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    A MEASUREMENT DEVICE
    3.
    发明授权
    A MEASUREMENT DEVICE 有权
    测量装置

    公开(公告)号：EP2710352B1

    公开(公告)日：2017-09-27

    申请号：EP12720539.1

    申请日：2012-04-02

    申请人： WALLAC OY

    发明人： LAITALA, Ville

    IPC分类号： G01N21/64

    CPC分类号： G01N21/75 ,  G01D18/00 ,  G01N21/6452

    摘要： A measurement device includes mechanical support elements (101-104) for supporting a sample well, other mechanical support elements (105-109) for supporting a measurement head (112) suitable for optical measurements, and a control system (111) configured to control the measurement head to carry out at least two optical measurements from at least two different measurement locations inside the sample well, where each measurement location is a center point of a capture range from which radiation is captured in the respective optical measurement. The final measurement result is formed from the results of the at least two optical measurements in accordance with a pre-determined rule. The use of the at least two optical measurements from different measurement locations reduces measurement variation in situations where the sample well (153) contains a piece (158) of sample carrier.

    摘要翻译： 测量装置包括用于支撑样品井的机械支撑元件（101-104），用于支撑适于光学测量的测量头（112）的其他机械支撑元件（105-109），以及控制系统（111） 测量头从样本井内的至少两个不同的测量位置执行至少两个光学测量，其中每个测量位置是在相应的光学测量中捕获辐射的捕获范围的中心点。 根据预定规则，从至少两个光学测量的结果形成最终测量结果。 使用来自不同测量位置的至少两个光学测量结果减少了样品阱（153）包含样品载体件（158）的情况下的测量变化。

    METHODS FOR DETERMINING THE RISK OF PRENATAL COMPLICATIONS
    5.
    发明公开
    METHODS FOR DETERMINING THE RISK OF PRENATAL COMPLICATIONS 审中-公开
    VERFAHREN ZUR BESTIMMUNG DES RISIKOSPRÄNATALERKOMPLIKATIONEN

    公开(公告)号：EP3109322A1

    公开(公告)日：2016-12-28

    申请号：EP16173417.3

    申请日：2009-01-26

    申请人： Wallac Oy ,  The Fetal Medicine Foundation

    发明人： Cuckle, Howard ,  Nicolaides, Kypros ,  Ahola, Tarja

    IPC分类号： C12Q1/16

    CPC分类号： G01N33/689 ,  A61B5/021 ,  G01N33/6893 ,  G01N2333/471 ,  G01N2333/515 ,  G01N2800/368 ,  G01N2800/50 ,  G06F19/00 ,  G06Q50/24 ,  G16H50/30

    摘要： The disclosure relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual has for developing pre-eclampsia based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers. The disclosure also relates to methods, medical profiles, kits and apparatus for use in determining the risk that a pregnant individual is carrying a fetus having a chromosomal abnormality based on amounts of certain biochemical markers in a biological sample from the individual and biophysical markers.

    摘要翻译： 本公开涉及用于确定怀孕个体基于来自个体和生物物理标记的生物样品中某些生物化学标记物的量来发展先兆子痫的风险的方法，医学概况，试剂盒和装置。 本公开还涉及用于确定怀孕个体携带具有染色体异常的胎儿的风险的方法，医学概况，试剂盒和装置，其基于来自个体和生物物理标记的生物样品中某些生化标志物的量。

    SYSTEM AND METHOD FOR DETERMINING RISK OF DIABETES BASED ON BIOCHEMICAL MARKER ANALYSIS
    8.
    发明公开
    SYSTEM AND METHOD FOR DETERMINING RISK OF DIABETES BASED ON BIOCHEMICAL MARKER ANALYSIS 有权
    系统在VERFAHREN ZUR BESTIMMUNG DES DIABETESRISIKOS AUF基础DER分析生物化学品商标

    公开(公告)号：EP2972385A2

    公开(公告)日：2016-01-20

    申请号：EP14715412.4

    申请日：2014-02-26

    申请人： WALLAC OY

    发明人： HURSKAINEN, Pertti ,  KORPIMÄKI, Teemu ,  KOURU, Heikki ,  SAIRANEN, Mikko

    IPC分类号： G01N33/68

    CPC分类号： G01N33/689 ,  G01N2333/8132 ,  G01N2800/042 ,  G01N2800/368 ,  G01N2800/54

    摘要： A method for predicting risk of gestational diabetes mellitus (GDM) in a pregnant individual includes measuring one or more biochemical markers in a blood sample obtained from the pregnant individual to determine one or more biomarker levels, where the one or more measured biochemical markers includes at least one of PAI-2 and sTNFR1, identifying, for each of the one or more measured biochemical markers, a difference between the measured biomarker level and a corresponding predetermined control level, and, responsive to the identifying, determining a prediction corresponding to a relative risk of the pregnant individual having or developing GDM.

    摘要翻译： 用于预测怀孕个体的妊娠糖尿病（GDM）的风险的方法包括测量从怀孕个体获得的血液样品中的一种或多种生物化学标记物，以确定一种或多种生物标志物水平，其中所述一种或多种测量的生物化学标记物包括在 PAI-2和sTNFR1中的至少一个，针对所述一个或多个测量的生物化学标记中的每一个标识所测量的生物标志物水平与相应的预定控制水平之间的差异，并且响应于所述鉴定，确定对应于相对 怀孕个体患有或发展GDM的风险。