摘要:
Novel glycopeptide antibiotics of the CWI-785 complex are produced by the novel actinomycete organism SK&F-CWI-785. The CWI-785 complex may be hydrolyzed and/or the isomers separated to form other novel glycopeptide antibiotics.
摘要:
This invention provides Methylophilus viscogenes as a novel species of facultative methotrophic bacteria. Methylophilus viscogenes strain ATCC 39893. is capable of assimilating methanol via the ribulose monophosphate pathway to form extracellular heteropolysaccharide Poly 54 under aerobic cultivation conditions.
摘要:
Improved method for the purification of filamentous hemagglutinin (F-HA) on industrial scale which comprises contacting a culture of a microorganism of the genus Bordetella with a cellulose sulfate gel, a polysaccharide gel chemically bound with dextran sulfate, or a crosslinked polysaccharide sulfate gel, thereby adsorbing F-HA on the gel, and then eluting F-HA from the gel. Said method can give a highly purified F-HA which does not contain any other proteins, lipid, saccharides, etc. and further undesirable endotoxin, and hence can be used for producing various reagents, medicines and pertussis vaccine.
摘要:
A method for producing L-camitine which comprises contacting crotonbetaine or a salt thereof with a microorganism or fraction of said microorganism which contains the enzymes capable of converting crotonbetaine or salts thereof into L-camitine in an aqueous medium under conditions suitable for the production of L-carnitine.
摘要:
Novel transposable cloning vector and method of using it for the insertion into the chromosome of a receipient Gram-negative bacterium of DNA material foreign to that bacterium. The vector comprises first and second plasmids. The first plasmid carries a transposon (A), a part of whose DNA including the sequence which specifies its transposition function has been removed. The second plasmid carries a fragment of DNA from a transposon (A) including the sequence which specifies its transposition function. The DNA material to be inserted into the chromosome of the recipient bacterium is included in the DNA of transposon (A) carried by the first plasmid. Any suitable transposon may be used as transposon (A) but transposon Tn7 is preferred.
摘要:
A novel water-soluble peptide designated herein as Bu-2517 is produced by fermentation of Empedobacter sp. strain G393-B445 (ATCC 31962). The antibiotic exists in a cyclic depsipeptide structure and contains the amino acids D-serine, D-proline, L-proline, D-threo-β-hydroxyaspartic aicd, L-threo-p-hydroxyaspartic acid, L-arginine and trans-L-3-hydroxyproline and the residue of the C 14 fatty acid, 3-hydroxytetradecanoic acid. The Bu-2517 antibiotic inhibits the growth of a variety of aerobic and anaerobic gram-positive bacteria.
摘要:
Disclosed is a plasmid with wide host range which can self-replicate in a microorganism belonging to the family Enterobacteriaceae. The production of L-threonine may be promoted by using a transformant transformed with a new recombinant DNA obtained by inserting a gene responsible for the production of L-threonine derived from a microorganism belonging to the genus Providencia, to the above plasmid.
摘要:
Die Gewinnung von Fructose bzw. deren Anreicherung gegenüber Glucose ausgehend von einer Fructose und Glu cose enthaltenden wäßrigen Mischung durch fermentativen Glucoseabbau zu Ethanol und Kohlendioxid erfolgt mittels einer durch kontinuierliche Kultur über zumindest 10 Tage, ins besondere 100 Tage erhaltenen stabilen fructose-negativen Mutante von Zymomonas mobilis. Insbesondere wird die bei der Deutschen Sammlung von Mikroorganismen in Göttingen hinterlegte Mutante mit der Hinterlegungsnummer DSM 3126 verwendet. Zuckerkonzentrationen der wäßrigen Ausgangsmi schungen mit je ≧ 1% bzw. je 4 bis 13% und insbesondere je 7,5 bis 10% Glucose und Fructose sind geeignet. Die Fermen tation erfolgt insbesondere kontinuierlich.