公开(公告)号：EP2646798A1

公开(公告)日：2013-10-09

申请号：EP11813674.6

申请日：2011-12-05

申请人： Mindseeds Laboratories S.r.l.

发明人： BOCCHI, Massimo ,  GUERRIERI, Roberto

IPC分类号： G01N15/14 ,  B03C5/00 ,  B03C5/02

CPC分类号： G01N15/1404 ,  B01L3/50273 ,  B01L3/502792 ,  B01L3/5088 ,  B01L2200/0652 ,  B01L2300/0645 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2400/0424 ,  B03C5/005 ,  B03C5/022 ,  B03C5/026 ,  B03C2201/26 ,  C12M23/12 ,  C12M29/10 ,  C12M41/46 ,  G01N1/4077 ,  G01N15/1484 ,  G01N27/44791 ,  G01N33/50 ,  G01N33/5005 ,  G01N2015/1415 ,  G01N2015/1481 ,  G01N2015/149

摘要： An inverted microwell (102) provides rapid and efficient microanalysis system (100) and method for screening of biological particles (128), particularly functional analysis of cells on a single cell basis. The use of an inverted open microwell system (102) permits identification of particles, cells, and biomolecules that may be combined to produce a desired functional effect also functional screening of secreted antibody therapeutic activity as well as the potential to recover cells and fluid, and optionally expand cells, such as antibody secreting cells, within the same microwell.

公开(公告)号：EP1837088B1

公开(公告)日：2013-05-15

申请号：EP06700897.9

申请日：2006-01-13

申请人： Panasonic Corporation

发明人： YASUDA, Issei c/o Matsushita Electric Industrial Co. Ltd., ,  FUKUDA, Ko c/o Matsushita Electric Industrial Co. Ltd.,

IPC分类号： B07B4/02 ,  B03C5/00 ,  B08B5/00 ,  B29B17/02

CPC分类号： B29B17/02 ,  B07B4/02 ,  B07B9/02 ,  B29B2017/0234 ,  B29B2017/0241 ,  B29B2017/0272 ,  B29L2031/3055 ,  B29L2031/3061 ,  Y02W30/524 ,  Y02W30/525 ,  Y02W30/526 ,  Y02W30/622

公开(公告)号：EP2027929A3

公开(公告)日：2013-03-27

申请号：EP08014447.0

申请日：2008-08-13

申请人： Olympus Corporation

发明人： Hakoda, Masaru ,  Yoshida, Satoshi ,  Hibino, Hiroki ,  Fukuda, Hiroshi ,  Shiba, Yoshiaki

IPC分类号： B03C5/02 ,  B03C5/00

CPC分类号： B03C5/026 ,  B03C5/005

摘要： Plural types of cells having different dielectrophoretic properties are separated using a simple structure. There is provided a cell separation device including: a flow path through which a cell suspension flows, the cell suspension containing plural types of cells which have different dielectrophoretic properties; electrodes disposed to face each other in a direction intersecting a flow direction of the cell suspension flowing in the flow path; an electric field gradient forming portion which generates an electric field strength gradient between the electrodes; and a power supply applying an alternating voltage having a direct current component across the electrodes.

公开(公告)号：EP2032262B1

公开(公告)日：2012-02-22

申请号：EP07734717.7

申请日：2007-05-31

申请人： Mindseeds Laboratories S.r.l.

发明人： GUERRIERI, Roberto ,  BOCCHI, Massimo

IPC分类号： B03C5/00 ,  B03C5/02

CPC分类号： B01L3/50273 ,  B01L2200/14 ,  B01L2300/0893 ,  B01L2400/0424 ,  B03C5/005 ,  B03C5/026 ,  G01N27/44782 ,  G01N27/44791

摘要： A well, in particular an open well (14) with an upper end having a vertical axis (101), for containing a liquid and particles contained within said liquid, characterized by comprising at least two manipulation electrodes (1, 2, 3, 31, 32, 36, 17, 40, 41) able to be powered by electrical voltages, in particular alternating electrical voltages, so as to manoeuvre particles within the well by means of the dielectrophoretic effect. A platform comprising a plurality of wells as described above and a method for using said well.

公开(公告)号：EP2310133A1

公开(公告)日：2011-04-20

申请号：EP09784661.2

申请日：2009-07-09

申请人： Blood Analysis Limited

发明人： SALMON, Peter ,  ANTHONY, Robert, Stewart

IPC分类号： B03C5/00 ,  B03C5/02

CPC分类号： B03C5/005 ,  B03C5/026

摘要： A method of collecting, detecting and enumerating microorganisms in a fluid comprising subjecting a sample of the fluid to dielectrophoresis and collecting the microorganisms onto a microelectrode, scanning the microelectrode using a scanning laser and determining the number of microorganisms present on the microelectrode.

公开(公告)号：EP1485191A4

公开(公告)日：2010-08-25

申请号：EP03726025

申请日：2003-03-04

申请人： CALIPER LIFE SCIENCES INC

发明人： CHIEN RING-LING ,  PARCE J WALLACE ,  SPAID MICHAEL

IPC分类号： B01D57/02 ,  B01F13/00 ,  B01L3/00 ,  B03B13/00 ,  B03B13/04 ,  B03C5/00 ,  F04B19/00 ,  G01N27/447 ,  G01N37/00 ,  H02N11/00 ,  B01D57/00

CPC分类号： B01F13/0076 ,  B01L3/502746 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0415 ,  B01L2400/0487 ,  B01L2400/084 ,  F04B19/006 ,  G01N27/44791 ,  H02N11/006

公开(公告)号：EP2134442A1

公开(公告)日：2009-12-23

申请号：EP08731544.6

申请日：2008-03-06

申请人： M-I LLC

发明人： MCCOSH, Karen

IPC分类号： B01D43/00 ,  B03C5/00 ,  E21B21/06

CPC分类号： E21B21/065 ,  C02F1/4696 ,  C02F11/006 ,  C02F2001/46119 ,  C02F2101/301 ,  C02F2103/10 ,  C02F2201/46135 ,  C02F2201/4615 ,  C02F2201/46175 ,  C02F2209/42

摘要： A method of treating an invert emulsion drilling fluid, the method including pumping the drilling fluid to an electrophoresis unit that includes a positively charged electrode and a negatively charged electrode, applying a voltage between 200 V and 5000 V across the two electrodes to deposit water and solids on one of the charged electrodes, and removing deposited solids and water from the collection electrode is disclosed. An apparatus for treating an invert emulsion drilling fluid, the apparatus including a bath, a drum disposed in the bath, a power supply capable of applying a voltage between the housing and the drum in the range of 200 V to 5000 V, a motor coupled to the drum to rotate the drum at a predetermined speed, and a scraper having a first position in which the scraper contacts the rotating drum to remove deposited solids and water and a second position in which the scraper is retained away from the drum is also disclosed.

公开(公告)号：EP1583956A4

公开(公告)日：2009-07-15

申请号：EP03810889

申请日：2003-12-22

申请人： UNIV TEXAS

发明人： GASCOYNE PETER R C ,  VYKOUKAL JODY V ,  DAS CHANDRA ,  BECKER FREDERICK F

IPC分类号： B03C5/00 ,  B03C5/02 ,  G01N20060101 ,  G01N1/28 ,  G01N27/26 ,  G01N27/447

CPC分类号： G01N30/0005 ,  B03C5/005 ,  B03C5/026 ,  B03C2201/24 ,  G01N1/2813 ,  G01N2030/0065 ,  G01N2030/007

摘要： Methods and apparatus for preparing a smear for cytopathology or other analysis. In a representative embodiment, cells of a sample are subjected to a dielectrophoretic force to segregate the cells into two or more zones of a surface. The particles are attached to the surface, thereby defining a “segregated smear”. The segregated smear is then fixed and stained for cytopathology analysis.

公开(公告)号：EP2054158A2

公开(公告)日：2009-05-06

申请号：EP07804714.9

申请日：2007-08-06

申请人： Silicon Biosystems S.p.A.

发明人： MEDORO, Gianni ,  MANARESI, Nicolo'

IPC分类号： B03C5/00 ,  B03C5/02

CPC分类号： B03C5/026 ,  B03C5/005 ,  B03C5/024

摘要： Methods and relative devices are illustrated for generating time-variable electric fields suitable for determining the creation of closed dielectrophoretic cages able to trap inside even single particles without the cages being necessarily positioned at relative minimum points of the electric field.

公开(公告)号：EP2027929A2

公开(公告)日：2009-02-25

申请号：EP08014447.0

申请日：2008-08-13

申请人： Olympus Corporation

发明人： Hakoda, Masaru ,  Yoshida, Satoshi ,  Hibino, Hiroki ,  Fukuda, Hiroshi ,  Shiba, Yoshiaki

IPC分类号： B03C5/02 ,  B03C5/00

CPC分类号： B03C5/026 ,  B03C5/005

摘要： Plural types of cells having different dielectrophoretic properties are separated using a simple structure. There is provided a cell separation device including: a flow path through which a cell suspension flows, the cell suspension containing plural types of cells which have different dielectrophoretic properties; electrodes disposed to face each other in a direction intersecting a flow direction of the cell suspension flowing in the flow path; an electric field gradient forming portion which generates an electric field strength gradient between the electrodes; and a power supply applying an alternating voltage having a direct current component across the electrodes.

摘要翻译： 使用简单的结构分离具有不同介电电泳性质的多种类型的细胞。 提供了一种细胞分离装置，其包括：细胞悬浮液流过的流路，所述细胞悬浮液含有具有不同介电电泳性质的多种细胞; 设置成在与在流路中流动的细胞悬浮液的流动方向相交的方向上彼此面对的电极; 电场梯度形成部，其在所述电极之间产生电场强度梯度; 以及施加具有跨越电极的直流分量的交流电压的电源。