Shutter assembly
    32.
    发明公开
    Shutter assembly 失效
    快速装配

    公开(公告)号:EP0273671A3

    公开(公告)日:1990-06-06

    申请号:EP87311258.5

    申请日:1987-12-21

    CPC classification number: G01N21/253 G01N2201/0446 G02B5/005

    Abstract: A shutter assembly for selectively allowing fluid or radiation through an aperture positioned at a selected aperture position chosen out of a plurality of potential aperture positions. The assembly comprises a plurality of shutter leaves (20 to 26) sandwiched between a bottom plate (18) and top plate (19). Shutter leaves (20 to 22) are constrained to move between just two positions in a first (Y) direction and leaves (23 to 26) are constrained to move between just two positions in a second (X) direction. Each leaf is formed with a pattern of apertures arranged in such a way as to align with certain apertures in other shutter leaves so that, for at least some combinations of the possible positions of the various shutter leaves, at least one aperture in each shutter is in alignment to thereby provide at least one through-­aperture from one side of the shutter to the other.

    Abstract translation: 一种快门组件,用于选择性地允许流体或辐射通过定位在从多个潜在孔径位置中选择的选定孔径位置的孔。 组件包括夹在底板(18)和顶板(19)之间的多个活门叶(20至26)。 快门叶(20至22)被限制为在第一(Y)方向上的两个位置之间移动并且叶(23至26)被限制为在第二(X)方向上在两个位置之间移动。 每个叶片形成有孔,其以与其他快门叶片中的某些孔对准的方式布置,使得对于各个快门叶片的可能位置的至少一些组合,每个快门中的至少一个孔径是 从而从快门的一侧向另一侧提供至少一个通孔。

    Photo densitometer
    33.
    发明公开
    Photo densitometer 失效
    照片密度计

    公开(公告)号:EP0221779A3

    公开(公告)日:1989-10-11

    申请号:EP86308483.6

    申请日:1986-10-30

    CPC classification number: G01N21/253 G01N2201/0446 G01N2201/0621

    Abstract: An automated vertical photo densitometer for reading solutions contained in microwell plates. The densitometer utilizes an optical system for minimizing the optical effect of a meniscus on the fluid sample. The invention also discloses a method for determining a centrally located position of a microwell beneath an interrogating beam of light by controlling the size of the light beam and by stepping the well through the beam. A measurement of the light intensity received by a detector is taken at each step. A maximum light intensity value is selected as corresponding to a well position wherein a central area of the fluid sample is substantially within the interrogating beam.

    Plate reader
    34.
    发明公开
    Plate reader 失效
    平板阅读器

    公开(公告)号:EP0245920A3

    公开(公告)日:1989-06-28

    申请号:EP87301660.4

    申请日:1987-02-25

    CPC classification number: G01N21/253 G01N2201/0446

    Abstract: A small, compact plate reader is disclosed for microtitre plates. The reader comprises a totally enclosed housing (19), means e.g. a drawer (2) for receiving and inserting into the housing a microtitre plate (7) which is received into the housing between a light source and a photodetector positioned in vertical alignment above and below the microtitre plate. The light source and detector are mounted on a carriage movable in the housing along each of two orthogonal axes by means of the manual control knobs (10, 11) on either side of the housing. The light source and detector are thus positionable with each of the wells of the microtitre plate in turn enabling absorbancy measurements to be made, and visually displayed by a digital display (9). A window (8) in the housing (1) marked with indices corres­ponding to the cells in the microtitre plate permits a visual indication of the position of the detector head relative to the microtitre plate, for example, by illumination from below of the appropriate index mark by the light source itself, or by a secondary light source.

    Abstract translation: 公开了一种用于微量滴定板的小型紧凑型读板器。 读取器包括全封闭壳体(19), 一个用于接收和插入壳体中的微量滴定板(7)的抽屉(2),该微量滴定板(7)被容纳在光源和位于微量滴定板上方和下方的垂直方向上的光电检测器之间的壳体内。 光源和检测器通过壳体两侧的手动控制旋钮(10,11)安装在可沿两个正交轴线的壳体内移动的支架上。 因此,光源和检测器因此可以与微量滴定板的每个孔定位,从而使得能够进行吸光度测量,并由数字显示器(9)可视地显示。 在壳体(1)中的窗口(8)中标有与微量滴定板中的细胞相对应的指标,允许例如通过从适当指数的下方照射检测器头相对于微量滴定板的位置的视觉指示 由光源本身或二次光源标记。

    Fluorometer
    37.
    发明公开
    Fluorometer 失效
    荧光。

    公开(公告)号:EP0108524A1

    公开(公告)日:1984-05-16

    申请号:EP83306179.9

    申请日:1983-10-12

    Inventor: Nelson, Keith E.

    CPC classification number: G01N21/6452 G01N2021/6476 G01N2201/0446

    Abstract: A sensitive frontal approach fluorometer, suitable for measuring the fluorescence of samples in open top microtest wells (20), has an optical system (14) for (a) directing an exciting light downwardly into the well's open top fluorescently to excite the sample and (b) detecting the sample's emitted light which passes upwardly through the well's open top.

    ARRAY LEVEL FOURIER PTYCHOGRAPHIC IMAGING
    38.
    发明公开
    ARRAY LEVEL FOURIER PTYCHOGRAPHIC IMAGING 审中-公开
    ARRAY LEVEL FOURIER人像摄影

    公开(公告)号:EP3251144A1

    公开(公告)日:2017-12-06

    申请号:EP16744002.3

    申请日:2016-01-26

    Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.

    METHOD AND APPARATUS FOR BACTERIAL MONITORING
    40.
    发明公开
    METHOD AND APPARATUS FOR BACTERIAL MONITORING 审中-公开
    方法和仪器监测细菌

    公开(公告)号:EP2981814A4

    公开(公告)日:2016-11-23

    申请号:EP14773472

    申请日:2014-03-25

    Abstract: A system for detecting target elements such as bacteria in a host analyte, comprising a substrate with an ordered array of wells having diameters to fit the size of the targets. The substrate may be a periodic macro-PSi array structure (MPSiAS) illuminated with a broadband source. The reflected light spectrum diffracted from the substrate is optically analyzed to provide the effective optical depth of the wells. Fast Fourier Transform analysis may be used for the optical analysis. Entry of target elements into wells is detected by the change in the effective optical depths of the wells. Micro-organisms as large as bacteria and viruses having dimensions comparable with the wavelength of the illumination can thus be detected. Wells with an inner section impenetrable by the target cells enables compensation for environmental changes. The detection may be performed in real time, such that production line bacterial monitoring may be achieved.

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