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31.发明公开Solid pharmaceutical dosage forms for reducing the bioavailability food effect 审中-公开一种固体药物剂型的食物效应的生物利用度的减少
公开(公告)号：EP1681052A1
公开(公告)日：2006-07-19
申请号：EP06250256.2
申请日：2006-01-18
发明人： Mohan, Mailatur Sivaraman c/o No.508 5th Floor , Bhushan, Indu , Pergament, Edward D. , Bhagwatwar, Harshal Prabhakar c/o Plot 5 9
CPC分类号： A61K9/2886 , A61K9/2846 , A61K9/2866 , A61K9/2873 , A61K9/5026 , A61K9/5042 , A61K9/5052 , A61K9/5073 , A61K31/4439
摘要： A method of treatment to avoid bioavailability food effects and improve bioavailability variability, by administering a pharmaceutical dosage form containing a pharmaceutical active agent and a disintegrant in a core, a swellable coating surrounding the core, and an optional enteric coating surrounding the swellable coating.
摘要翻译： 治疗的方法，以避免食品的生物利用度的效果和提高的生物利用度可变性，通过施用药物剂型含有药用活性剂和在核心的崩解剂，围绕所述芯的溶胀性涂层，并且可选地围绕所述可溶胀涂层肠溶包衣。
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32.发明公开NOVEL COMPOUNDS AND THEIR USE IN MEDICINE: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 审中-公开新VERBUNDUNGEN及它们在药物：其制备方法和药物制剂
公开(公告)号：EP1678128A1
公开(公告)日：2006-07-12
申请号：EP04706247.6
申请日：2004-01-29
发明人： GURRAM, Ranga, Madhavan Discovery Research , BHUNIYA, Debnath Discovery Research , DAS, Saibal, Kumar Discovery Research , CHAKRABARTI, Ranjan Discovery Research , IQBAL, Javed Discovery Research , SHARMA, Sudhir, Kumar Discovery Research
IPC分类号： C07C323/09 , C07C69/708 , C07C67/14 , C07B57/00 , A61K31/22
CPC分类号： C07C69/757 , C07B2200/07 , C07C33/28 , C07C59/68 , C07C67/30 , C07C67/31 , C07C69/712 , C07C217/84 , C07C309/66 , C07C323/52 , C07C2601/08 , C07C2603/18 , C07D233/64 , C07D265/38 , C07D279/22
摘要： The present invention relates to novel hypolipidemic, antiobesity, hypocholesterolemic and antidiabetic compounds. More particularly, the present invention relates to novel alkyl carboxylic acids of the general formula (I), their stereoisomers, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing them where all symbols are as defined in the description.
摘要翻译： 本发明涉及新的降血脂，抗肥胖，血胆固醇过少和抗糖尿病化合物。 更具体地，本发明涉及含有它们的通式（I）其立体异构体，其药学上可接受的盐的新颖的烷基羧酸，并且其中所有的符号如说明书中所定义的药物组合物。
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公开(公告)号：EP1651193A2
公开(公告)日：2006-05-03
申请号：EP04778421.0
申请日：2004-07-16
发明人： SRINIVAS, Irukulla, Dr. Reddy's Laboratories, Ltd. , DIXIT, Akhilesh A., , Dr. Reddy's Laboratories,Ltd , REDDY, Pallempalli V.S., , Dr. Reddy's Labs., Ltd. , REDDY, Billa P., , Dr. Reddy's Laboratories, Ltd. , MOHAN, Mailatur S., Dr.Reddy's Laboratories, Ltd. , RAVINDER, Kodipyaka, Dr.Reddy's Laboratories, Ltd. , NASARE, Vijay, Dr.Reddy's Laboratories, Ltd. , PERGAMENT, Edward, D.
IPC分类号： A61K9/28 , A61K31/4439
CPC分类号： A61K9/5073 , A61K9/2846 , A61K9/2866 , A61K9/2873 , A61K9/2886 , A61K9/5026 , A61K9/5042 , A61K9/5052
摘要： A pharmaceutical dosage form containing a pharmaceutical active that is not stable in the presence of acid comprises a core containing the active and a disintegrant, a swellable coating surrounding the core, and an enteric coating surrounding the swellable coating.
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公开(公告)号：EP1648422A2
公开(公告)日：2006-04-26
申请号：EP04779390.6
申请日：2004-07-28
发明人： SASMAL, Badal Kumar, Dr. Reddy's Laborat. Ltd. , REDDY, Billa Praveen, Dr. Reddy's Labor. Ltd. , NASARE, Vijay Dinanathji, Dr. Reddy's Labor. Ltd. , MOHAN, Mailatur Sivaraman, Dr. Reddy's Labor. Ltd.
CPC分类号： A61K9/209 , A61K9/4808 , A61K31/165 , A61K31/225 , A61K31/366 , A61K31/401 , A61K31/549 , A61K31/616 , A61K45/06 , A61K2300/00
摘要： A pharmaceutical dosage form for treating or preventing cardiovascular events comprises therapeutic amounts of: a ?-adrenergic receptor antagonist, a diuretic, or both; a cholesterol-lowering agent; an inhibitor of the renin-angiotensin system; and aspirin.
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35.发明公开ORAL PHARMACEUTICAL FORMULATIONS COMPRISING ACID-LABILE ACTIVE INGREDIENTS AND A WATER-SOLUBLE SUGAR DERIVATE, USE THEREOF AND THE SUITABLE PROCESS FOR MANUFACTURING THESE 审中-公开口服药物制剂酸不稳定剂和生产过程中的水溶性衍生物，使用及SUITABLE
公开(公告)号：EP1617842A1
公开(公告)日：2006-01-25
申请号：EP04760093.7
申请日：2004-04-22
发明人： KOLHE, Ujwal, Damu , KRISHNA, Divi, Murali , DIXIT, Akhilesh, Ashok , DESHMUKH, Abhijit, Mukund , RAJPUT, Narayan, Daga , MOHAN, Mailatur, Sivaraman , REDDY, Manne, Satyanarayana , KUMAR, Muppa, Kishore , PURENDER, Koilkonda , REDDY, Alieti, Sanjay
IPC分类号： A61K31/4439 , A61K9/20 , A61K9/28 , A61K9/48 , A61P1/04
CPC分类号： A61K9/2886 , A61K9/2018 , A61K9/2846 , A61K31/4439
摘要： An oral pharmaceutical formulation in dosage form comprising and acid-labile compound, a water-soluble sugar and optionally organic base, use of that formulation for the manufacture of a medicament to inhibit gastric secretion and a process for the production are described.
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36.发明公开AMORPHOUS HYDRATES OF ESOMEPRAZOLE MAGNESIUM AND PROCESS FOR THE PREPARATION THEREOF 审中-公开埃索美拉唑镁非晶水合物及其方法
公开(公告)号：EP1546131A1
公开(公告)日：2005-06-29
申请号：EP03791960.2
申请日：2003-08-28
发明人： REDDY, Manne Satyanarayana , KUMAR, Muppa Kishore , PURANDHAR, Koilkonda , REDDY, Bairy, Kondal
IPC分类号： C07D401/12 , A61K31/44
CPC分类号： C07D401/12 , A61K31/44
摘要： A hydrate of esomeprazole magnesium in the form of an amorphous solid is provided. Methods of preparation and use of, as well as formulation containing the hydrate of esomeprazole magnesium in the form of an amorphous solid are also provided.
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37.发明公开NOVEL PHARMACEUTICAL COMPOSITIONS FOR ANTIHISTAMINIC-DECONGESTANT COMBINATION AND METHOD OF MAKING SUCH COMPOSITIONS 有权包括抗组胺剂减充血剂药物组合和方法及其制造的药物组合物
公开(公告)号：EP1490034A1
公开(公告)日：2004-12-29
申请号：EP02722540.8
申请日：2002-04-04
发明人： KAMALAKAR, Talasila,Dr. Reddy's Laboratories Ltd. , DASH, Debashis,Dr. Reddy's Laboratories Ltd. , SRINIVAS, Irukula,Dr. Reddy's Laboratoris Ltd. , DHANORKAR, Vipin T.,Dr. Reddy's Laboratories Ltd. , MOHAN, Mailatur S.,Dr. Reddy's Laboratories Ltd.
IPC分类号： A61K9/20 , A61K31/495 , A61K31/445
CPC分类号： A61K9/209 , A61K31/445 , A61K31/495 , A61K45/06 , A61K2300/00
摘要： The present invention relates to pharmaceutical compositions of antihistamine-decongestant combination. Specifically the invention relates to bilayered tablet formulation comprising antihistaminic decongestant combination. More specifically present invention relates to the novel polymorph of fexofenadine or pharmaceutically accepted salts thereof, with at least one decongestant in the form of bilayered tablet. The preferred polymorphs are polymorph A and polymorph X of fexofenadine hydrochloride.
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38.发明公开NOVEL CRYSTALLINE FORM OF 5-(4-((3-METHYL-4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)METHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE POTASSIUM SALT 审中-公开（ - （（3-甲基-4-氧代-3,4-二氢喹唑啉-2-基）甲氧基）苄基4）噻唑烷-2,4-二酮钾盐5的新结晶形式
公开(公告)号：EP1487830A1
公开(公告)日：2004-12-22
申请号：EP03744465.0
申请日：2003-03-14
发明人： POTLAPALLY, Rajender K.,Custom Chemical Services , SRISILLA, Raju,Custom Chemical Services , MAMILLAPALLI, R.S.,Custom Chemical Services , GADDAM, Om, ReddyCustom Chemical Services
IPC分类号： C07D417/12 , A61K31/505 , A61P3/10
CPC分类号： C07D417/12
摘要： The present invention relates to novel crystalline Form of 5-[4-[[3-methyl-4-oxo-3,4-dihydroquinazolin-2-yl]methoxy]benzyl] thiazolidine -2,4-dione potassium salt having the formula (I). The invention also relates to a pharmaceutical composition comprising the novel crystalline Form and a pharmaceutically acceptable carrier. The novel crystalline Form of the present invention is more active, as an antidiabetic agent than the hitherto known 5-[4-[[3-methyl-4-oxo-3,4-dihydroquinazolin-2-yl]methoxy]benzyl]thiazolidine-2,4-dione potassium salt
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39.发明授权HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES 失效杂环化合物，PROCESS FOR THEIR药物组合物含有它们的它们在相关疾病和糖尿病的治疗
公开(公告)号：EP0958296B1
公开(公告)日：2003-07-30
申请号：EP97934041.1
申请日：1997-06-30
发明人： LOHRAY, Vidya, Bhushan , LOHRAY, Braj, Bhushan , PARASELLI, Rao, Bheema , GURRAM, Ranga, Madhavan , RAMANUJAM, Rajagopalan , CHAKRABARTI, Ranjan , PAKALA, Sarma, K., S.-D1, Raghava Apartments
IPC分类号： C07D417/12
CPC分类号： C07D239/36 , C07D239/47 , C07D239/88 , C07D277/34 , C07D413/12 , C07D417/12 , C07D471/04 , C07D495/04
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公开(公告)号：EP3464297B1
公开(公告)日：2023-10-25
申请号：EP17802297.6
申请日：2017-05-25
发明人： SAI, Sudhir , BASU, Debjit , SARVESH, Kumar , NEELAM, Uday Kumar , MANDAL, Amit Kumar , BANDICHHOR, Rakeshwar , DAHANUKAR, Vilas Hareshwar
IPC分类号： C07D519/00
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