公开(公告)号：EP2438608A2

公开(公告)日：2012-04-11

申请号：EP10784163.7

申请日：2010-06-04

申请人： Northwestern University

发明人： MIRKIN, Chad, A. ,  SHIM, Wooyoung ,  BRAUNSCHWEIG, Adam, B. ,  LIAO, Xing ,  CHAI, Jinan ,  LIM, Jong, Kuk ,  ZHENG, Gengfeng ,  ZHENG, Zijian

IPC分类号： H01L21/027

CPC分类号： G03F7/0002 ,  B81B2203/0361 ,  B81B2207/056 ,  B81C1/00111 ,  B81C1/0046 ,  B81C2201/0154 ,  B81C2201/0185 ,  B82Y10/00 ,  B82Y40/00 ,  Y10S977/732

摘要： Disclosed are methods of lithography using a tip array having a plurality of pens attached to a backing layer, where the tips can comprise a metal, metalloid, and/or semi-conducting material, and the backing layer can comprise an elastomeric polymer. The tip array can be used to perform a lithography process in which the tips are coated with an ink (e.g., a patterning composition) that is deposited onto a substrate upon contact of the tip with the substrate surface. The tips can be easily leveled onto a substrate and the leveling can be monitored optically by a change in light reflection of the backing layer and/or near the vicinity of the tips upon contact of the tip to the substrate surface.

公开(公告)号：EP2420520A1

公开(公告)日：2012-02-22

申请号：EP11178666.1

申请日：2007-05-14

申请人： Northwestern University

发明人： Chiesl, Thomas ,  Barron, Annelise E.

IPC分类号： C08F20/56

CPC分类号： C08F20/56 ,  C08F220/56 ,  C08F220/58

摘要： Linear acrylamide copolymer compounds which can comprise monomeric components comprising at least one N-substituted moiety capable of physical cross-linking, and related compositions and methods of use.

摘要翻译： 线性丙烯酰胺共聚物的化合物，其可以包括单体组分，其包含能够物理交联中的至少一个N- substituiertem部分，以及相关组合物和使用方法。

公开(公告)号：EP2365803A1

公开(公告)日：2011-09-21

申请号：EP09760436.7

申请日：2009-11-24

申请人： Northwestern University

发明人： MIRKIN, Chad, A. ,  GILJOHANN, David, A. ,  SEFEROS, Dwight ,  PRIGODICH, Andrew, E. ,  PATEL, Pinal, C.

IPC分类号： A61K9/51 ,  A61K47/48

CPC分类号： A61K31/713 ,  A61K9/51 ,  A61K47/6923 ,  A61K48/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2310/351 ,  C12N2310/531 ,  C12N2320/32

摘要： The present invention concerns nanoparticles functionalized with duplex RNA for a variety of uses, including but not limited to gene regulation. More specifically, the disclosure provides a new strategy for conjugating RNA to a nanoparticle to achieve increased stability and activity.

摘要翻译： 本发明涉及用于多种用途（包括但不限于基因调控）的双链RNA功能化的纳米颗粒。 更具体地，本公开提供了将RNA与纳米颗粒缀合以实现增加的稳定性和活性的新策略。

公开(公告)号：EP1157407B1

公开(公告)日：2010-11-17

申请号：EP00911560.1

申请日：2000-01-07

申请人： Northwestern University

发明人： MIRKIN, Chad, A. ,  PINER, Richard ,  HONG, Seunghum

IPC分类号： H01J49/00 ,  G03F7/00 ,  B82B3/00 ,  G01B7/34

CPC分类号： B82B3/00 ,  B05D1/007 ,  B05D1/185 ,  B05D1/26 ,  G01Q80/00 ,  G03F7/0002 ,  G03F7/165 ,  Y10S977/84 ,  Y10S977/857 ,  Y10S977/863 ,  Y10S977/877 ,  Y10T428/24917 ,  Y10T436/24

摘要： An atomic force microscope (AFM) having a tip coated with hydrophobic compounds, which is performed as dip pen nanolithography (DPN), for transporting molecules from the atomic force microscope tip (AFM) to a gold substrate (AU) to write patterns on the gold substrate (AU).

公开(公告)号：EP2195851A1

公开(公告)日：2010-06-16

申请号：EP08731989.3

申请日：2008-03-12

申请人： Northwestern University

发明人： MARKS, Tobin, J. ,  HAINS, Alexander, W.

IPC分类号： H01L31/00

CPC分类号： H01L51/0059 ,  B82Y10/00 ,  C08G2261/11 ,  C08G2261/124 ,  C08G2261/3142 ,  C08G2261/3162 ,  C08G2261/3422 ,  C08G2261/91 ,  H01L51/0038 ,  H01L51/0039 ,  H01L51/0043 ,  H01L51/0047 ,  H01L51/0094 ,  H01L51/4253 ,  H01L51/441 ,  H01L2251/308 ,  Y02E10/549

摘要： The present invention, in one aspect, relates to a solar cell. In one embodiment, the solar cell includes an anode; an active organic layer comprising an electron-donating organic material and an electron-accepting organic material; and an interfacial layer formed between the anode and active organic layer, where the interfacial layer comprises a hole-transporting polymer characterized with a hole- mobility higher than that of the electron-donating organic material in the active organic layer, and a small molecule that has a high hole-mobility and is capable of crosslinking on contact with air.

摘要翻译： 一方面，本发明涉及太阳能电池。 在一个实施例中，太阳能电池包括阳极; 包含给电子有机材料和受电子有机材料的活性有机层; 以及在阳极和活性有机层之间形成的界面层，其中界面层包含空穴迁移率高于活性有机层中电子给体有机材料的空穴迁移率的空穴迁移聚合物和小分子， 具有高空穴迁移率并且能够在与空气接触时发生交联。

公开(公告)号：EP2185975A1

公开(公告)日：2010-05-19

申请号：EP08795169.5

申请日：2008-08-08

申请人： Northwestern University

发明人： MIRKIN, Chad, A. ,  WANG, Yuhang ,  GIAM, Louise, R. ,  PARK, Matthew

IPC分类号： G03F7/00

CPC分类号： G03F7/0002 ,  B01L3/0255 ,  B01L2200/12 ,  B01L2400/0484 ,  B41M5/00 ,  G01Q80/00

摘要： An improved method of loading tips and other surfaces with patterning compositions or inks for use in deposition. A method of patterning is described, the method comprising: (i) providing at least one array of tips; (ii) providing a plurality of patterning compositions; (iii) ink jet printing at least some of the patterning compositions onto some of the tips; and (iv) depositing at least some of the patterning compositions onto a substrate surface; wherein the ink jet printing is adapted to prevent substantial cross-contamination of the patterning composition on the tips. Good printing reproducibility and control of printing rate can be achieved. The surfaces subjected to ink jet printing can be treated to encourage localization of the ink at the tip. The method is particularly important for high density arrays.

公开(公告)号：EP2183325A1

公开(公告)日：2010-05-12

申请号：EP08795560.5

申请日：2008-08-25

申请人： Northwestern University

发明人： GREEN, Alexander, A. ,  HERSAM, Mark, C.

IPC分类号： C09D5/24 ,  C09D7/12 ,  H01B1/24

CPC分类号： C09D5/24 ,  B82Y10/00 ,  B82Y20/00 ,  B82Y30/00 ,  C08K3/041 ,  C09D7/70 ,  H01B1/24 ,  Y10T428/265

摘要： Various methods related to the preparation of transparent electrical conductors based on carbon nanotubes having enhanced optical and electrical properties are disclosed. In some embodiments, the methods involve employing carbon nanotubes that have been presorted according to electronic type and/or optical absorbance for use in transparent electrical conductors. Other embodiments involve use of carbon nanotube bundles that have been pre-sorted according to bundle density.

公开(公告)号：EP2160464A2

公开(公告)日：2010-03-10

申请号：EP08756546.1

申请日：2008-05-30

申请人： Northwestern University

发明人： MIRKIN, Chad, A. ,  GILJOHANN, David, A. ,  SEFEROS, Dwight ,  PATEL, Pinal, C.

IPC分类号： C12N15/11

CPC分类号： C12N15/113 ,  A61K9/51 ,  A61K31/7088 ,  C12N15/111 ,  C12N15/87 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/351 ,  C12N2320/32

摘要： Materials and methods for modulating cellular uptake of functionalized nanoparticles are provided. Also provided are materials and methods for modulating the effectiveness of a therapeutic agent with a functionalized nanoparticle.

摘要翻译： 提供调节功能化纳米颗粒细胞摄取的材料和方法。 还提供了用于调节具有官能化纳米颗粒的治疗剂的有效性的材料和方法。

公开(公告)号：EP2121987A2

公开(公告)日：2009-11-25

申请号：EP08729548.1

申请日：2008-02-11

申请人： Northwestern University

发明人： MIRKIN, Chad, A. ,  SEFEROS, Dwight ,  GILJOHANN, David, A.

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6876 ,  C12Q1/6816 ,  C12Q2563/155

摘要： Methods describing the use of nanoparticles modified with binding moieties are provided.

摘要翻译： 提供了描述使用结合部分修饰的纳米粒子的方法。

公开(公告)号：EP2015751A2

公开(公告)日：2009-01-21

申请号：EP07776443.9

申请日：2007-04-27

申请人： Northwestern University

发明人： WATTERSON, Martin ,  VAN ELDIK, Linda ,  HU, Wenhui

IPC分类号： A61K31/506 ,  C07D403/12 ,  A61P25/00 ,  A61P25/28

CPC分类号： A61K31/506 ,  C07D403/12

摘要： The invention relates to stable and substantially purified synthetic pharmaceutically acceptable acid addition salts of pyridazine compounds of the formula I wherein R10 is hydrogen, hydroxyl, alkyl, alkoxy, alkenyl, alkynyl, alkylene, aryl, heteroaryl, sulfonyl, sulfinyl, sulfenyl, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, cyano, halo, =0, =S, carboxyl, carbonyl, carbamoyl, carboxamide, or phosphonate, and R11 is alkyl, alkoxy, alkenyl, alkynyl, alkylene, alkenylene, alkenyloxy, aryl, aryloxy, arylalkoxy, aroyl, heteroaryl, heterocyclic, acyl, acyloxy, sulfonyl, sulfinyl, sulfenyl, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, cyano, halo, =0, =S, phosphonate, carboxyl, carbonyl, carbamoyl, carboxamide, or ureido. The invention also relates to formulations, dosage forms and compositions comprising the salts, and methods of using the salts, formulations, dosage forms and compositions.