-
公开(公告)号：EP3566749A1
公开(公告)日：2019-11-13
申请号：EP18735824.7
申请日：2018-01-09
发明人： HE, Haiying , JIANG, Zhigan , SHI, Weihua , XIA, Jianhua , LI, Jian , CHEN, Shuhui
IPC分类号： A61P31/22 , A61K31/426 , C07D417/12 , C07D277/54
摘要： Disclosed in the present invention are a new thiazole compound, particularly a compound represented by formula (I), a pharmaceutical composition thereof and applications thereof in the preparation of drugs for the treatment of diseases related to herpes simplex viruses.
-
公开(公告)号：EP3489235A1
公开(公告)日：2019-05-29
申请号：EP17830501.7
申请日：2017-07-21
发明人： CHEN, Bin , YAO, Yuanshan , CHEN, Yuan , LI, Ao , XU, Ran , HUANG, Zhensheng , TIAN, Dongdong , LI, Hongwei , YANG, Chengshuai , LI, Jian , CHEN, Shuhui
IPC分类号： C07D471/04 , C07D487/04 , A61K31/4985 , A61K31/437 , A61K31/4709 , A61K31/444 , A61P43/00
摘要： Provided are a tricyclic compound as shown in formula (I) as a CRTH2 inhibitor, or a pharmaceutically acceptable salt, a tautomer, a stereoisomer or a solvate thereof, and the use thereof in treating diseases related to CRTH2 receptors.
-
公开(公告)号：EP3418282A1
公开(公告)日：2018-12-26
申请号：EP17752706.6
申请日：2017-02-20
发明人： LIU, Shilan , WANG, Dahai , LIANG, Guibai , HU, Guoping , LI, Jian , CHEN, Shuhui
IPC分类号： C07D487/14 , C07D495/14 , A61P37/06
CPC分类号： C07D487/14 , C07D495/14 , Y02A50/465
摘要： Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.
-
公开(公告)号：EP3333157A1
公开(公告)日：2018-06-13
申请号：EP16834592.4
申请日：2016-08-03
发明人： CHEN, Shuhui , CHEN, Zhengxia , DAI, Meibi , XIE, Cheng , LI, Peng , ZHANG, Yang , LIANG, Guibai , WANG, Qiang , LIAO, Jiangpeng , SUN, Fei , HU, Guoping , LI, Jian
IPC分类号： C07D235/02 , C07D401/02 , C07D401/14 , C07D403/02 , C07D403/14 , A61K31/395 , A61K31/416 , A61P35/00
CPC分类号： C07D401/14 , A61K31/395 , A61K31/416 , A61P35/00 , C07D235/02 , C07D401/02 , C07D401/12 , C07D403/02 , C07D403/14 , C07D405/14 , C07D413/14
摘要： FGFR and VEGFR inhibitors are provided, and compounds represented by formula (1) or formula (II) as FGFR and VEGFR inhibitors, pharmaceutically acceptable salts or tautomers thereof are specifically disclosed.
-
公开(公告)号：EP3266785A1
公开(公告)日：2018-01-10
申请号：EP15875212.1
申请日：2015-12-29
发明人： DING, Charles Z. , SUN, Fei , WU, Lifang , DU, Jinhua , KATSU, Yasuhiro , HU, Guoping , LI, Jian
IPC分类号： C07D487/04 , A61K31/519 , A61P31/00 , A61P37/00 , A61P35/00 , A61P11/00
CPC分类号： C07D487/04 , A61K31/519 , A61P11/06 , A61P35/00 , A61P37/08 , C07D519/00
摘要： Disclosed are a novel pyrrolopyrimidine ring compound as a TLR7 agonist or a pharmaceutically acceptable salt thereof, used for preventing or treating allergic rhinitis and asthma. In particular, disclosed is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof
摘要翻译： 公开了一种新的吡咯并嘧啶环化合物作为TLR7激动剂或其药学上可接受的盐，用于预防或治疗过敏性鼻炎和哮喘。 具体而言，公开了由式（I）表示的化合物或其药学上可接受的盐
-
86.发明公开HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF 审中-公开HYDROXYLPURINVERBINDUNGEN UND ANWENDUNGEN DAVON
公开(公告)号：EP3205652A4
公开(公告)日：2017-08-16
申请号：EP15848312
申请日：2015-09-22
发明人： WU LINGYUN , ZHANG PENG , ZHANG LI , LI JIAN , CHEN SHUHUI , LONG CHAOFENG , CHEN XIAOXIN , LIU ZHUOWEI
IPC分类号： C07D473/30 , A61K31/52 , A61P9/00 , A61P19/02 , A61P29/00
CPC分类号： A61K31/522 , A61K31/52 , C07D241/10 , C07D261/06 , C07D277/20 , C07D473/30
摘要： Hydroxyl purine compounds represented by formula ( I ), tautomers or pharmaceutically acceptable salts thereof, and applications thereof as PDE2 or TNF-± inhibitors.
摘要翻译： 由式（I）表示的羟基嘌呤化合物，其互变异构体或其药学上可接受的盐以及其作为PDE2或TNF-α抑制剂的应用。
-
公开(公告)号：EP3205652A1
公开(公告)日：2017-08-16
申请号：EP15848312.3
申请日：2015-09-22
发明人： WU, Lingyun , ZHANG, Peng , ZHANG, Li , LI, Jian , CHEN, Shuhui , LONG, Chaofeng , CHEN, Xiaoxin , LIU, Zhuowei
IPC分类号： C07D473/30 , A61K31/52 , A61P9/00 , A61P19/02 , A61P29/00
CPC分类号： A61K31/522 , A61K31/52 , C07D241/10 , C07D261/06 , C07D277/20 , C07D473/30
摘要： Hydroxyl purine compounds represented by formula ( I ), tautomers or pharmaceutically acceptable salts thereof, and applications thereof as PDE2 or TNF-α inhibitors.
摘要翻译： 由式（I）表示的羟基嘌呤化合物，其互变异构体或药学上可接受的盐，以及其作为PDE2或TNF-α抑制剂的应用。
-
公开(公告)号：EP4434536A1
公开(公告)日：2024-09-25
申请号：EP22894677.8
申请日：2022-11-08
发明人： PAN, Zhixiang , HE, Haiying , JIANG, Zhigan , CHEN, Shuhui
IPC分类号： A61K38/26 , C07K14/605 , A61P3/10
CPC分类号： C07K14/605 , A61P3/10 , A61K38/26
摘要： A series of stapled peptides and a use thereof, specifically relating to a polypeptide having a sequence as shown in a formulas (I-1)-(I-5) and (II-6), and a pharmaceutically acceptable salt thereof.
-
公开(公告)号：EP4400499A1
公开(公告)日：2024-07-17
申请号：EP22866638.4
申请日：2022-09-07
发明人： LEI, Maoyi , WANG, Shaohui , XU, Yu , LUO, Yunfu , CHEN, Shuhui
IPC分类号： C07D401/14 , C07D401/00 , C07D401/04 , C07D519/00 , A61K47/64 , A61K39/395 , A61P29/00
CPC分类号： A61K31/519 , A61K39/395 , A61K47/64 , A61P29/00 , A61P37/02 , C07D401/14 , C07D401/00 , C07D401/04 , C07D519/00
摘要： Disclosed in the present invention are a glutarimide compound, and the use thereof. Specifically disclosed are a compound as represented by formula (VII-0) and a pharmaceutically acceptable salt thereof.
-
90.发明授权
公开(公告)号：EP4046686B1
公开(公告)日：2023-11-01
申请号：EP20876972.9
申请日：2020-10-16
发明人： WU, Lingyun , XIAO, Zheming , JIANG, Chunyan , LI, Jian , CHEN, Shuhui
IPC分类号： A61P11/00 , C07D401/04 , A61K31/4439
-
-
-
-
-
-
-
-
-
搜索结果
108 条记录 (耗时 0.036 秒)
