公开(公告)号：EP2766092A1

公开(公告)日：2014-08-20

申请号：EP12780868.1

申请日：2012-10-12

申请人： Technische Universiteit Delft

发明人： BEEKMAN, Frederik Johannes ,  BOM, Victor Robert

IPC分类号： A61N5/10 ,  G01T1/29

CPC分类号： A61N5/1067 ,  A61N5/1043 ,  A61N5/1048 ,  A61N5/1071 ,  A61N5/1075 ,  A61N5/1084 ,  A61N2005/1052 ,  A61N2005/1076 ,  A61N2005/1087 ,  G01T1/2935

摘要： A hadron radiation installation adapted to subject a target to irradiation by a hadron radiation beam includes a target support configured to support, preferably immobilize, a target; a hadron radiation apparatus adapted to emit a hadron radiation beam along a beam axis to irradiate the target supported by the target support, the radiation beam penetrating into the target. The radiation apparatus has a control system at least comprising a beam penetration depth control allowing at least to control and vary the penetration depth of the radiation beam into the target. The installation has a radiation beam range sensor device adapted to determine the penetration depth of said radiation beam into the target, where the range sensor device includes a gamma camera responsive to prompt gamma rays that are emitted while the hadron radiation beam penetrates into the target.

摘要翻译： 适于使目标受到强子辐射束照射的强子辐射装置包括构造成支撑，优选地固定靶的目标支撑件; 强子辐射装置，其适于沿着光束轴线发射强子辐射束，以照射由目标支撑体支撑的靶，所述辐射束穿透到所述靶中。 辐射装置具有至少包括光束穿透深度控制的控制系统，其允许至少控制和改变辐射束到目标中的穿透深度。 该装置具有辐射束范围传感器装置，其适于确定所述辐射束进入目标物的穿透深度，其中范围传感器装置包括响应于在强子辐射束穿透到靶中时发射的迅速伽马射线的伽马照相机。

公开(公告)号：EP1992965A3

公开(公告)日：2014-03-19

申请号：EP08103379.7

申请日：2008-04-04

申请人： Siemens Aktiengesellschaft

发明人： Rietzel, Eike

IPC分类号： G01T1/169 ,  A61N5/10 ,  G01T1/29

CPC分类号： G01T1/169 ,  A61B6/583 ,  A61N2005/1052 ,  A61N2005/1076 ,  G01T1/29 ,  G01T1/2985

摘要： Die Erfindung betrifft ein Verfahren zur Kalibrierung eines Positronen-Emissions-Tomographen einer Strahlentherapievorrichtung, indem zumindest eine definierte Strahlendosis in einem Probenkörper appliziert wird, indem die durch die Strahlendosis erzeugte Aktivität mit dem Positronen-Emissions-Tomographen gemessen wird, und indem der Positronen-Emissions-Tomograph mithilfe der gemessenen Aktivität kalibriert wird. Weiterhin betrifft die Erfindung eine zur Durchführung des Verfahrens ausgebildete Strahlentherapievorrichtung mit einem Positronen-Emissions-Tomographen.

公开(公告)号：EP2701604A1

公开(公告)日：2014-03-05

申请号：EP12721356.9

申请日：2012-04-25

申请人： Koninklijke Philips N.V. ,  Philips Intellectual Property & Standards GmbH

发明人： SOLF, Torsten ,  RIBBING, Carolina ,  VAN LOON, Petrus Wilhelmus Helena

IPC分类号： A61B6/00 ,  A61N5/10 ,  G01T1/164 ,  G01T1/24

CPC分类号： A61B6/4258 ,  A61B6/037 ,  A61N5/1001 ,  A61N2005/1052 ,  A61N2005/1061 ,  G01V5/0041

摘要： The invention relates to an energy application apparatus for applying energy to an object, wherein the object (2) comprises a location (3) with radioactive material and wherein the energy application apparatus (1) comprises a location detection unit being usable for detecting the location with the radioactive material, and an x-ray unit for applying x-rays to the detected location of the object. Since the location, to which energy should be applied, comprises radioactive material, this location can be accurately detected by using the location detection unit. Moreover, since the application of the x-rays can be well controlled by controlling, for example, the intensity and the energy spectrum of the x-rays, energy can be accurately applied to the accurately detected location. The overall process of applying energy to the object can therefore be performed with increased accuracy.

公开(公告)号：EP2651513A1

公开(公告)日：2013-10-23

申请号：EP11811381.0

申请日：2011-12-13

申请人： Koninklijke Philips N.V.

发明人： OJHA, Navdeep ,  MORICH, Michael Andrew

IPC分类号： A61N5/10 ,  G01N33/48 ,  A61B5/055

CPC分类号： A61N5/1039 ,  A61B5/0035 ,  A61B5/055 ,  A61B5/0555 ,  A61B6/032 ,  A61B6/037 ,  A61B6/4417 ,  A61B6/5247 ,  A61N5/1071 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1061 ,  G01R33/4808 ,  G01R33/481 ,  G01R33/4812

摘要： A radiation therapy planning and follow-up system(10) includes an MR scanner (12) with a first bore (16) which defines an MR imaging region (18)and a functional scanner (26), e.g.,a nuclear imaging scanner,or a CT scanner with a second bore (30) which defines a nuclear or CT imaging region (36). The first and second bores (16,30) have a diameter of at least 70cm, and preferably 80-85 cm. A radiation therapy type couch (90) moves linearly through the MR imaging region (18) along an MR longitudinal axis and the nuclear or CT imaging region (36) along a nuclear or CT longitudinal axis which is aligned with the MR longitudinal axis. The couch positions a subject sequentially in the MR and nuclear or CT imaging regions (18, 36). A fusion processor combines an image representation generated from data collection in the MR imaging region (18) and an image representation generated from data collection in the nuclear or CT imaging region (36) into a composite image representation and a planning processor (112) generates a radiation therapy treatment plan according to the composite image.

公开(公告)号：EP2543413A1

公开(公告)日：2013-01-09

申请号：EP11750710.3

申请日：2011-03-02

申请人： Inter-University Research Institute Corporation High Energy Accelerator Research Organization

发明人： NAGAMINE, Kanetada

IPC分类号： A61N5/10

CPC分类号： A61N5/10 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087 ,  G01N23/00 ,  G01T1/29

摘要： By obtaining µSR signals of positive muons produced by particle radiation themselves stopped at a Bragg peak position of the charged particle radiation pulses such as proton beams, radiological effects in particle radiation therapy such as proton beams therapy are precisely known. When 230 MeV protons emitted from an accelerator are taken in, proton beam pulses are emitted from a irradiation apparatus 11, and at each time when a patient (human body 2) to accept therapy is irradiated, only the delay positrons produced due to decay of forward muons produced by the same protons at the Bragg peak position in the living body are selected in position and in time by using lead shielding plates 4 and delay signals, where information of positron produced positions and the times of delay simultaneous signals is measured by each positron counter of the first position sensitive positron counter board 9 and each positron counter of the second position sensitive positron counter board 10. Thus, delay positrons are measured, and then the measured results are analyzed to display µSR signals segmented for each positron produced position in the vicinity of the Bragg peak position of the protons on a display apparatus 8.

摘要翻译： 通过获得由粒子辐射产生的正μ子的μSR信号本身停止在诸如质子束的带电粒子辐射脉冲的布拉格峰值位置处，粒子辐射治疗（诸如质子束治疗）中的放射学效应是精确已知的。 当从加速器发射的230MeV质子被吸入时，从照射装置11发射质子束脉冲，并且在每次当接受治疗的患者（人体2）被照射时，仅仅由于衰减而产生的延迟正电子 通过使用铅屏蔽板4和延迟信号在位置和时间上选择由活体中布拉格峰值位置处的相同质子产生的前向μ子，其中正电子产生位置的信息和延迟同时信号的时间由每个测量 第一位置敏感正电子计数器板9的正电子计数器和第二位置敏感正电子计数器板10的每个正电子计数器。因此，测量延迟正电子，然后分析测量结果以显示按照每个正电子产生位置分割的μSR信号 显示装置8上的质子的布拉格峰值位置附近。

公开(公告)号：EP2412405A1

公开(公告)日：2012-02-01

申请号：EP10756051.8

申请日：2010-03-23

申请人： National University Corporation Hokkaido University

发明人： ISHIKAWA, Masayori

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61B6/52 ,  A61N5/1037 ,  A61N5/1039 ,  A61N5/1065 ,  A61N5/1067 ,  A61N2005/0626 ,  A61N2005/1052 ,  G06T7/70

摘要： An organism (12) is irradiated with therapeutic radiation from a radiation irradiation device (40). A pair of two-dimensional radiation detectors (30-1, 30-2) are arranged so as to face one another with the irradiated therapeutic radiation passing therebetween, and detect the two-dimensional positions irradiated by a pair of annihilation γ rays produced when a positron emitted from a positron-emitting radionuclide is annihilated. On the basis of a pair of positions detected by the pair of two-dimensional radiation detectors (30-1, 30-2), a radionuclide position detecting unit (32) detects the position of the positron-emitting radionuclide, and the radiation irradiation device (40) irradiates the position of the positron-emitting radionuclide with therapeutic radiation.

摘要翻译： 用辐射照射装置（40）的治疗辐射照射有机体（12）。 一对二维辐射检测器（30-1,30-2）被布置为以照射的治疗辐射通过它们彼此面对，并且检测由一对湮灭³射线照射的二维位置 从正电子发射放射性核素发射的正电子被消灭。 基于由一对二维辐射检测器（30-1,30-2）检测的一对位置，放射性核素位置检测单元（32）检测正电子发射放射性核素的位置，并且辐射照射 装置（40）用治疗辐射照射正电子发射放射性核素的位置。

公开(公告)号：EP2127697A4

公开(公告)日：2010-07-28

申请号：EP08711733

申请日：2008-02-21

申请人： UNIV HOKKAIDO NAT UNIV CORP ,  INST NAT COLLEGES TECH JAPAN

发明人： KANEKO JUNICHI ,  SHIRATO HIROKI ,  FUJITA FUMIYUKI ,  TAKADA EIJI

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61B2090/392 ,  A61N5/1064 ,  A61N2005/1052

公开(公告)号：EP2078537A1

公开(公告)日：2009-07-15

申请号：EP09000253.6

申请日：2009-01-09

申请人： Kabushiki Kaisha Toshiba ,  Toshiba Medical Systems Corporation

发明人： Sakurai, Yasuo ,  Takada, Yoichi ,  Kumakura, Masahiro ,  Ohyu, Shigeharu ,  Haragashira, Motoji ,  Nambu, Kyojiro ,  Shibata, Mariko

IPC分类号： A61N5/10

CPC分类号： A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1054

摘要： A radiotherapy treatment support apparatus (1) includes a storage unit (7) which stores absorption dose volume data expressing a spatial distribution of absorption dose in a subject, a generation unit (5) which generates fusion data associated with morphology volume data of the subject and the absorption dose volume data so as to be associated with a plurality of segments, and a display unit (6) which displays an image which has the distribution of absorption dose superimposed on the two-dimensional morphology image of the subject using the fusion data.

摘要翻译： 一种放射治疗处理支援装置（1）具备存储单元（7），该存储单元（7）存储表示受试者的吸收剂量的空间分布的吸收剂量体积数据，生成单元（5），生成单元（5）生成与对象的形态体数据相关联的融合数据 和吸收剂量体数据以与多个区段相关联;以及显示单元（6），其使用融合数据显示具有叠加在对象的二维形态学图像上的吸收剂量分布的图像 。

公开(公告)号：EP1898796A2

公开(公告)日：2008-03-19

申请号：EP06774408.6

申请日：2006-06-29

申请人： Accuray Incorporated

发明人： FU, Dongshan ,  KUDUVALLI, Gopinath ,  ALLISON, John

IPC分类号： A61B8/08

CPC分类号： A61N5/1049 ,  A61B8/08 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1058 ,  A61N2005/1061 ,  A61N2005/1062

摘要： An apparatus and method of dynamically tracking a soft tissue target with ultrasound images, without the use of fiducial markers.

公开(公告)号：EP1642545A1

公开(公告)日：2006-04-05

申请号：EP05027381.2

申请日：1998-12-01

申请人： Sherwood Services AG

发明人： Cosman, Eric, R.

IPC分类号： A61B19/00 ,  A61B6/08 ,  A61N5/10

CPC分类号： A61B6/5247 ,  A61B5/1127 ,  A61B6/0421 ,  A61B6/0492 ,  A61B6/08 ,  A61B34/20 ,  A61B90/10 ,  A61B90/14 ,  A61B90/16 ,  A61B90/20 ,  A61B2034/102 ,  A61B2034/2055 ,  A61B2034/2065 ,  A61B2034/2068 ,  A61B2034/2072 ,  A61B2090/363 ,  A61B2090/364 ,  A61B2090/371 ,  A61B2090/378 ,  A61B2090/3937 ,  A61B2090/395 ,  A61B2090/3966 ,  A61B2090/3983 ,  A61B2090/502 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/107 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1052 ,  A61N2005/1059 ,  A61N2005/1061 ,  G06T7/73 ,  G06T2207/10081 ,  G06T2207/30204

摘要： A system for positioning and repositioning of a portion of a patient's body with respect to a treatment or imaging machine includes multiple cameras to view the body and the machine. Index markers, either light-emitting, passive, geometric shapes, or natural landmarks, are identified and located by the cameras in 3D space. In one embodiment, such reference or index markers are in a determinable relationship to analogous markers used during previous image scanning of the patient. Anatomical targets determined from image scanning can be located relative to reference positions associated with the treatment or diagnostic machine. Several forms of camera, index markers, methods and systems accommodate different clinical uses. X-ray imaging of the patient further refines anatomical target positioning relative to the treatment or diagnostic imaging reference point. Movements of the patient based on comparative analysis of imaging determined anatomical targets relative to reference points on treatment or diagnostic apparatus are controlled by the system and process of the invention.

摘要翻译： 用于相对于治疗或成像机器定位和重新定位患者身体的一部分的系统包括用于观察身体和机器的多个照相机。 索引标记，无论是发光，被动，几何形状，还是自然地标，都由相机在3D空间中识别和定位。 在一个实施例中，这种参考或索引标记与在患者的先前图像扫描期间使用的类似标记是可确定的关系。 从图像扫描确定的解剖目标可以相对于与治疗或诊断机器相关联的参考位置定位。 摄像机，指标标记，方法和系统的几种形式适应不同的临床应用。 患者的X射线成像进一步优化了相对于治疗或诊断成像参考点的解剖学目标定位。 通过本发明的系统和方法控制基于成像的比较分析确定的解剖靶标相对于治疗或诊断装置上的参考点的运动。