摘要:
The present invention provides a resist composition containing a compound represented by the general formula (1) or (2), a method for forming a resist pattern using the composition, a polyphenolic compound for use in the composition, and an alcoholic compound that can be derived therefrom. wherein R 1 are each independently a single bond or a 2n-valent hydrocarbon group having 1 to 30 carbon atoms wherein the hydrocarbon group may have a cyclic hydrocarbon group, a double bond, a heteroatom, or an aromatic group having 6 to 30 carbon atoms; R 2 are each independently a hydrogen atom, a halogen atom, a linear, branched, or cyclic alkyl group having 1 to 10 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkenyl group having 2 to 10 carbon atoms, or a hydroxyl group and may be the same or different on the same naphthalene ring; at least one of R 2 is a hydroxyl group; n is an integer of 1 to 4; the structural formulas of the repeating units in the formulas (1) and (2) may be the same or different; in the general formula (1), m 1 are each independently an integer of 1 to 7; and in the general formula (2), X are each independently an oxygen atom or a sulfur atom, and m 2 are each independently an integer of 1 to 6.
摘要:
There is described herein antagonists of α4β7 integrin, and more particularly to cyclic peptide antagonists. Accordingly, there is described herein a compound of formula (I) wherein R1, R2, R3, R4, R5, R6, R7 and R8 are various substituents; stereocentres 1*, 2* and 3* are each independently selected from R and S; n is 1, 2, 3, or 4 and where n is 2-4, Z is an amino terminus of an amino acid; -C=0- adjacent L is the carboxy terminus of an amino acid; and L along with Z and -C=0- is a peptide.
摘要:
The invention relates to y-amaninamide (1; x = 0, 1 or 2), y-amaninamidic acid (2; x = 0, 1 or 2), and γ-amaninamidic hydroxamic acid (3; x = 0, 1 or 2), novel derivatives of γ-amanitin (4), and methods and novel building blocks for the synthesis thereof.
摘要:
Provided is a method for producing a compound which is excellent in reaction rate (having higher reaction rate). A method for producing a compound comprising a step of supplying a compound (1) having at least one atom group selected from Group A, a compound (2) having at least one group selected from Group B, a transition metal catalyst, an organic base and a compound having two or more hydroxyl groups into a reaction vessel, and a step of, in the reaction vessel, reacting the compound (1) with the compound (2) in the presence of the transition metal catalyst, the organic base and the compound having two or more hydroxyl groups. a chlorine atom, a bromine atom, an iodine atom or the like, a group represented by -B(R C2 ) 2 , a group represented by -B(OR C2 ) 2 or the like. (wherein, R C2 represents a hydrogen atom, an alkyl group or the like. The plurality of R C2 may be the same or different and may be combined together to form a ring together with a boron atom or an oxygen atom to which they are attached.)
摘要:
The present invention provides an organic EL device having at least an anode, a hole injection layer, a first hole transport layer, a second hole transport layer, a luminous layer, an electron transport layer, and a cathode in order of description. The second hole transport layer includes an arylamine compound having a specific structure, and the electron transport layer includes a pyrimidine derivative having a specific structure. The organic EL device of the present invention has a high efficiency, a low driving voltage, and a longer life.
摘要:
The compounds induce FOXO1 transcription factor translocation to the nucleus by modulating PP2A and, as a consequence, exhibit anti-proliferative effects. They are useful in the treatment of a variety of disorders, including as a monotherapy in cancer treatment, or used in combination with other drugs to restore sensitivity to chemotherapy where resistance has developed.