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公开(公告)号:EP1223224A1
公开(公告)日:2002-07-17
申请号:EP00963012.0
申请日:2000-09-29
申请人: KIKKOMAN CORPORATION , Sakaue, Ryoichi, Kikkoman Corporation , Arai, Ayumi, Kikkoman Corporation , Kajiyama, Naoki, Kikkoman Corporation , Koyama, Yasuji, Kikkoman Corporation
发明人: SAKAUE, Ryoichi , ARAI, Ayumi , KAJIYAMA, Naoki , KOYAMA, Yasuji
CPC分类号: C12Q1/26 , C12Q1/37 , G01N30/02 , Y10S435/975
摘要: Based on a principle that is different to that of a conventional enzymatic method, the present invention provides a novel method for assaying a glycated protein by a simple procedure, within a short period of time, and with high accuracy, and a reagent kit for assaying used in the method. The method for assaying a glycated protein in a sample is realized by treating a glycated protein-containing sample with protease to liberate a glycated peptide, preferably an α-glycated peptide, particularly preferably an α-glycated dipeptide, from a glycated protein, allowing an oxidase to react with the liberated glycated peptide, and determining the produced hydrogen peroxide.
摘要翻译: 基于与常规酶法不同的原理,本发明提供了一种通过简单的方法在短时间内和高精度测定糖化蛋白质的新方法,以及用于测定的试剂盒 用于该方法。 用于测定样品中糖基化蛋白质的方法是通过用蛋白酶处理含糖基化蛋白质的样品来实现的,以从糖基化蛋白质释放糖基化肽,优选α-甘氨酸肽,特别优选α-甘氨酸二肽,允许 氧化酶与释放的糖化肽反应,并测定所产生的过氧化氢。
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公开(公告)号:EP2992765B1
公开(公告)日:2023-07-05
申请号:EP14779754.2
申请日:2014-04-02
发明人: KANEKO Daisuke , AOYAMA Kenji , WIM Engels , ARNO Wegkamp , FEDDE Kingma
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公开(公告)号:EP3447132B1
公开(公告)日:2022-05-18
申请号:EP17786054.1
申请日:2017-04-21
IPC分类号: C12N9/04 , C12M1/40 , C12N15/09 , C12Q1/00 , C12Q1/32 , G01N27/327 , G01N27/416 , G01N33/483 , G01N33/49 , G01N33/72 , C12N9/88 , C12N9/02
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公开(公告)号:EP3369815B1
公开(公告)日:2022-03-09
申请号:EP16860014.6
申请日:2016-10-31
发明人: MASAKARI Yosuke , HARA Seiichi
IPC分类号: C12N9/02
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公开(公告)号:EP3677681A1
公开(公告)日:2020-07-08
申请号:EP18850676.0
申请日:2018-08-31
申请人: Kikkoman Corporation
发明人: ICHIYANAGI Atsushi
IPC分类号: C12N15/53 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/04 , C12P21/02 , C12Q1/00 , C07K14/805
摘要: Provided is a glycated hemoglobin oxidase with small measurement error or without deviation of the measured value from the true value regarding a sample containing glycated abnormal hemoglobin. Provided are a glycated hemoglobin oxidase comprising an amino acid sequence in which the amino acid at the position corresponding to position 113, 109, 106, or 102 of the amino acid sequence of SEQ ID NO: 1 is substituted with an amino acid other than a positively-charged amino acid, such as glutamic acid, alanine, or aspartic acid as well as a method and a reagent kit for measurement of glycated hemoglobin using such glycated hemoglobin oxidase. The glycated hemoglobin is capable of reacting with various genotypes and enables highly accurate measurement of glycated hemoglobin in a sample containing glycated abnormal hemoglobin.
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公开(公告)号:EP3608240A1
公开(公告)日:2020-02-12
申请号:EP18780688.0
申请日:2018-04-02
摘要: To provide a container including an inner container that is deformed as content decreases, the container being a dispensing container reusable and excellent in an aroma retaining property. To implement such container, a dispensing container (10) includes a container body (13) including a flexible inner container configured to be filled with content and to deflate as the content decreases, and an outer container encompassing the inner container and having an intake hole through which external air is taken into a space between the inner container and the outer container, a discharge cap (15) including a top surface part having a discharge port through which the content is discharged, the discharge cap (15) being mounted on a mouth portion (13a) of the container body (13), and an external air introduction hole that provides communication between the outside and the intake hole. The inner container and the outer container are made of a polyethylene terephthalate resin.
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公开(公告)号:EP3424517A1
公开(公告)日:2019-01-09
申请号:EP17779152.2
申请日:2017-04-04
申请人: Kikkoman Corporation , National Center for Global Health and Medicine , National Institute of Advanced Industrial Science and Technology
发明人: YOSHIO Sachiyo , KANTO Tatsuya , KAWASHIMA Tadaomi , IKARI Naho , TSUJI Noriko
摘要: An object of the present invention is to provide a composition for promoting interferon λ production, which contains an active ingredient exhibiting an effect of promoting interferon λ production with respect to BDCA3 DC, and a production method therefor. The present invention relates to (1) a composition for promoting interferon λ production, which contains a bacterial cell, a bacterial component, or a culture of lactic acid bacteria capable of being cultured under stress conditions, as an active ingredient, and (2) a method for producing a composition for promoting interferon λ production, which includes culturing lactic acid bacteria capable of being cultured under stress conditions so as to obtain a bacterial cell, a bacterial component, or a culture of the lactic acid bacteria.
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公开(公告)号:EP3409129A1
公开(公告)日:2018-12-05
申请号:EP17770299.0
申请日:2017-03-22
发明人: SATOH, Chie , NISHIBORI, Yuki , SUGAWARA, Ryu
CPC分类号: A23C11/103 , A23C11/10 , A23L11/00 , A23L11/31 , A23L11/35 , A23L27/2054 , A23L27/84 , A23V2002/00 , A23V2200/15
摘要: The present invention relates to a soy milk containing methylpyrazine compounds consisting of 2-methylpyrazine, 2,5-dimethylpyrazine and 2,6-dimethylpyrazine at a quantity of 40 to 7000 µg per 1 L.
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公开(公告)号:EP2915430B1
公开(公告)日:2018-08-08
申请号:EP13851857.6
申请日:2013-10-29
申请人: Kikkoman Corporation
CPC分类号: A23L5/10 , A23L27/00 , A23L27/21 , A23L27/50 , A23V2002/00 , A23V2200/15 , A23V2300/10 , A23V2300/12
摘要: The present invention relates to a powdery seasoning produced by drying and powdering a seasoning liquid obtained by enzymatically decomposing a protein-containing raw material derived from at least one of wheat and a soybean in the presence of salt, which has an inorganic material concentration of 50000 ppm or less, and a method for producing the same.
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