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    CORONAVIRUS VACCINE
    21.
    发明公开
    CORONAVIRUS VACCINE 审中-公开

    公开(公告)号：EP4226938A3

    公开(公告)日：2023-11-01

    申请号：EP22210373.1

    申请日：2022-11-29

    申请人： BioNTech SE

    发明人： MUIK, Alexander ,  PORAN, Asaf ,  SAHIN, Ugur ,  SWANSON, Kena Anne ,  YANG, Qi ,  CAI, Hui

    IPC分类号： A61K39/12 ,  A61P31/14

    摘要： This disclosure relates to the field of RNA to prevent or treat coronavirus infection. In particular, the present disclosure relates to methods and agents for vaccination against coronavirus infection and inducing effective coronavirus antigen-specific immune responses such as antibody and/or T cell responses. Specifically, in one embodiment, the present disclosure relates to methods comprising administering to a subject RNA encoding a peptide or protein comprising an epitope of SARS-CoV-2 spike protein (S protein) for inducing an immune response against coronavirus S protein, in particular S protein of SARS-CoV-2, in the subject, i.e., vaccine RNA encoding vaccine antigen.