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133 条记录 (耗时 0.021 秒)

    ANTITUMOR AGENT CONTAINING CARBON DIOXIDE AS ACTIVE INGREDIENT
    71.
    发明公开
    ANTITUMOR AGENT CONTAINING CARBON DIOXIDE AS ACTIVE INGREDIENT 审中-公开
    含有二氧化碳作为活性成分的抗癌剂

    公开(公告)号：EP2692348A1

    公开(公告)日：2014-02-05

    申请号：EP12765909.2

    申请日：2012-03-22

    申请人： Neochemir, Inc. ,  CO2BE Medical Engineering K.K. ,  National University Corporation Kobe University

    发明人： AKISUE, Toshihiro ,  MIWA, Masahiko ,  UEHA, Takeshi ,  TANAKA, Masaya

    IPC分类号： A61K33/00 ,  A61P35/00 ,  A61P35/02 ,  A61P43/00

    CPC分类号： A61K33/00 ,  A61K9/00

    摘要： An antitumor agent comprising carbon dioxide as an active ingredient of the present invention can reduce the tumor volume or eradicate the tumor of a patient who is difficult to take a surgical therapy, a chemotherapy, a radiation therapy or an immunotherapy. The antitumor agent comprising carbon dioxide as an active ingredient of the present invention is useful because the agent enables (1) the reduction in size or elimination of a tumor, (2) the suppression of tumor metastasis and also (3) the reduction in volume or elimination of a tumor at a part different from the part where carbon dioxide is transdermally absorbed by the transdermal absorption of carbon dioxide through the skin near the tumor or the skin far from the tumor. When the antitumor agent comprising carbon dioxide as an active ingredient of the present invention is used in combination with a surgical therapy, a chemotherapy, a radiation therapy or an immunotherapy, the effect can be potentiated or side effects can be reduced as compared with a monotherapy or a multidisciplinary therapy thereof

    摘要翻译： 包含二氧化碳作为本发明活性成分的抗肿瘤剂可减少肿瘤体积或根除难以进行手术治疗，化学疗法，放射疗法或免疫疗法的患者的肿瘤。 本发明的含有二氧化碳作为有效成分的抗肿瘤剂是有用的，因为该试剂能够（1）减小肿瘤尺寸或消除肿瘤，（2）抑制肿瘤转移并且还（3）体积减少 或在二氧化碳透皮吸收通过肿瘤附近的皮肤或远离肿瘤的皮肤透皮吸收二氧化碳透皮吸收部位的部位消除肿瘤。 当将包含二氧化碳作为本发明活性成分的抗肿瘤剂与手术疗法，化学疗法，放射疗法或免疫疗法结合使用时，与单一疗法相比，可以增强效果或减少副作用 或其多学科疗法

    TUMOR MARKER FOR RENAL CANCER AND METHOD FOR DETERMINATION OF OCCURRENCE OF RENAL CANCER
    73.
    发明公开
    TUMOR MARKER FOR RENAL CANCER AND METHOD FOR DETERMINATION OF OCCURRENCE OF RENAL CANCER 审中-公开
    TUMORMARKERFÜRNIERENKREBS UND VERFAHREN ZUR BESTIMMUNG DES AUFTRETENS VON NIERENKREBS

    公开(公告)号：EP2063271A1

    公开(公告)日：2009-05-27

    申请号：EP07807677.5

    申请日：2007-09-13

    申请人： Shimadzu Corporation ,  National University Corporation Kobe University

    发明人： MASUDA, Taro ,  NISHIMURA, Osamu ,  OKUMURA, Katsuhiko ,  OKAMURA, Noboru ,  WATANABE, Makoto

    IPC分类号： G01N33/574 ,  C12Q1/34 ,  C12Q1/37 ,  C12Q1/527

    CPC分类号： G01N33/57438

    摘要： The present invention provides a tumor marker more highly specific to renal cancer. The present invention provides a method for identifying the morbidity of rental cancer. A tumor marker for renal cancer comprising proteins identified from renal cancerous tissue. A method for identifying the morbidity of renal cancer by using the tumor marker for renal cancer. The method comprises measuring the level of the protein in a sample derived from a person of interest who is to be examined to identify the morbidity of renal cancer; and comparing an obtained measured level to a normal level of the protein, wherein an upregulation or a downregulation of the obtained measured level compared to the normal level is used as one of indexes indicating that there is a high possibility that the person of interest has renal cancer.

    摘要翻译： 本发明提供了对肾癌更高度特异性的肿瘤标志物。 本发明提供了一种鉴定出租癌症发病率的方法。 包括肾癌组织鉴定的蛋白质的肾癌肿瘤标志物。 一种通过使用肾癌肿瘤标志物鉴定肾癌发病率的方法。 该方法包括测量衍生自待检查者的样品中蛋白质的水平，以鉴定肾癌的发病率; 将获得的测量水平与蛋白质的正常水平进行比较，其中将所获得的测量水平与正常水平相比的上调或下调用作指标之一，表明感兴趣的人有肾脏的可能性很高 癌症。

    DESIGN ASSIST DEVICE, DESIGN ASSIST METHOD, AND DESIGN ASSIST PROGRAM
    80.
    发明公开
    DESIGN ASSIST DEVICE, DESIGN ASSIST METHOD, AND DESIGN ASSIST PROGRAM 审中-公开

    公开(公告)号：EP3731035A1

    公开(公告)日：2020-10-28

    申请号：EP18891591.2

    申请日：2018-12-17

    申请人： Miki Pulley Co., Ltd ,  National University Corporation Kobe University

    发明人： SATO Ryuta ,  NAGAO Atsushi ,  HASHIMOTO Takeshi ,  SASAKI Taichi

    IPC分类号： G05B11/36 ,  G05D3/12 ,  H02P29/00

    摘要： In the design of a mechanical component for a mechanical device driven by a feedback controlled electric motor, the user is enabled to easily know how the properties of mechanical component affect the generation of abnormal vibrations of the mechanical device. In a design assist apparatus (1), the processor (11) is configured to set a plurality of parameters of a mathematical model of an analysis target component selected from one or more mechanical components (24, 56, 58) forming the mechanical device, compute a pole of a transfer function of the mechanical device associated with one or more vibration modes of the mechanical device according to the parameters, and create a stability determination diagram including an isoline of a real part of the pole of the transfer function.