Antitumor agent and process for manufacturing said agent
    21.
    发明公开
    Antitumor agent and process for manufacturing said agent 失效
    抗菌剂及其制造方法

    公开(公告)号:EP0116232A3

    公开(公告)日:1985-09-18

    申请号:EP83307953

    申请日:1983-12-23

    IPC分类号: C12P01/04 C12R01/01 A61K35/74

    CPC分类号: C12P1/04 C12R1/01

    摘要: This invention relates to an antitumor agent comprising as a main ingredient a chemically purified cell walls of microorganisms belonging to genus Bificobacterium having physical integrity of cell wall structure thereof, obtained without being subjected to chemical and/or physical destruction of said cell wall during removal of intracellular substances of said cell, and a process for manufacturing the same, which comprises the steps of; (a) treating said cells with surfactants, (b) treating said cells with proteases, nucleases, organic solvents and dilute acid, to remove intracellular substances out of said cells without destruction thereof, and (c) separating a chemically purified cell walls having physical integrity of cell wall structure thereof.