Abstract:
A micro-fluidic chamber (1) for use in a liquid medicament delivery system has a bottom substrate (11) and a top cover (12), the top cover (12) being spaced from the bottom substrate (11) so as to define a height (H1) of the chamber (1). One or more walls or fillings (13) are positioned in the chamber (1), the walls or fillings (13) defining a fluid channel (2) there between such that the fluid channel (2) extends from an inlet (21) of the chamber to an outlet (22) of the chamber. Each of the walls or fillings (13) has a height (H2) less than the height (H1) of the chamber (1) so as to define a gap (3) between a top surface (131) of each wall or filling (13) and the top cover (12). The dimensions (H1, H2) of the walls or fillings (13) and the chamber (1) are chosen such that the fluid gap (3) will be filled with liquid (4) by capillary forces via the fluid channel (2) when liquid (4) is introduced into the fluid chamber (1).
Abstract:
Hydrophilic adhesive compositions are disclosed that contain a surfactant that is miscible, but not fully soluble in the polymer matrix of the adhesive. This permits the surfactant to continuously replenish at the surface of the adhesive as other surfactant is removed, such as when it is carried away by an aqueous sample flowing over that surface in an in-vitro diagnostic device, resulting in adhesive compositions that are inherently hydrophilic on their surfaces and do not rely on the bloom mechanism of known hydrophilic adhesives. This provides greater design options for in-vitro diagnostic device manufacturers, including the use of hydrophilic adhesive spacers in lieu of or in combination with hydrophilic top covers.