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197 条记录 (耗时 0.019 秒)

    MICRO PARTICLES FOR ORAL DELIVERY IN ANIMALS
    62.
    发明公开
    MICRO PARTICLES FOR ORAL DELIVERY IN ANIMALS 有权
    微粒口头对待动物

    公开(公告)号：EP2588089A1

    公开(公告)日：2013-05-08

    申请号：EP11766698.2

    申请日：2011-04-07

    申请人： Eurhema S.r.l. ,  Marcello, Arduini ,  Lauro, Arduini

    发明人： MARCELLO, Arduini ,  LAURO, Arduini

    IPC分类号： A61K9/26

    CPC分类号： A61K9/0068 ,  A61K9/5015 ,  A61K31/14 ,  A61K31/198 ,  A61K47/12

    摘要： A system for the controlled release of one or more physiologically or pharmacologically active substances, comprising compositions in the form of micro particles or granules, particularly for use in the zootechnical and/or veterinary field. The micro particles include a core which contains one or more substances having a pharmacological action, food supplements or diagnostic media, said one or more substances being characterized by the presence, within their chemical structure, of a basic functional group, specifically including an amine functional group. The core comprises also one or more carboxylic acids and/or their salts and eventually one or more excipients. Said core is coated by an outer layer of fats or waxes, and preferably by a mixture of glyceride of fatty acids.

    ALTERING ANIMAL WASTE COMPOSITION
    65.
    发明公开
    ALTERING ANIMAL WASTE COMPOSITION 有权
    CHANGE组成动物粪便

    公开(公告)号：EP1684794A1

    公开(公告)日：2006-08-02

    申请号：EP04793705.7

    申请日：2004-10-04

    申请人： Agresearch Limited

    发明人： LEDGARD, Stewart Francis

    IPC分类号： A61K38/43 ,  A23K1/165

    CPC分类号： A61K9/0068 ,  A01K5/00 ,  A61K9/0034

    摘要： A delivery device for altering the composition of animal waste, characterised in that the delivery device is adapted to deliver to an animal one or more treatment substances that can directly or indirectly affect the conversion of nitrogen containing compounds in animal waste, once the waste is excreted from the animal.

    DEVICE FOR ADMINISTRATION OF BENEFICIAL MATERIALS TO RUMINANTS
    66.
    发明授权
    DEVICE FOR ADMINISTRATION OF BENEFICIAL MATERIALS TO RUMINANTS 失效
    DEVICE FOR递送的材料，以反刍动物

    公开(公告)号：EP0739198B1

    公开(公告)日：2003-09-17

    申请号：EP95907154.9

    申请日：1995-01-20

    申请人： Agresearch Limited

    发明人： MUNDAY, Rex, New Zealand Pastoral Agriculture Res.

    IPC分类号： A61K9/22 ,  A61K9/00

    CPC分类号： A61K9/0068

    摘要： The invention described is a bolus for the controlled release of a beneficial agent in the rumen of a ruminant animal. The bolus consists in a core containing a binder, solubilising agent, the beneficial agent to be released and, when required, a densifier. The core is coated with a wax coating, preferably with an opening exposing a small part of the core to rumen juices. The core is gradually dissolved releasing the beneficial agent. As the core dissolves the wax coating erodes until the bolus disappears completely.

    RELEASE DEVICES
    68.
    发明公开
    RELEASE DEVICES 失效
    摄影装置

    公开(公告)号：EP0999824A1

    公开(公告)日：2000-05-17

    申请号：EP98925803.3

    申请日：1998-06-01

    申请人： CASTEX PRODUCTS LIMITED

    发明人： WHITEHEAD, Derek, James

    IPC分类号： A61K9/00 ,  C22C23/02

    CPC分类号： A61K9/0068 ,  C22C23/02

    摘要： An alloy for use in the manufacture of boli for adminstration to ruminant animals, the alloy including a major proportion of magnesium, aluminium in an amount of less than 8 % by weight and copper to enhance the rate of the galvanic corrosion of the alloy, the copper being present in an amount of more than 0.5 % by weight. Example boli include a bolus comprising a tubular sheath made from the alloy which surrounds a core component, the sheath and core being galvanically coupled. Boli including the alloy of the present invention provide relatively high magnesium release rates as well as providing an overall higher proportion of available magnesium for assimilation by the animal.

    Sustained release capsule and formulations for insertion into rumen
    69.
    发明公开
    Sustained release capsule and formulations for insertion into rumen 失效
    Pansen的Kapsel und Zusammensetzungen mitverzögerterWirkstoffabgabe zurEinführung

    公开(公告)号：EP0715847A2

    公开(公告)日：1996-06-12

    申请号：EP96200392.7

    申请日：1992-04-03

    申请人： ELI LILLY AND COMPANY

    发明人： Lowe, Lionel Barry ,  McArthur, Colin John

    IPC分类号： A61K9/00

    CPC分类号： A61K9/0068

    摘要： A sustained release capsule adapted to be inserted into the rumen of a ruminant animal and means for retention of the capsule in the rumen.
    A sustained release capsule ( 8 ) adapted to be inserted into the rumen of a ruminant animal through its oesophagus and retained within the rumen over a prolonged period to continuously deliver a biologically active composition ( 32 ) carried in the capsule ( 8 ), comprising an elongated tubular body ( 10 ) comprising a tube ( 16 ) and an end cap ( 12 ) secured to one end thereof for substantially enclosing the biologically active composition ( 32 ), the other end of the capsule ( 8 ) being a delivery end ( 18 ), the body ( 10 ) having an opening ( 20 ) at the delivery end ( 18 ) of the capsule ( 8 ) for delivery of the composition ( 32 ) to the rumen, and a plurality of retention arms ( 44 ) attached to or formed integrally with the cap ( 12 ), the arms ( 44 ) being adapted to extend outwardly from the cap ( 12 ) for retaining the capsule ( 8 ) in the rumen, the arms ( 44 ) being resilient to enable them to bend from their outwardly extending positions toward the body ( 10 ) so that they lie alongside the body ( 10 ) allowing the capsule ( 8 ) to be inserted through the animal's oesophagus, the resilient arms ( 44 ) normally extending from the body ( 10 ) at an angle between 75° and 90° with respect to the axis of the tubular body ( 10 ), and for each arm ( 44 ) said cap ( 12 ) has an external curved surface ( 26 ) disposed with respect to the arm ( 44 ) so that when the arm ( 44 ) is bent toward the body ( 10 ), the arm ( 44 ) contacts the curved surface ( 26 ) and the curved surface ( 26 ) controls the bending of the arm ( 44 ) so that the arm ( 44 ) does not bend abruptly, said arms ( 44 ) being adapted to return to their outwardly extending positions when the capsule ( 8 ) reaches the rumen, characterised in that said cap ( 12 ) is secured to said one end by means of at least two circumferential beads ( 30 ) having at least one sealing ring ( 31 ) located therebetween.

    摘要翻译： 适于插入反刍动物的瘤胃的持续释放胶囊和将胶囊保留在瘤胃中的装置。 一种缓释胶囊（8），其适于通过其食道插入反刍动物的瘤胃中并在长时间内保留在瘤胃内以连续输送携带在胶囊（8）中的生物活性组合物（32） ），包括细长的管状体（10），其包括管（16）和固定到其一端的端盖（12），用于基本上封闭所述生物活性组合物（32），所述胶囊（8）的另一端为 输送端（18），主体（10）在胶囊（8）的输送端（18）处具有用于将组合物（32）输送到瘤胃的开口（20）和多个保持臂（44） ），所述臂（44）适于从所述盖（12）向外延伸以将所述胶囊（8）保持在所述瘤胃内，所述臂（44）具有弹性，以使它们 从其向外延伸的位置朝向主体（10）弯曲，使得它们与主体（10）一起放置在允许位置 将胶囊（8）插入通过动物的食道，弹性臂（44）通常相对于管状体（10）的轴线以75度和90度之间的角度从主体（10）延伸， 并且对于每个臂（44），所述盖（12）具有相对于臂（44）设置的外部弯曲表面（26），使得当臂（44）朝向主体（10）弯曲时，臂（44） ）接触弯曲表面（26）并且弯曲表面（26）控制臂（44）的弯曲，使得臂（44）不突然弯曲，所述臂（44）适于返回到其向外延伸的位置 当所述胶囊（8）到达所述瘤胃时，其特征在于，所述帽（12）通过至少两个周向珠（30）固定到所述一端，所述周向珠具有位于其间的至少一个密封圈（31）。