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    Dioxolobenzisoxazole derivatives and process for preparing the same
    54.
    发明公开
    Dioxolobenzisoxazole derivatives and process for preparing the same 失效
    二氧代苯并噻唑衍生物及其制备方法

    公开(公告)号：EP0197533A3

    公开(公告)日：1988-01-13

    申请号：EP86104714

    申请日：1986-04-07

    申请人： Chugai Seiyaku Kabushiki Kaisha

    发明人： Koga, Hiroshi ,  Dan, Takashi ,  Sato, Haruhiko ,  Onuma, Eturo

    IPC分类号： C07D498/04 ,  A61K31/42 ,  C07D317/00 ,  C07D261/00

    CPC分类号： C07D498/04

    摘要： Dioxolobenzisoxazole derivatives of the formula
    wherein R 1 is a phenyl group which may be substituted with a halogen atom, a lower alkyl group having 1-3 carbon atoms or a lower haloalkyl group, or a thienyl group; R 2 is a hydrogen atom or a lower alkyl group having 1-4 carbon atoms; and X and Y which may be the same or different represent a hydrogen atom or a halogen atom, as well as non-toxic salts thereof wherein R 2 is a hydrogen atom, a process for preparing the same and a pharmaceutical composition containing the same are disclosed. The derivatives have diuretic and uricosuric activities and, therefore, are useful as a drug for treating hyperuricemia or hypertension.