-
公开(公告)号：EP3488026A1
公开(公告)日：2019-05-29
申请号：EP16909734.2
申请日：2016-10-03
-
公开(公告)号：EP3487530A1
公开(公告)日：2019-05-29
申请号：EP17752519.3
申请日：2017-07-25
发明人： WEICHERT, Jamey , SONDEL, Paul, M. , PINCHUK, Anatoly , MORRIS, Zachary , OTTO, Mario , BEDNARZ, Bryan , CARLSON, Peter
IPC分类号： A61K39/395 , A61K51/06
-
公开(公告)号：EP3436422A1
公开(公告)日：2019-02-06
申请号：EP17741766.4
申请日：2017-01-11
IPC分类号： C07C31/20 , C07C29/04 , C07C29/132
-
公开(公告)号：EP2356221B1
公开(公告)日：2018-11-21
申请号：EP09744285.9
申请日：2009-10-23
发明人： THOMSON, James , YU, Junying
CPC分类号： C12N15/85 , C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/605 , C12N2501/606 , C12N2501/608 , C12N2510/00
摘要： Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed.
-
公开(公告)号：EP3370745A1
公开(公告)日：2018-09-12
申请号：EP16790850.8
申请日：2016-10-26
CPC分类号： A61K9/0056 , A23K1/164 , A23K1/188 , A23K10/20 , A23K20/158 , A23K50/80 , A61K31/232 , A61K35/57 , A61K45/06 , Y02A40/818
摘要： Described herein are methods of use of purified preen oil, food and feed compositions containing purified preen oil, food and feed additives containing purified preen oil, and pharmaceutical compositions containing purified preen oil. Methods include treatment of chronic joint inflammation in humans and animals by orally administering purified preen oil. Also included are methods of feeding a growing fish by feeding the feeding the growing fish purified preen oil in amounts effective to improve survival and/or stimulate growth in the growing fish. Further included are methods of feeding live prey organisms purified preen oil, and feeding the live prey organisms to growing fish.
-
36.发明公开
公开(公告)号：EP3362438A1
公开(公告)日：2018-08-22
申请号：EP16856326.0
申请日：2016-10-14
发明人： LI, Lingjun , FROST, Dustin , BUCHBERGER, Amanda
IPC分类号： C07D239/08 , C07D239/14 , G01N27/62 , G01N33/50 , G01N33/68
CPC分类号： G01N33/6848 , C07D239/42 , G01N33/6812 , G01N2458/15
摘要： The use of mass defect signatures to impart milliDalton mass differences between isotopically labeled peptides at the MS1-level allows multiplex quantification without the increased mass spectral complexity that occurs with mass difference approaches. Provided herein is a mass defect-based chemical tag, dimethyl pyrimidinyl ornithine (DiPyrO), that is compact and easy to synthesize at high purity in few steps using commercially available starting materials. The multiplex DiPyrO tags are amine-reactive and can impart a mass difference onto labeled peptides and through calculated substitution of heavy isotopes. DiPyrO offers up to 10-plex quantification on current Orbitrap or FT-ICR platforms without increasing mass spectral complexity. The synthesis of the DiPyrO tag is provided along with viability of the DiPyrO tag for labeling complex proteomics samples using yeast extract digests and its effect on labeled peptides during LC-MS2 analysis. Labeling and quantification of glycans and metabolites using the DiPyrO tag is also demonstrated.
-
公开(公告)号：EP2207901B1
公开(公告)日：2018-07-25
申请号：EP08839468.9
申请日：2008-10-17
发明人： SCHWARTZ, David, C. , POTAMOUSIS, Konstantinos, D. , ZHOU, Shiguo , GOLDSTEIN, Steven, J. , NEWTON, Michael, A. , RUNNHEIM, Rodney, A. , FORREST, Daniel, K. , CHURAS, Christopher, P.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6869 , C12Q2535/101
摘要： Methods are provided for ascertaining the sequence of a genomic DNA sample by nicking the DNA sample with a restriction nicking enzyme, followed by nick translation with labeled nucleotides, such that the labeled nucleotides can be quantified and compared to a known, reference genome.
-
38.发明公开
公开(公告)号：EP3347198A1
公开(公告)日：2018-07-18
申请号：EP16757808.7
申请日：2016-08-18
发明人： ABBOTT, Nicholas , JAIN, Rishabh , NELSON, Kevin , BUSCHE, David , LYNN, David
IPC分类号： B32B7/00 , B32B7/02 , B32B7/10 , B32B7/12 , B32B27/00 , B32B27/06 , B32B27/18 , B32B27/28 , B32B27/30 , B32B27/32 , B32B27/34 , B32B27/36 , B32B1/00 , C01B11/02 , C01B7/01 , C01B13/10 , A01N59/00 , A01N59/02 , A23L3/3409
CPC分类号： A61L2/20 , A23B7/144 , A61L2202/11 , B01J19/123 , B01J2219/0879 , B01J2219/1203 , B32B1/02 , B32B7/02 , B32B7/12 , B32B15/08 , B32B15/082 , B32B15/085 , B32B15/20 , B32B27/08 , B32B27/18 , B32B27/20 , B32B27/28 , B32B27/30 , B32B27/304 , B32B27/306 , B32B27/32 , B32B27/322 , B32B27/34 , B32B27/36 , B32B2255/10 , B32B2255/20 , B32B2255/205 , B32B2264/10 , B32B2307/40 , B32B2307/50 , B32B2307/71 , B32B2307/7242 , B32B2307/7244 , B32B2307/7246 , B32B2307/732 , B32B2307/748 , B32B2315/00 , B32B2323/10 , B32B2405/00 , B32B2439/06 , B32B2439/46 , B32B2439/70 , B32B2439/80 , B65D1/00 , B65D65/40 , B65D81/24 , C01B11/024 , C08K3/24 , C08L23/12 , C08L2203/16
摘要： A multilayer produce packaging film includes a first layer and a chlorine dioxide-producing layer. The chlorine dioxide-producing layer includes a polymer composition and a plurality of chlorite ions. The chlorine dioxide-producing layer is substantially free of an energy-activated catalyst and is substantially free of an acid-releasing compound. However, the film is capable of generating chlorine dioxide when exposed to UV light and moisture.
-
公开(公告)号：EP3307264A1
公开(公告)日：2018-04-18
申请号：EP16730223.1
申请日：2016-06-10
发明人： KWON, Glen , TOMODA, Keishiro , KOZAK, Kevin
IPC分类号： A61K31/337 , A61K31/436 , A61K9/10 , A61P35/00
CPC分类号： A61K31/337 , A61K9/1075 , A61K9/19 , A61K31/395 , A61K31/436 , A61K47/34 , A61K2300/00 , A61P35/00
摘要： Provided is a method of treatment including administering to lung, brain or esophageal cancer cells an effective amount of radiation in conjunction with a micelle composition that includes an effective amount of paclitaxel, and one or both of 17-AAG, and rapamycin, wherein the micelle includes poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA).
-
40.发明授权TOPICAL VASOCONSTRICTOR PREPARATIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY 有权癌症化疗和放射治疗过程中保护细胞的局部血管生成制剂和方法
公开(公告)号：EP1890732B1
公开(公告)日：2018-03-28
申请号：EP06773476.4
申请日：2006-06-19
IPC分类号： A61K31/137 , A61K9/00 , A61P43/00
CPC分类号： A61K31/137 , A61K9/0014 , A61K9/006 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/20
摘要： Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages and formulations of topical vasoconstrictors are provided. Methods for the use of such compositions are also provided.
-
-
-
-
-
-
-
-
-
搜索结果
1496 条记录 (耗时 0.023 秒)
