摘要:
The present invention relates to a chip equipped with a plurality of compact microfluidic valves with multiple inlets and outlets, actuated by means of a flexible membrane system. The chip preferably comprises a deformable sealing layer made of at least one flexible, elastic, and insulating material; a structure formed by a succession of one or several microstructured layers, wherein said structure comprises one or several micro-chambers, one or several microfluidic channels, and one or several fluidic inlets and outlets; and wherein said structure is installed on a base substrate. The invention likewise relates to a microfluidic device that comprises the aforementioned chip, to a method for the fabrication of the chip, and to the uses associated with the chip and the microfluidic device.
摘要:
The present invention describes a method for producing multifunctional materials comprising the steps of: a) chemically activating functional groups present in a micro- or nanoparticulate base material; b) performing a nucleophilic substitution reaction between at least one terminal amino, carboxyl or thiol group of a PNA or DNA type A chain and at least one activated functional group of the base material produced in step (a); c) conjugating to a biomolecule by means of chemically activating functional groups of a PNA/DNA type B chain, which is complementary to the PNA/DNA type A chain; and d) hybridizing the PNA/DNA type A chains which are bound to the base material according to step b) and the PNA/DNA type B chains having biomolecules bound thereto according to step c) by means of PNA-PNA or PNA-DNA molecular recognition.
摘要翻译:本发明描述了一种生产多功能材料的方法,包括以下步骤:a)化学活化存在于微粒或纳米颗粒基材中的官能团; b)在PNA或DNA A型链的至少一个末端氨基,羧基或硫醇基与步骤(a)中制备的至少一种活化的基础材料官能团之间进行亲核取代反应; c)通过化学活化与PNA / DNA A型链互补的PNA / DNA型B链的官能团与生物分子共轭; 和d)通过PNA-PNA或PNA-DNA将根据步骤b)与根据步骤b)结合的碱性物质的PNA / DNA A型链与根据步骤c)结合的生物分子的PNA / DNA B型链杂交 分子识别。
摘要:
The present invention relates to an in vitro method of diagnosis, prognosis and/or monitoring of pathologies caused by gliotoxin-producing fungi or their derivatives, characterized in that it is based on the detection of SS'-dimethyl-gliotoxin in a biological sample. Also relates to the use of the SS'-dimethyl-gliotoxin as marker for the diagnosis, prognosis and/or monitoring of pathologies caused by gliotoxin-producing fungi or their derivatives in a subject.
摘要:
The invention relates to an identification and verification system and to an associated method for the identification and verification of documents, based on the use of nanoparticles embedded or absorbed in the medium forming the document, whereby the different optical reflectance characteristics of the nanoparticles are used to provide highly effective forgery identification, by combining different nanoparticles each having unique properties.
摘要:
The invention relates to a fluidised-bed reactor (10, 20, 30, 40) comprising two zones (11,12, 21, 22; 31, 32; 41, 42), in which the upper zone (11, 21, 31, 41) has a different cross-section to the lower zone (12, 22, 32, 42). A zone with a reducing atmosphere is obtained in one of the two zones (11,12, 21, 22; 31, 32; 41, 42) and a zone with an oxidising atmosphere is obtained in the other zone. In a preferred embodiment of the invention, the cross-section of the upper zone (11, 21, 31, 41) is greater than that of the lower zone (12, 22, 32, 42), thereby producing a reducing atmosphere in the upper zone (11, 21, 31, 41) and an oxidising atmosphere in the lower zone (12, 22, 32, 42). In addition, rows of flow-distributing pipes are provided in the upper zone (11, 21, 31, 41) in order to prevent the appearance of dead zones.
摘要:
Magnetic hyperthermia application device (1) to apply magnetic hyperthermia treatment to a sample, characterized as such because it includes: an LC resonant tank (3), consisting of a first coil (5) and a first condenser (6), connected to an alternating voltage power supply (2) of variable frequency and a control medium (4) connected to the LC resonant tank (3) and to the alternating voltage power supply (2), which controls the voltage that the alternating voltage power supply (2) applies to the LC resonant tank (3), so that its frequency remains between 99% and 101% of the resonating frequency for this LC tank (3).
摘要:
Use of the general formula compound (I), or any salt thereof, for preparation of a pharmaceutical compound for the treatment of infectious illnesses, in particular for the treatment of helicobacter. Y equals NO 2 , COOH or SO 3 H; Z equals O, N or S; X 1 and X 2 are halogens which may be equal or different; and m and y take values from 0 to 3 and may be equal or different.
摘要翻译:通式化合物(I)或其任何盐用于制备用于治疗感染性疾病的药物化合物,特别是用于治疗螺杆菌的用途。 Y等于NO 2,COOH或SO 3 H; Z等于O,N或S; X 1和X 2是可以相同或不同的卤素; 并且m和y取0至3之间的值,并且可以相等或不同。
摘要:
The system is based on the arrangement of a plurality of terminals (1), (1')...(1 n ), which are interconnected with one another to form a digital network by means of two databuses, one write and one read, by means of differential transmission, with a hybrid connection topology based inter alia on UTP-type cables (4). Each terminal is constituted by a DLP-type card (7), which contains a programmable logic device for the management of a series of cards associated with the card (7), said cards being a main card (8) and a user-interface card (9), which enable the user to configure the various system options, it being possible, also, to incorporate one or more extension cards (H-H') for the input and output of audio/video signals, the Internet, a telephone line or an automatic-door-entry line, and also a remote-control and alarm card (10) for activating external loads, activating alarms and receiving signals originating from sensors.