公开(公告)号：EP2616044A1

公开(公告)日：2013-07-24

申请号：EP11724702.3

申请日：2011-05-23

申请人： Cilpa Limited

发明人： PURANDARE, Shrinivas, Madhukar ,  MALHORTA, Geena

IPC分类号： A61K9/00 ,  A61K9/12 ,  A61K31/415 ,  A61K47/24 ,  A61J1/00 ,  A61K9/28 ,  A61K47/48 ,  G01N1/00

CPC分类号： A61K31/437 ,  A61K9/146 ,  A61K9/16 ,  A61K9/2846 ,  A61K9/2866 ,  A61K9/2886 ,  G01N2013/006 ,  Y10T428/2982

摘要： A composition comprising rifaximin in the form of particles, wherein substantially all the particles have a particle size less than or equal to 2 micrometres.

摘要翻译： 包含颗粒形式的利福昔明的组合物，其中基本上所有的颗粒具有小于或等于2微米的粒度。

公开(公告)号：EP2611987A2

公开(公告)日：2013-07-10

申请号：EP11752605.3

申请日：2011-08-31

申请人： Halliburton Energy Services, Inc.

发明人： LEVIN, Stewart, A. ,  DUSTERHOFT, Ronald, G. ,  LONGBOTTOM, Jim. ,  WARPINSKI, Norman, R. ,  VICK, James, D. Jr.

IPC分类号： E21B33/12 ,  E21B49/00 ,  E21B47/01

CPC分类号： E21B47/01 ,  E21B33/1208 ,  E21B49/00

摘要： A system for monitoring a parameter of a subterranean formation using swellable materials is disclosed. The system may include a sensor device configured to detect a parameter of a subterranean formation. The system may also include a swellable material configured to position the sensor device toward a surface of the subterranean formation by swelling of the swellable material. The system may further include a telescoping section coupled to the sensor device and emplaced in the swellable material. The telescoping section may be configured to extend with the positioning of the sensor device.

公开(公告)号：EP2591064A1

公开(公告)日：2013-05-15

申请号：EP11738459.4

申请日：2011-07-07

申请人： Halliburton Energy Services, Inc.

发明人： SHIRSHOVA, Natasha ,  MENNER, Angelika ,  BISMARK, Alexander ,  FUNKHOUSER, Gary, P.

IPC分类号： C09K8/46 ,  C04B24/28 ,  C04B28/00

CPC分类号： C09K8/46 ,  C04B28/02 ,  C04B2103/0046 ,  C04B22/068 ,  C04B2103/12 ,  C04B2103/22 ,  C04B24/2641

摘要： A method for isolating a portion of a wellbore including preparing a sealant composition includes an emulsion of an internal phase and an external phase. The sealant composition is placed into the wellbore where one phase sets upon subjecting the sealant composition to a thermal source followed by the setting of the other phase.

公开(公告)号：EP2521833A2

公开(公告)日：2012-11-14

申请号：EP11700197.4

申请日：2011-01-06

申请人： Halliburton Energy Services, Inc.

发明人： MANKE, Kevin, Ray ,  MARTIN, Tracy, M. ,  CLAYTON, Robert, Preston

IPC分类号： E21B17/06

CPC分类号： E21B17/06 ,  E21B31/00 ,  E21B31/007 ,  E21B31/18

摘要： A downhole tool releasing mechanism which includes a collet for releasably engaging a mandrel of a downhole tool. A retaining band is circumferentially disposed about the fingers of the collet for maintaining engagement of the collet and the mandrel prior to application of a predetermined axially directed force on the releasing mechanism. Upon application of such a force the collet fingers expand, breaking the shear band, the mandrel is released and the downhole tool is disengaged.

公开(公告)号：EP2509453A2

公开(公告)日：2012-10-17

申请号：EP10836638.6

申请日：2010-12-08

申请人： TIN Inc. d/b/a Temple-Inland

发明人： HOPKINS, Anne Chace ,  LOWE, Matthew W.

IPC分类号： A23L1/29 ,  A23K1/16

CPC分类号： A23L1/3082 ,  A23K10/37 ,  A23L29/262 ,  A23L33/105 ,  A23L33/24 ,  A61K31/736 ,  C08B37/0087 ,  Y02P60/877

摘要： A Nutritional Composition comprising soluble extractable material from a lignocellulosic source. A method of producing a composition, comprising providing a lignocellulosic source, extracting soluble materials from the lignocellulosic source to produce soluble extractable material, and processing the soluble extractable material to yield a Nutritional Composition, wherein the Nutritional Composition comprises hemicellulose and exhibits pathogen blocking, anti-adhesion activity.

公开(公告)号：EP2324042A1

公开(公告)日：2011-05-25

申请号：EP09791228.1

申请日：2009-08-06

申请人： Sicor, Inc.

发明人： BIGATTI, Ettore ,  LUX, Giovanna ,  PAIOCCHI, Maurizio ,  GIOLITO, Andrea ,  TOSI, Simone

IPC分类号： C07H19/12 ,  C07H1/00 ,  A61K31/706

CPC分类号： C07H1/00 ,  C07H19/12 ,  Y10T436/147777

摘要： The present invention provides a processes for preparing 5 -Azacytidine, and intermediates thereof, said process Comprising reacting a silylated 5-azacytosine of the formula (II), a sugar moiety having of the formula (III): and a protic acid; wherein R is a substituted or non substituted C
1 -C
20 acyl moiety, R
1 , R
2 and R
3 are each independently H or an alkyl group, and X is a halogen. The present invention further provides an analytical method for determining the purity of 5-Azacytidine in a sample.

摘要翻译： 本发明提供了用于制备5-氮杂胞苷及其中间体的方法，所述方法包括使式（II）的甲硅烷基化5-氮杂胞嘧啶，具有式（III）的糖部分和质子酸反应; 其中R为取代或未取代的C 1 -C 20酰基部分，R 1，R 2和R 3各自独立地为H或烷基，并且X为卤素。 本发明进一步提供了确定样品中5-氮杂胞苷纯度的分析方法。

公开(公告)号：EP2311838A1

公开(公告)日：2011-04-20

申请号：EP10179160.6

申请日：2007-08-14

申请人： Sicor, Inc.

发明人： Busolli, Jonathan ,  Diulgheroff, Nicola ,  Nemethne, Racz, Csilla ,  Pirkes, Moran ,  Pontiroli, Alessandro ,  Villa, Macro ,  Aronhime, Judith

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： This invention relates a crystalline form of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and to a process for the preparation thereof.

摘要翻译： 本发明涉及N- [4- [2-（2-氨基-4,7-二氢-4-氧代-1H-吡咯并[2,3-d]嘧啶-5-基）乙基]苯甲酰基] -L-谷氨酸，培美曲塞二酸及其制备方法。

公开(公告)号：EP2270013A1

公开(公告)日：2011-01-05

申请号：EP10179141.6

申请日：2007-08-14

申请人： Sicor, Inc.

发明人： Busolli, Jonathan ,  Diulgheroff, Nicola ,  Nemethne, Racz, Csilla ,  Pirkes, Moran ,  Pontiroli, Alessandro ,  Villa, Macro ,  Aronhime, Judith

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： This invention relates a crystalline form of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and to a process for the preparation thereof.

公开(公告)号：EP2231612A1

公开(公告)日：2010-09-29

申请号：EP09702460.8

申请日：2009-01-19

申请人： Sicor, Inc.

发明人： GAVENDA, Ale ,  JEGOROV, Alexandr ,  ROSSETTO, Pierluigi ,  MACDONALD, Peter ,  CANAVESI, Augusto

IPC分类号： C07D213/81

CPC分类号： C07D213/81

摘要： Provided are sorafenib hemi-tosylate, polymorphs thereof, polymorphs of sorafenib tosylate, preparation thereof and pharmaceutical compositions thereof.

公开(公告)号：EP2139845A1

公开(公告)日：2010-01-06

申请号：EP08726184.8

申请日：2008-02-26

申请人： Teva Pharmaceutical Industries Ltd.

发明人： KANSAL, Vinod Kumar ,  MISTRY, Dhirenkumar N. ,  VASOYA, Sanjay L.

IPC分类号： C07C69/734 ,  C07C235/34 ,  C07C69/732 ,  C07C67/343 ,  C07C67/303 ,  C07C67/307 ,  C07C67/31 ,  C07D307/77

CPC分类号： C07C69/734 ,  C07C67/303 ,  C07C67/307 ,  C07C67/31 ,  C07C67/343 ,  C07C69/732 ,  C07C235/34 ,  C07C2602/08

摘要： Provided are intermediates Formulae (IV), (V), (VI), (VII), (IX) and processes for preparation of Ramelteon, wherein X = O-Alkyl or -NH2.

摘要翻译： 本发明提供中间体和方法用于制备雷美替胺的。