METHOD FOR EVALUATING SIMILARITY OF AGGREGATED DATA, SIMILARITY EVALUATION PROGRAM, AND SIMILARITY EVALUATION DEVICE
    6.
    发明公开
    METHOD FOR EVALUATING SIMILARITY OF AGGREGATED DATA, SIMILARITY EVALUATION PROGRAM, AND SIMILARITY EVALUATION DEVICE 审中-公开
    VERFAHREN,程序在VORRICHTUNG ZUR BEURTEILUNG DERÄHNLICHKEITAGGREGIERTER DATEN

    公开(公告)号:EP2717048A1

    公开(公告)日:2014-04-09

    申请号:EP12792480.1

    申请日:2012-05-31

    申请人: TSUMURA & CO.

    IPC分类号: G01N30/86 G01N30/88

    摘要: The object is to contribute to improvement of accuracy and efficiency in evaluation. Provided is a similarity evaluating device for collective data to evaluate similarity between collective data sets in which a plurality of pieces of data are collected. The device includes a patterning part patterning each data of collective data with a selected scale, a matching number extraction part comparing each patterned data in a round-robin to find numbers of matches, and a matching degree determination part finding a degree of matching on the basis of the found numbers of matches with the use of Tanimoto coefficient, thereby evaluating similarity of the collective data simply and quickly.

    摘要翻译: 目的在于提高评估的准确性和效率。 提供了一种用于评估其中收集多条数据的集合数据集之间的相似性的集体数据的相似性评估装置。 该装置包括图案化部分,以所选择的比例图案化集合数据的每个数据;匹配数量提取部分,比较循环中的每个图案化数据以找到匹配数;以及匹配度确定部分, 使用Tanimoto系数找到匹配次数的基础,从而简单快速地评估集体数据的相似性。

    METHOD FOR ATTRIBUTING PEAKS, ATTRIBUTION PROGRAM, AND ATTRIBUTION DEVICE
    7.
    发明公开
    METHOD FOR ATTRIBUTING PEAKS, ATTRIBUTION PROGRAM, AND ATTRIBUTION DEVICE 审中-公开
    VERFAHREN ZURZENZUNG VON SPITZENWERTEN,ZUORDNUNGSPROGRAMM UND ZUORDNUNGSVORRICHTUNG

    公开(公告)号:EP2717046A1

    公开(公告)日:2014-04-09

    申请号:EP12791980.1

    申请日:2012-05-31

    申请人: TSUMURA & CO.

    IPC分类号: G01N30/86 G01N30/88

    摘要: A peak assigning apparatus 1 for assigning peaks of a FP configured by peaks and retention time points of the peaks detected from a chromatogram of a multicomponent material, capable of contributing to improvement of the accuracy and efficiency of evaluation of an evaluation target, includes a peak pattern preparing part 7 preparing a peak pattern for each peak of the target FP and a reference FP that comprises n+1 peaks including n peaks being present on at least one of sides located in front and in the rear of each peak in a time axis direction, and a peak assigning part 9 specifying the peaks corresponding to each other by comparison of the peak patterns.

    摘要翻译: 用于分配由多组分材料的色谱图检测的峰的峰值和保留时间点构成的峰的峰值分配装置1,其能够有助于提高评价对象的评价的准确性和效率,包括峰值 图形准备部分7准备目标FP的每个峰值的峰值图案,以及包括n + 1个峰值的参考FP,其包括在位于每个峰值的时间轴的前后的至少一个侧面上的n个峰值 方向,峰值分配部分9通过比较峰值图案来指定彼此相对应的峰值。

    DAIKENCHUTO BIOASSAY METHOD AND QUALITY MANAGEMENT METHOD USING SAME
    8.
    发明公开
    DAIKENCHUTO BIOASSAY METHOD AND QUALITY MANAGEMENT METHOD USING SAME 有权
    达芬奇 - 生物多样性保护协会

    公开(公告)号:EP2647722A1

    公开(公告)日:2013-10-09

    申请号:EP11844371.2

    申请日:2011-11-28

    申请人: TSUMURA & CO.

    IPC分类号: C12Q1/02 G01N33/50

    摘要: The invention intends to provide a bioassay method using a simple in-vitro test for Daikinchuto, and further to provide a more highly accurate method for quality control of Daikenchuto using the same. These methods are a bioassay method for the pharmacological activity of Daikenchuto, characterized in that a test sample containing Daikenchuto is added to cultured serotonin-producing cells, and the serotonin content in the culture supernatant is subsequently measured; and a quality control method for Daikenchuto preparations in which the pharmacological activity of a test preparation and a reference preparation for which the pharmacological effect as Daikenchuto has been clinically confirmed are evaluated under the same conditions, and the equivalence of the reference preparation and testing preparation is evaluated.

    摘要翻译: 本发明旨在提供一种使用大金钟托的简单体外试验的生物测定方法,并且进一步提供使用其的Daikenchuto的更高精度的质量控制方法。 这些方法是Daikenchuto的药理活性的生物测定方法,其特征在于,将含有Daikenchuto的试验样品加入培养的产生血清素的细胞中,随后测量培养上清液中的5-羟色胺含量; 以及在相同的条件下评价试验制剂和作为戴肯丘的药理作用已被临床证实的对照制剂的药理活性的对照试验品质控制方法,参考制剂和试验制剂的等效性 评估。

    Method for producing sanshool
    9.
    发明公开
    Method for producing sanshool 有权
    Verfahren zur Herstellung von Sanshool

    公开(公告)号:EP2644612A1

    公开(公告)日:2013-10-02

    申请号:EP13160811.9

    申请日:2013-03-25

    申请人: TSUMURA & CO.

    发明人: Aoki, Katsuyuki

    摘要: Provided are a method for producing a sanshool, which can produce a sanshool in a short process and with high stereoselectivity, as well as a novel diene iron complex compound that is a stable intermediate useful for the production method. The diene iron complex compound is represented by the following general formula (I):

    (in which A represents CO, P(R A ) 3 , CN, NO, SO(R A ) 3 , or N(R A ) 2 ; R A represents a straight chain or branched chain alkyl group having 1 to 4 carbon atoms or an aryl group having 6 to 12 carbon atoms; and one of R 1 and R 2 represents a hydrogen atom and the other one thereof represents a structure represented by the following formula (II)):

    (in which R represents a hydrogen atom, a hydroxyl group, or a methyl group

    摘要翻译: 本发明提供一种能够以短立体选择性制造桑拿学校的方法,以及可用于生产方法的稳定中间体的新型二烯铁络合物。 二烯铁络合物由以下通式(I)表示:(其中A表示CO,P(RA)3,CN,NO,SO(RA)3或N(RA)2); RA表示直链 具有1至4个碳原子的直链或支链烷基或具有6至12个碳原子的芳基; R 1和R 2之一表示氢原子,另一个表示由下式(II )):(其中R表示氢原子,羟基或甲基