2012-05-04

申请人： Alcon LenSx, Inc.

发明人： RAKSI, Ferenc ,  LUMMIS, Wesley William

IPC分类号： A61F9/009

CPC分类号： A61F9/009 ,  A61F2009/00851 ,  A61F2009/00872 ,  A61F2009/00887 ,  A61F2009/00897

摘要： An adjusting ophthalmic docking system is described that includes a curved contact element, disposed on a procedure eye, a conformation platform at a distal tip of an optical system to support an adjustment of the curved contact element, and a connector to accommodate the adjustment of the contact element. The curved contact element can be a meniscus-shaped contact lens, with a proximal surface radius larger than a distal surface radius. The contact lens can be made of an approximately refractive index-matching material, such as a fluoro-polymer.

公开(公告)号：EP2680740A2

公开(公告)日：2014-01-08

申请号：EP12720361.0

申请日：2012-05-01

申请人： Alcon LenSx, Inc.

发明人： JUHASZ, Tibor ,  RAKSI, Ferenc ,  HOLLAND, Guy

IPC分类号： A61B3/13 ,  G02B7/00 ,  A61B3/00 ,  A61B3/12 ,  A61B3/10 ,  A61B3/15

CPC分类号： G02B7/004 ,  A61B3/102 ,  A61B3/152 ,  G02B7/005

摘要： An ophthalmic system is provided that includes an ophthalmic imaging device to generate an image of a portion of an imaged eye of a patient, an image processor to determine a misalignment of the imaged eye and the imaging device by processing the generated image, and to generate a control signal according to the determined misalignment, and a misalignment-reduction system to receive the control signal, and to generate a misalignment-reduction response. The misalignment-reduction system can include a fixation light system or a gantry. In some cases a locator light system may provide additional alignment information for the image processor.

公开(公告)号：EP2512322A1

公开(公告)日：2012-10-24

申请号：EP10838051.0

申请日：2010-10-13

申请人： Alcon Research, Ltd.

发明人： ARTSYUKHOVICH, Alexander

IPC分类号： A61B3/10

CPC分类号： A61B3/0008

摘要： Photonic lattice sources drive an optical fiber in an ophthalmic illuminator to illuminate the interior of an eye. To produce white light, an RGB combination of photonic lattice LEDs may be used. Alternatively, a bichromatic combination of photonic lattice LEDs produce white light.