公开(公告)号：EP0796129A1

公开(公告)日：1997-09-24

申请号：EP95939989.0

申请日：1995-11-13

申请人： MEDTRONIC, INC.

发明人： STROEBEL, John, C. ,  MARKOWITZ, H., Toby

IPC分类号： A61N1

CPC分类号： A61N1/368 ,  A61N1/36585

摘要： A dual chamber, rate-responsive pacemaker for pacing a patient's heart novelly allows tracking of the patient's sinus rate when the sinus rate is slightly less than the sensor rate; i.e., within a predetermined 'Sinus Preference Window Maximum Rate Drop'. Pacing at the sensor rate occurs when the sensor rate exceeds the sinus rate by more than the Sinus Preference Window Maximum Rate Drop. In the preferred embodiment a Sinus Preference Window, which occurs at the end of the ventricle-to-atrium interval, is decremented with successive heart beats by a programmable delta to increase the pacing rate until the Sinus Preference Window reaches zero, in which case the pacemaker paces at the sensor rate. The Sinus Preference Window is reset to its maximum value upon either the detection of an atrial sensed event, or upon the expiration of a programmable Sinus Check Interval. The pacemaker paces at the sinus rate or the maximum rate drop rate, whichever is faster, for a number of recovery beats, and then increments the pacing rate up to the sensor rate.

公开(公告)号：EP0794812A2

公开(公告)日：1997-09-17

申请号：EP95942858.0

申请日：1995-11-13

申请人： MEDTRONIC, INC.

发明人： YERICH, Charles, G. ,  COMBS, William, J. ,  KLECKNER, Karen, J. ,  PANKEN, Eric, J. ,  SCHALLHORN, Richard, S. ,  WAHLSTRAND, John, D.

IPC分类号： A61N1

CPC分类号： A61N1/36585

摘要： A body-implantable rate-responsive cardiac pacemaker is provided with circuitry for sensing a plurality of physiologic parameters known to be indicative of a patient's metabolic demand for increased cardiac output. In one embodiment, a rate-responsive pacemaker is provided with an activity sensor for detecting the patient's level of physical activity, and is further provided with an impedance sensing circuit for detecting the patient's level of minute ventilation by monitoring cardiac impedance. A rate-response transfer function, implemented by the pacemaker's control circuitry, periodically computes a rate-responsive pacing rate as a function of the outputs from both physiologic sensing circuits. The pacemaker's pacing rate is variable within a rate range defined by predetermined (programmable) upper and lower limits. In the preferred embodiment, the influence of activity sensing and minute ventilation parameters varies in accordance with the current pacing rate. In particular, the influence of activity sensing in rate determination in accordance with the rate-response function is greater than that of minute ventilation, for slower pacing rates, while the influence of minute ventilation sensing dominates over that of activity sensing for higher pacing rates. Rate response operation of the disclosed system is recorded in the form of histogram data stored over a predetermined history time. The relative influence of the activity sensing and minute ventilation sensing on rate determination is periodically scaled or balanced based upon comparison of the histogram data with predetermined desired response data.

公开(公告)号：EP0751804A1

公开(公告)日：1997-01-08

申请号：EP95909480.0

申请日：1995-02-06

申请人： MEDTRONIC, INC.

发明人： KIEVAL, Robert, S. ,  HESS, Michael, F.

IPC分类号： A61N1

CPC分类号： A61N1/056 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3712

摘要： A dual chamber pacemaker and a method of employing the pacemaker to accomplish atrial synchronized ventricular pacing with complete ventricular capture by control of the A-V escape intervals of the pacer. The maximum A-V escape interval effective to accomplish complete ventricular capture is determined and compared to intrinsic A-V conduction time to derive an offset interval. The offset interval is subtracted from the initially measured conduction time to select initial A-V escape interval durations and is subtracted from A-V conduction times measured after implant of the pacemaker to automatically adjust A-V escape interval durations of the pacemaker to maintain complete ventricular capture.

公开(公告)号：EP0741592A1

公开(公告)日：1996-11-13

申请号：EP95909304.0

申请日：1995-01-23

申请人： MEDTRONIC, INC.

发明人： HOLSHEIMER, Jan ,  STRUIJK, Johannes, J.

IPC分类号： A61N1

CPC分类号： A61N1/0551 ,  A61N1/0553 ,  A61N1/36071

摘要： Apparatus for multi-channel transverse epidural spinal cord stimulation uses a multi-channel pulse generator driving a plurality of electrodes mounted near the distal end of a lead. These electrodes are mounted in one or more lines, generally perpendicular to the lead axis, and have a planar surface along one surface of the lead. The lead is implanted adjacent to spinal cord dura mater with the electrodes transverse and facing the spinal cord. Pulses generated by the pulse generator for each channel are normally simultaneous, of equal amplitude and of equal duration, however, the pulse generator is arranged such that pulses for each channel can selectably alternate in time, can selectably be of unequal amplitude, or both. The changes in pulse timing and magnitude permit shifting the electrical stimulation field and the resulting paresthesia pattern after installation to accommodate improper lead placement or postoperative dislocation and to minimize unwanted motor responses.

公开(公告)号：EP0740563A1

公开(公告)日：1996-11-06

申请号：EP95911571.0

申请日：1995-01-20

申请人： MEDTRONIC, INC.

发明人： MEHMANESH, Hormoz ,  SAGGAU, Werner ,  SMITS, Karel F. A. A. ,  DREESSEN, Chrit W.

IPC分类号： A61N1

CPC分类号： A61N1/0587

摘要： A temporary atrial defibrillation lead featuring a pad fashioned of a pliant biocompatible material in which three parallel stainless steel defibrillation wire electrodes are mounted. The pad contains holes which expose the electrode wires in a discontinuous fashion. The three electrode wires are merged into one polyurethane insulated lead body, proximal to the pad. At the proximal end of the lead body a stainless steel connector pin with break away needle is mounted, for percutaneous exteriorization of the lead pin, in an area separated from the surgical incision. The break away needle can be broken off to make the connector pin suitable to patient cable connection. The pad is permanently implanted on the atria and remains implanted after removal of the temporary electrode sections. The temporary electrode sections may be removed by gently pulling them at their proximal end. In a preferred embodiment the pad is fashioned of PTFE felt. In an alternate embodiment the pad is fashioned of collagen and is thereby absorbed by the body tissues over time.

公开(公告)号：EP0722348A1

公开(公告)日：1996-07-24

申请号：EP94926622.0

申请日：1994-08-26

申请人： MEDTRONIC, INC.

发明人： GRANDJEAN, Pierre A. ,  LEINDERS, Robert ,  BOURGEOIS, Ivan

IPC分类号： A61N1 ,  H02J7

CPC分类号： A61N1/3708 ,  A61N1/36042

摘要： An end-of-life (EOL) indicator for an implantable pulse generator (IPG) - especially of the neuromuscular stimulation variety - indicates an approaching battery EOL condition via an electrocardiogram (ECG) by changing the nature of the muscle stimulation burst signals. IPG internal circuitry detects an approaching EOL condition and modifies the burst signals by, for example, decreasing the number of pulses in a burst, increasing the heart contraction-to-powering-muscle contraction ratio, or alternating between two numbers of pulses in successive burst cycles. The approaching battery EOL condition can be easily ascertained via trans-telephonic monitoring by analyzing a transmitted ECG alone, for the above-mentioned burst signal changes. By observing the patterns in the ECG caused by the burst signal changes, a clinician could be aware of an approaching EOL without having known the original muscle stimulation burst signal parameters.

公开(公告)号：EP0706408A1

公开(公告)日：1996-04-17

申请号：EP94921182.0

申请日：1994-05-10

申请人： MEDTRONIC, INC.

发明人： RYAN, Terrence G. ,  BUSACKER, James W. ,  HOCHBAN, Robert A.

IPC分类号： A61N1 ,  H04L25 ,  H04Q9

CPC分类号： A61N1/37252 ,  A61N1/3727 ,  H04L25/4902

摘要： An implantable medical device telemetry system provides a means for decoding telemetry downlink information transmitted from an external unit to an implanted medical device, and for encoding telemetry uplink signals to be transmitted from the implanted device to the external unit. A novel system architecture results in a very small telemetry subsystem in the implanted device and a very flexible system adaptable to be used in conjunction with various telemetry formats of various implanted devices. A programmable logic array (PLA) structure that is mask programmable and which may further be partially RAM programmable serves as the basis of the telemetry subsystem. For downlink telemetry, a counter is enabled during intervals of interest in the downlink RF burst stream. The counter value at the end of such an interval is then applied to the variable inputs of the PLA for decoding in accordance with a selected telemetry protocol. For uplink telemetry, the counter and PLA is used to control transmission of uplink telemetry pulses, such that pulses are pulse-position modulated in accordance with data to be transmitted. Various different telemetry protocols may be supported by the same telemetry circuit, which may be mask-programmed at the time of manufacture to be compatible with one or more different telemetry protocols.

公开(公告)号：EP0689469A1

公开(公告)日：1996-01-03

申请号：EP94910659.0

申请日：1994-01-26

申请人： MEDTRONIC, INC.

发明人： ZIPES, Douglas, P. ,  ULRICH, Clare, P. ,  BLANKENAU, Paul, D. ,  WILLIAMS, Terrell, M.

IPC分类号： A61N1

CPC分类号： A61N1/057

摘要： Apparatus for affixing implantable catheters and leads to body tissue. An electrode located on the lead or catheter is coupled to an RF signal generator, of the type employed to perform electrosurgical procedures such as electrocoagulation. The RF signal causes the electrode to adhere to body tissue, thus stabilizing the location of the catheter or lead. The electrode may be a dedicated electrode employed only for affixation. Contact between the electrode and the RF signal generator may be made by a removable conductor.

公开(公告)号：EP0959942A1

公开(公告)日：1999-12-01

申请号：EP97917832.0

申请日：1997-04-02

申请人： MEDTRONIC, INC.

发明人： RISE, Mark, T. ,  KING, Gary, W.

IPC分类号： A61N1

CPC分类号： A61N1/36067 ,  A61N1/0534

摘要： Techniques for stimulating the brain (B) to treat movement disorders resulting in abnormal motor behavior by means of an implantable signal generator (10) and electrode (115). A sensor (130) is used to detect the symptoms resulting from the motion disorders. A microprocessor algorithm anaylzes the output from the sensor in order to regulate the stimulation delivered to the brain.

公开(公告)号：EP0959914A1

公开(公告)日：1999-12-01

申请号：EP97915120.0

申请日：1997-03-18

申请人： MEDTRONIC, INC.

发明人： PLOTKIN, Neil, D.

IPC分类号： A61M1

CPC分类号： A61M1/3627

摘要： A simple, self-supporting cardiotomy filter/defoamer is formed by a 20 νm cylindrical spray spun hollow plastic filter cartridge impregnated with an anti-foaming agent.