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公开(公告)号：EP3917626B1
公开(公告)日：2023-05-31
申请号：EP20702636.0
申请日：2020-01-30
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公开(公告)号：EP4424378A2
公开(公告)日：2024-09-04
申请号：EP24184312.7
申请日：2018-07-30
IPC分类号： A61P35/00
CPC分类号： A61K51/0482 , A61K51/0402 , A61K51/0497 , A61K2121/0020130101 , A61K2123/0020130101 , A61P35/00
摘要： The present invention relates to a ligand-SIFA-chelator conjugate, comprising, within in a single molecule three separate moieties: (a) one or more ligands which are capable of binding to a disease-relevant target molecule, (b) a silicon-fluoride acceptor (SIFA) moiety which comprises a covalent bond between a silicon atom and a fluorine atom, and (c) one or more chelating groups, optionally containing a chelated nonradioactive or radioactive cation.
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公开(公告)号：EP3658194A1
公开(公告)日：2020-06-03
申请号：EP18743540.9
申请日：2018-07-30
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公开(公告)号：EP4249456B1
公开(公告)日：2024-09-04
申请号：EP23167668.5
申请日：2020-01-30
CPC分类号： A61P35/00 , C07B2200/0520130101 , C07B59/008 , A61K51/0497 , A61K51/0406
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公开(公告)号：EP3877750B1
公开(公告)日：2024-09-25
申请号：EP19790227.3
申请日：2019-10-25
CPC分类号： G01J3/2823 , G01N21/031 , G01N21/6456 , G01N21/7746 , G02B21/361 , G02B26/001
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公开(公告)号：EP4008359B1
公开(公告)日：2024-09-11
申请号：EP21218180.4
申请日：2018-12-11
IPC分类号： A61K51/04
CPC分类号： A61K51/0482 , A61P35/00
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公开(公告)号：EP4414707A1
公开(公告)日：2024-08-14
申请号：EP23156155.6
申请日：2023-02-10
发明人： VOGELE, Kilian , SIMMEL, Friedrich
IPC分类号： G01N33/553 , G01N33/569
CPC分类号： G01N33/56911 , G01N2800/4420130101 , G01N33/553 , G01N2333/0120130101
摘要： The invention relates to a method for determining binding of a tail fiber protein to a cell surface epitope of a bacterium using tail fiber protein-coated nanoparticles that undergo plasmonic coupling upon binding to the bacterial epitope. The invention further relates to the use of said nanoparticles for the method described above. Moreover, the invention relates to a method for determining promising bacteriophage candidates for antimicrobial treatment using said nanoparticles. The invention further relates to a kit for detecting plasmonic coupling.
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公开(公告)号：EP3937117B1
公开(公告)日：2024-05-22
申请号：EP21194998.7
申请日：2017-06-23
CPC分类号： H04L63/1475 , H03M13/1102 , H03M13/13 , H03M13/2957 , H03M13/353 , H03M13/3707
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公开(公告)号：EP3512869B1
公开(公告)日：2024-02-28
申请号：EP17768767.0
申请日：2017-09-15
发明人： BERENSMEIER, Sonja , BLANK-SHIM, Silvia , SCHWAMINGER, Sebastian , FRAGA GARCIA, Paula , WENZEL, Wolfgang , FINK, Karin , ANAND, Priya , BORKOWSKA-PANEK, Monika
IPC分类号： C07K14/00
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公开(公告)号：EP3362557B1
公开(公告)日：2023-10-25
申请号：EP16762773.6
申请日：2016-09-05
发明人： ZVERLOV, Vladimir , SCHWARZ, Wolfgang , PRECHTL, Roman , LEIS, Benedikt , HELD, Claudia , LIEBL, Wolfgang
IPC分类号： C12N9/42
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