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公开(公告)号：EP3613427A1
公开(公告)日：2020-02-26
申请号：EP19202000.6
申请日：2014-08-04
IPC分类号： A61K38/17 , A61K39/00 , C07K7/06 , C12N5/0783 , C12N9/64
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to more than 70 novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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公开(公告)号：EP3456339A2
公开(公告)日：2019-03-20
申请号：EP18201334.2
申请日：2014-08-04
IPC分类号： A61K38/17 , A61K39/00 , C07K7/06 , C12N5/0783
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to more than 70 novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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公开(公告)号：EP3426281A1
公开(公告)日：2019-01-16
申请号：EP17709931.4
申请日：2017-03-02
发明人： MAHR, Andrea , WEINSCHENK, Toni , SONG, Colette , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet
IPC分类号： A61K38/17 , A61K39/00 , C07K7/06 , C12N5/0783
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34.发明公开
公开(公告)号：EP3423085A1
公开(公告)日：2019-01-09
申请号：EP17707843.3
申请日：2017-02-28
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公开(公告)号：EP3066115A2
公开(公告)日：2016-09-14
申请号：EP14792834.5
申请日：2014-11-03
发明人： WEINSCHENK, Toni , FRITSCHE, Jens , WALTER, Steffen , HILF, Norbert , SCHORR, Oliver , SINGH, Harpreet , KUTTRUFF-COQUI, Sabrina , SONG, Colette
CPC分类号： A61K39/0011 , A61K35/17 , A61K38/1764 , A61K2039/5158 , A61K2039/572 , C07K7/06 , C07K7/08 , C07K14/4748 , C07K14/705 , C07K14/70539 , C07K16/2833 , C07K2319/33 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
摘要翻译： 本发明涉及用于免疫治疗方法的肽，核酸和细胞。 特别地，本发明涉及癌症的免疫治疗。 本发明还涉及肿瘤相关的细胞毒性T细胞（CTL）肽表位，其单独或与作为刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分的其它肿瘤相关肽的组合。 本发明涉及可用于引发抗肿瘤免疫应答的疫苗组合物中的HLA I类和II类分子的肽序列及其变体。
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36.发明公开NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS, SUCH AS LUNG CANCER, INCLUDING NSCLC 审中-公开神经细胞免疫缺陷病毒（GEMEN），维生素E（VERSCHIEDENE TUMOREN WIE LUNGENKREBS，EINSCHLIESSLICH NSCLC）
公开(公告)号：EP3030255A1
公开(公告)日：2016-06-15
申请号：EP14750175.3
申请日：2014-08-04
IPC分类号： A61K38/17 , A61K39/00 , C07K7/06 , C12N5/0783
CPC分类号： A61K39/0011 , A61K38/1709 , A61K45/06 , A61K2039/5158 , A61K2039/572 , C07K7/06 , C07K7/08 , C07K14/7051 , C12N5/0638 , C12N9/6491 , C12N2502/11 , C12Y304/24065
摘要： The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to more than 70 novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
摘要翻译： 本发明涉及用于免疫治疗方法的肽，核酸和细胞。 特别地，本发明涉及癌症的免疫治疗。 本发明还涉及肿瘤相关的细胞毒性T细胞（CTL）肽表位，其单独或与作为刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分的其它肿瘤相关肽的组合。 本发明涉及可用于引发抗肿瘤免疫应答的疫苗组合物中的70多种新型肽序列及其衍生自人类肿瘤细胞的HLA I类和HLA II类分子的变体。
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