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公开(公告)号：EP3886820B8
公开(公告)日：2023-05-17
申请号：EP19889873.6
申请日：2019-11-27
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公开(公告)号：EP4166158A1
公开(公告)日：2023-04-19
申请号：EP21821552.3
申请日：2021-06-10
发明人： KAWAOKA, Yoshihiro , IMAI, Masaki , YAMAYOSHI, Seiya , ISHII, Ken , KOBIYAMA, Kouji , NAMBA, Eiko , OKA, Tatsuya , TOZUKA, Miyuki , JONAI, Nao , ONODERA, Yoshikuni , TAKESHITA, Fumihiko , SUZUKI, Takashi , NIWA, Takako , KOIZUMI, Makoto , NAKAMURA, Kensuke
IPC分类号： A61K39/00 , A61K39/215 , A61K48/00 , A61P31/12 , A61P31/14 , C07K14/165 , A61K9/107 , A61K9/14 , A61K47/14 , A61K47/18 , A61K47/24 , A61K47/28 , C12N15/50 , C12N15/88 , A61K31/7105
摘要： The present invention provides a vaccine for preventing and/or treating infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
The present invention relates to a lipid particle encapsulating a nucleic acid molecule capable of expressing the S protein and/or a fragment thereof of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), wherein the lipid comprises a cationic lipid represented by general formula (Ia) or a pharmaceutically acceptable salt thereof
wherein R 1 and R 2 each independently represent a C 1 -C 3 alkyl group;
L 1 represents a C 17 -C 19 alkenyl group which may have one or a plurality of C 2 -C 4 alkanoyloxy groups;
L 2 represents a C 10 -C 19 alkyl group which may have one or a plurality of C 2 -C 4 alkanoyloxy groups or a C 10 -C 19 alkenyl group which may have one or a plurality of C 2 -C 4 alkanoyloxy groups; and
p is 3 or 4.-
公开(公告)号：EP4157215A1
公开(公告)日：2023-04-05
申请号：EP21730469.0
申请日：2021-06-01
申请人： Athenion AG
发明人： SAAR, Ingo , BRYSCH, Wolfgang
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公开(公告)号：EP4129275A1
公开(公告)日：2023-02-08
申请号：EP21779530.1
申请日：2021-03-30
IPC分类号： A61K31/045 , A23L5/00 , A24B15/00 , A24D3/00 , A61K9/08 , A61K9/48 , A61K9/72 , A61K47/08 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/46 , A61P1/00 , A61Q13/00
摘要： An object of the present invention is to provide is a novel composition and others. The composition comprises l-menthol and at least one ingredient (X) selected from dicarboxylic acid esters, diol esters, monocarboxylic acid esters, esters of polyols having three or more hydroxy groups, esters of polycarboxylic acids having three or more carboxyl groups, polyol ethers, polyamines, and alcohols having six or more carbon atoms.
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公开(公告)号：EP4119130A1
公开(公告)日：2023-01-18
申请号：EP21769015.5
申请日：2021-03-09
发明人： YOSHIHARA Naoki , HASHIMOTO Shota , KIMATA Ryota
摘要： According to one embodiment of the present invention, granules having a high content of an active ingredient and a high uniformity of particle size are provided. Alternatively, according to one embodiment of the present invention, a preparation containing granules having a high content of an active ingredient and a high uniformity of particle size is provided. According to one embodiment of the present invention, a granule is provided that comprises a nuclear material, a melt component layer arranged on a surface of the nuclear material, and an active ingredient-containing layer arranged on a surface of the melt component layer, wherein the melt component layer contains a first melt component and the active ingredient-containing layer contains an active ingredient and a second melt component or a polymer having compatibility with the first melt component.
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公开(公告)号：EP4119129A1
公开(公告)日：2023-01-18
申请号：EP21766854.0
申请日：2021-03-09
发明人： YOSHIHARA Naoki , HASHIMOTO Shota , KIMATA Ryota
摘要： Provided is a melt granulated product with a high particle size homogeneity. Alternatively, provided is a pharmaceutical composition using said melt granulated product. Alternatively, provided is a melt granulated product with a high drug content. Alternatively, provided is a pharmaceutical composition using the melt granulated product. According to one embodiment of the present invention, a granule is provided that comprises an active ingredient, a melt component, and a polymer, wherein the active ingredient, the melt component and the polymer are bound. In addition, the melt component may be solid at room temperature, and have a melting point of 100°C or less. The polymer may be solid at room temperature, and have a glass transition point of 100°C or less.
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公开(公告)号：EP4110398A1
公开(公告)日：2023-01-04
申请号：EP21760482.6
申请日：2021-02-25
发明人： LI, Jack Chongyang , JIA, Haiqun , ZOU, Hui , WANG, Minghan
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公开(公告)号：EP4104828A1
公开(公告)日：2022-12-21
申请号：EP21754361.0
申请日：2021-02-09
发明人： OKAWA Koji , OTAKA Kuniaki , SATO Hiroyuki , INAKURA Hiroshi , KURIKI Masaaki
IPC分类号： A61K31/196 , A61K9/70 , A61K47/06 , A61K47/12 , A61K47/14 , A61K47/20 , A61K47/32 , A61K47/34 , A61P29/00
摘要： Disclosed is a patch for alleviating cancerous pain. The patch is provided with a support layer and an adhesive layer laminated on the support layer. The adhesive layer contains an adhesive base and 150-225 mg of diclofenac sodium. One patch is used by being attached once per day.
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公开(公告)号：EP3870227B1
公开(公告)日：2022-12-21
申请号：EP19828892.0
申请日：2019-10-23
发明人： KLUFT, Bastiaan , HODGINS, Niall
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