摘要:
The therapeutic use of bacteria, specifically but not only lactobacilli, which produce indole-3-aldehyde, or directly of indole-3-aldehyde itself, is proposed as a means of prevention and treatment of immune dysreactive disorders in which the hyper-inflammatory or autoimmune component represents the basic element
摘要:
The present invention relates to a process for the ultrapurification of alginates, in particular to be used for microencapsulation in human cell transplants.
摘要:
Method for the production of hydrogen from a fuel mixture substantially consisting of methane (CH 4 ) and carbon dioxide (CO 2 ) by means of a hydrogen production plant provided with carbonation reactor and calcination reactor, said method comprising the steps of: a) feeding said carbonation reactor with said fuel mixture; b) feeding said carbonation reactor with water vapor (gaseous H 2 O); c) feeding said carbonation reactor with calcium monoxide (CaO), said calcium monoxide (CaO) at least partially originating from said calcination reactor; d) production of hydrogen (H 2 ) and calcium carbonate (CaCO 3 ) from said carbonation reactor; e) feeding said calcination reactor, suitably heated, with said calcium carbonate (CaCO 3 ); f) production of calcium monoxide (CaO) and carbon dioxide (CO 2 ) from said calcination reactor, said calcium monoxide (CaO) and said carbon dioxide (CO 2 ) evolving by said calcium carbonate (CaCO 3 );
characterized in that during said controlled step of feeding said carbonation reactor with calcium monoxide (CaO), the ratio of the calcium monoxide (CaO) moles introduced in the carbonation reactor during step c) to the sum of the methane (CH 4 ) and carbon dioxide (CO 2 ) moles contained in said fuel mixture during the above-mentioned step a) is greater than 1.
摘要:
The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.
摘要:
The surgical instrument (1) for colon-rectum operations comprises: - a handle (2), - a shaft assembly (G) that frontally protrudes from the handle, - a first head (3) that frontally protrudes from the shaft assembly (G) comprising a mechanical stapler of 'cut-and-sew' type and adapted to cut and suture the colon-rectum; - a second head (4) that frontally protrudes from the shaft assembly (G) disposed at the side of the first head (3), comprising forceps adapted to tighten and strangulate the colon-rectum without cutting it; wherein the shaft assembly (G) and the first and the second heads (3, 4) are dimensioned in such manner to be inserted into a cannula of a trocar for laparoscopy, and where the forceps of the second head (4) comprise a plurality of nozzles (U, U') connected to at least a duct (47, 47') formed in the second head (4) and communicating with a main duct (75) formed in the shaft assembly (G) connected to a supply unit (B) adapted to supply a washing liquid that comes out of the nozzles (U, U') to wash the colon-rectum stump from top to bottom, said nozzles (U, U') being configured so as to pierce the wall of the colon-rectum, but not cross the colon-rectum from side to side.
摘要:
The surgical instrument (1) for colon-rectum operations comprises: - a handle (2), - a shaft assembly (G) that frontally protrudes from the handle, - a first head (3) that frontally protrudes from the shaft assembly (G) comprising a mechanical stapler of 'cut-and-sew' type and adapted to cut and suture the colon-rectum; - a second head (4) that frontally protrudes from the shaft assembly (G) disposed at the side of the first head (3), comprising forceps adapted to tighten and strangulate the colon-rectum without cutting it; wherein the shaft assembly (G) and the first and the second heads (3, 4) are dimensioned in such manner to be inserted into a cannula of a trocar for laparoscopy, and where the forceps of the second head (4) comprise a plurality of nozzles (U, U') connected to at least a duct (47, 47') formed in the second head (4) and communicating with a main duct (75) formed in the shaft assembly (G) connected to a supply unit (B) adapted to supply a washing liquid that comes out of the nozzles (U, U') to wash the colon-rectum stump from top to bottom, said nozzles (U, U') being configured so as to pierce the wall of the colon-rectum, but not cross the colon-rectum from side to side.
摘要:
The present invention concerns peptides able to impair the inhibiting activity of MDM2/MDM4 heterodimer towards p53 and maintain the association between MDM4 and p53 so to restore the p53 oncosuppressive function in cancer cells harboring wild type p53 protein, directing its function specifically towards an apoptotic outcome.
摘要:
The present invention concerns peptides able to impair the inhibiting activity of MDM2/MDM4 heterodimer towards p53 and maintain the association between MDM4 and p53 so to restore the p53 oncosuppressive function in cancer cells harboring wild type p53 protein, directing its function specifically towards an apoptotic outcome.