公开(公告)号：EP3442947A1

公开(公告)日：2019-02-20

申请号：EP17720921.0

申请日：2017-04-17

申请人： Epizyme Inc

发明人： CAMPBELL, John Emmerson ,  DUNCAN, Kenneth William ,  FOLEY, Megan Alene ,  HARVEY, Darren Martin ,  KUNTZ, Kevin Wayne ,  MILLS, James Edward John ,  MUNCHHOF, Michael John

IPC分类号： C07D231/38 ,  C07D401/12 ,  C07D239/48 ,  A61K31/505 ,  A61K31/506 ,  A61K31/44 ,  A61P7/06 ,  A61P35/02

公开(公告)号：EP3425449A2

公开(公告)日：2019-01-09

申请号：EP18173671.1

申请日：2018-05-22

申请人： Samsung Display Co., Ltd

发明人： PARK, Seunghyun ,  SONG, Junho

IPC分类号： G02F1/1335 ,  G02F1/139

摘要： A display device comprises a liquid crystal display panel comprising a first substrate, a second substrate facing the first substrate and comprising a reflective layer, and a liquid crystal layer disposed between the first and second substrates, a light control member disposed on the liquid crystal display panel and comprising a first optical part, and a polarizing member disposed on the light control member and comprising a polarizer. The liquid crystal layer comprises a first liquid crystal molecule adjacent to the first substrate, and a long axis of the first liquid crystal molecule projected on the first substrate is aligned in a first direction. An extending direction of a long axis of the first optical part projected on the first substrate is parallel to the first direction, and the polarizer has a transmission axis extending in a second direction.

公开(公告)号：EP3386513A2

公开(公告)日：2018-10-17

申请号：EP16820418.8

申请日：2016-12-07

申请人： Epizyme Inc

发明人： BLAKEMORE, Stephen ,  DAIGLE, Scott Richard

IPC分类号： A61K31/5377 ,  C12Q1/68 ,  A61P35/02

CPC分类号： A61K31/5377 ,  C12Q1/6886 ,  C12Q2600/106

摘要： The disclosure provides a method of treating cancer in a subject in need thereof including administering to the subject a therapeutically-effective amount of an enhancer of a zeste homolog 2 (EZH2) inhibitor. In certain embodiments of this method, the subject has one or more mutations in one or more sequences encoding a gene listed in Tables 1-9, Tables 17-19, and/or Figures 19-22.

公开(公告)号：EP3127906B1

公开(公告)日：2018-07-04

申请号：EP16168481.6

申请日：2016-05-05

申请人： Samsung Display Co., Ltd.

发明人： JEONG, Eunjae ,  KIM, Youngkook ,  PARK, Junha ,  SIM, Munki ,  LEE, Eunyoung ,  LEE, Hyoyoung ,  HWANG, Seokhwan

IPC分类号： C07D405/14 ,  C07D409/14 ,  C07D307/92 ,  H01L51/00

CPC分类号： H01L51/0073 ,  C07D307/77 ,  C07D307/92 ,  C07D405/14 ,  C07D409/14 ,  H01L27/3244 ,  H01L51/0052 ,  H01L51/0067 ,  H01L51/0077 ,  H01L51/5056 ,  H01L51/5072

摘要： An organic light-emitting device comprising: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer comprising a compound represented by Formula 1. The organic light-emitting device comprising the compound of Formula 1 may have high efficiency, low driving voltage, high brightness, and long lifespan characteristics.

公开(公告)号：EP2538484B1

公开(公告)日：2018-06-13

申请号：EP12150094.6

申请日：2012-01-03

申请人： Samsung SDI Co., Ltd.

发明人： Kim, Hee-Joong ,  Ishida, Sumihito ,  Song, Eui-Hwan

IPC分类号： H01M10/0525 ,  H01M4/133 ,  H01M4/587 ,  H01M4/583 ,  H01M4/02

CPC分类号： H01M4/587 ,  H01M4/133 ,  H01M4/583 ,  H01M10/0525 ,  H01M2004/021 ,  H01M2004/027

摘要： A carbon-based material having a FWHM ranging from 2.5° to 6.0° at 2¸ ranging from 20° to 30°in an XRD pattern using CuK± ray and a peak area ratio ranging from 1,0 to 100.0 between a peak at 2¸ ranging from 20° to 30° and a peak at 2¸ ranging from 50° to 53°. The invention also relates to a method of manufacturing the carbon-based material, and a negative electrode and a rechargeable lithium battery including the same.

公开(公告)号：EP3323820A1

公开(公告)日：2018-05-23

申请号：EP17188797.9

申请日：2012-02-28

申请人： Epizyme, Inc.

发明人： KUNTZ, Kevin, Wayne ,  OLHAVA, Edward, James ,  CHESWORTH, Richard ,  DUNCAN, Kenneth, William

IPC分类号： C07D471/04 ,  C07D413/14 ,  C07D401/14 ,  A61K31/4738 ,  A61P35/00

CPC分类号： C07D401/12 ,  A61P35/00 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D413/14 ,  C07D471/04

摘要： The present invention relates to substituted 6,5-fused bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof.

公开(公告)号：EP3303286A1

公开(公告)日：2018-04-11

申请号：EP16804352.9

申请日：2016-06-01

申请人： Cedars-Sinai Medical Center

发明人： MURALI, Ramachandran ,  KANZAKI, Hirotaka

IPC分类号： C07C315/00 ,  C07C317/00 ,  C07C317/14

CPC分类号： A61K31/4174 ,  A61K31/04 ,  A61K31/10 ,  A61K31/403 ,  A61K31/4164 ,  A61K31/428 ,  A61K31/445 ,  A61K31/495 ,  A61K31/5375

摘要： The invention provides methods and agents that modulate RelA activity. These methods and modulators of RelA activity can be used to treat cancer progression of basal-like breast cancer, such as triple-negative breast cancer.

公开(公告)号：EP2046388B1

公开(公告)日：2017-12-13

申请号：EP07836531.9

申请日：2007-08-03

申请人： Wyeth LLC

发明人： SHAH, Syed, M. ,  OFSLAGER, Christian ,  FAWZI, Mahdi, B. ,  BAZHINA, Natalyia

IPC分类号： A61K47/18 ,  A61K31/485

CPC分类号： A61K9/0019 ,  A61K31/485 ,  A61K47/02 ,  A61K47/183

公开(公告)号：EP2528921B1

公开(公告)日：2017-10-18

申请号：EP11702369.7

申请日：2011-01-27

申请人： Theron Pharmaceuticals, Inc.

发明人： PFISTER, Jurg, R. ,  RESCOURIO, Gwenaella ,  VENKATRAMAN, Meenakshi, S. ,  ZHANG, Xiaoming

IPC分类号： C07D487/08 ,  A61K31/407 ,  A61P11/00

CPC分类号： A61K31/407 ,  A61K9/0078 ,  A61K31/4188 ,  A61K45/06 ,  C07D487/08 ,  C07D487/20 ,  Y02A50/475

摘要： Muscarinic acetylcholine receptor antagonists and methods of using them for the treatment of muscarinic acetylcholine receptor-mediated diseases, such as pulmonary diseases, are provided.

公开(公告)号：EP2535956B1

公开(公告)日：2017-10-11

申请号：EP12168689.3

申请日：2012-05-21

申请人： Samsung Display Co., Ltd.

发明人： Shin, Hyea-Weon ,  Lee, Seung-Mook ,  Park, Sang-Hun ,  Kim, Jae-Bok ,  Kim, Young-II ,  Ha, Jae-Kook

IPC分类号： H01L51/00 ,  H01L51/56

CPC分类号： H01L51/0014 ,  H01L27/3246 ,  H01L51/0015 ,  H01L51/0016 ,  H01L51/0017 ,  H01L51/0018 ,  H01L51/0019 ,  H01L51/003 ,  H01L51/5056 ,  H01L51/56