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公开(公告)号：EP4286004A1
公开(公告)日：2023-12-06
申请号：EP22382516.7
申请日：2022-05-30
发明人： Moreno Herrero, Jorge , Haas, Heinrich , Erbar, Stephanie , Garcia Fernandez, Jose Manuel , Benito Hernandez, Juan Manuel , Lopez Fernandez, Jose , Sánchez Mellado, Práxedes
摘要： The present disclosure provides compositions comprising an oligosaccharide composition of formula I, wherein said compositions are useful for delivery of certain agents, including, for example, nucleic acids.
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公开(公告)号：EP4286003A1
公开(公告)日：2023-12-06
申请号：EP22382514.2
申请日：2022-05-30
发明人： Moreno Herrero, Jorge , Haas, Heinrich , Erbar, Stephanie , Garcia Fernandez, Jose Manuel , Ortiz Mellet, Maria del Carmen , Benito Hernandez, Juan Manuel , Lopez Fernandez, Jose , Jimenez Blanco, Jose Luis
IPC分类号： A61P35/00 , C07H15/14 , C07H15/26 , C07H21/02 , C07H21/04 , C07H99/00 , C07H1/00 , A61K47/54
摘要： The present disclosure provides compositions comprising an oligosaccharide composition of formula I, wherein said compositions are useful for delivery of certain agents, including, for example, nucleic acids.
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公开(公告)号：EP4169580A1
公开(公告)日：2023-04-26
申请号：EP21382961.7
申请日：2021-10-22
发明人： Moreno Herrero, Jorge , Haas, Heinrich , Erbar, Stephanie , Garcia Fernandez, José Manuel , Benito Hernandez, Juan Manuel , Lopez Fernandez, José
摘要： The present disclosure provides compositions comprising an oligosaccharide composition of formula I, wherein said compositions are useful for delivery of certain agents, including, for example, nucleic acids.
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公开(公告)号：EP3712147B1
公开(公告)日：2023-01-25
申请号：EP19735712.2
申请日：2019-01-04
发明人： WU, Chengde , MAO, Qinghua , LI, Yi , YU, Tao , CHEN, Shuhui
IPC分类号： C07H15/14 , A61K31/351 , A61K31/381 , A61P3/10
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公开(公告)号：EP2877481B1
公开(公告)日：2019-11-27
申请号：EP13823249.1
申请日：2013-07-26
发明人： COMPTON, Benjamin Jason , HAYMAN, Colin Malcolm , HERMANS, Ian Francis , LARSEN, David Samuel , PAINTER, Gavin Frank , ANDERSON, Regan James
IPC分类号： C07H15/04 , C07H15/14 , C07D309/02 , A61K31/7028 , A61P3/10 , A61P11/06 , A61P31/04 , A61P35/00 , A61P37/02 , A61P37/08
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76.发明授权SOLID FORMS OF (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL AND METHODS OF THEIR USE 有权（2S，3R，4R，5S，6R）-2-（4-氯-3-（4-乙氧基苄基）苯基）-6-（甲硫基）四氢-2H-吡喃-3,4,5-三醇的固体形式 及其使用方法
公开(公告)号：EP2332947B1
公开(公告)日：2017-11-01
申请号：EP11155100.8
申请日：2009-07-15
CPC分类号： C07H15/14 , A61K31/7028 , A61K31/7034 , C07H7/04
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公开(公告)号：EP2697240B1
公开(公告)日：2015-09-16
申请号：EP12719082.5
申请日：2012-04-12
申请人： Novartis AG
IPC分类号： C07H13/04 , C07H15/04 , C07H15/12 , C07H15/14 , C07H19/044 , C07H15/203 , A61P3/00 , C07D407/10 , C07D413/10 , C07D417/10 , A61K31/7034 , C07H19/24 , A61K45/06 , A61K31/7042 , A61K31/7048 , A61K31/7056 , A61K31/706 , C07H17/00 , C07H19/04
CPC分类号： A61K31/7048 , A61K31/7034 , A61K31/7042 , A61K31/7056 , A61K31/706 , A61K45/06 , C07D407/10 , C07D413/10 , C07D417/10 , C07H13/04 , C07H15/04 , C07H15/12 , C07H15/14 , C07H15/203 , C07H17/00 , C07H19/04 , C07H19/044 , C07H19/24 , A61K2300/00
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公开(公告)号：EP2697240A1
公开(公告)日：2014-02-19
申请号：EP12719082.5
申请日：2012-04-12
申请人： Novartis AG
IPC分类号： C07H13/04 , C07H15/04 , C07H15/12 , C07H15/14 , C07H19/044 , C07H15/203 , A61P3/00 , C07D407/10 , C07D413/10 , C07D417/10 , A61K31/7034 , C07H19/24
CPC分类号： A61K31/7048 , A61K31/7034 , A61K31/7042 , A61K31/7056 , A61K31/706 , A61K45/06 , C07D407/10 , C07D413/10 , C07D417/10 , C07H13/04 , C07H15/04 , C07H15/12 , C07H15/14 , C07H15/203 , C07H17/00 , C07H19/04 , C07H19/044 , C07H19/24 , A61K2300/00
摘要： The present invention provides a compound of formula I; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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79.发明公开Solid forms of (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol and methods of their use 有权作者（2S，3R，4R，5S，6R）-2-（4-氯-3-（4-乙氧基苄基）苯基）-6-（甲基硫）四氢-2H-吡喃-3,4,5-三醇固体形式 AND METHOD FOR USE
公开(公告)号：EP2332947A1
公开(公告)日：2011-06-15
申请号：EP11155100.8
申请日：2009-07-15
CPC分类号： C07H15/14 , A61K31/7028 , A61K31/7034 , C07H7/04
摘要： Solid forms of anhydrous (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol are disclosed, in addition to methods of their use in the treatment of various diseases and disorders.
摘要翻译： 无水（2S，3R，4R，5S，6R）-2-（4-氯-3-（4-乙氧基苄基）苯基）-6-（甲基硫）四氢-2H-吡喃-3,4,5-的固体形式 三醇是游离缺失光盘，除了它们在多种疾病和病症的治疗中的使用方法。
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80.发明公开PROCESS FOR EXTRACTION OF GLUCOSINOLATE S FROM BROCCOLI SEEDS 审中-公开VERFAHREN ZUR EXTRAKTION VON GLUCOSINOLAT S AUS BROKKOLISAMEN
公开(公告)号：EP2315596A1
公开(公告)日：2011-05-04
申请号：EP09782076.5
申请日：2009-08-21
申请人： DSM IP Assets B.V.
发明人： SCHÜTZ, Jan , WEHRLI, Christof
CPC分类号： A61K36/31 , A61K31/728 , B01J39/05 , B01J41/07 , C07H1/08 , C07H13/00 , B01D15/362 , B01D15/363
摘要： A new process for extracting and purifying glucosinolates from plant material, preferably broccoli sprouts or seeds is described. An alcoholic extract is adsorbed onto a basic resin and eluted with ammonia. Optionally, the alcoholic extract is passed through an ion-exchange column containing acidic resin prior to the adsorption/elution step.
摘要翻译： 描述了从植物材料，优选西兰花芽或种子中提取和纯化芥子油苷的新方法。 将醇提取物吸附到碱性树脂上并用氨洗脱。 任选地，在吸附/洗脱步骤之前，将醇提取物通过含有酸性树脂的离子交换柱。
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