New process of making biomaterials
    3.
    发明公开
    New process of making biomaterials 审中-公开
    Neues Verfahren zur Herstellung von Biomaterialien

    公开(公告)号:EP1914209A1

    公开(公告)日:2008-04-23

    申请号:EP06122489.5

    申请日:2006-10-18

    IPC分类号: C03C1/00 C03C4/00 C01B33/16

    摘要: An improved sol-gel process is disclosed for the making of large synthetic silica based bioactive materials objects crack-free. A series of ordered mesoporous SiO 2 -CaO-P 2 O 5 sol-gel glasses which are highly bioactive has been synthesized through a sol-gel process. The mesoporous glasses are highly bioactive compared with conventional ones, due to the increased textural characteristics i.e. surface area. The bioactivity tests point out that the surface area, porosity, and 3D-structure become more important than chemical composition during the apatite crystallization stage in these materials, due to the very high textural parameters obtained. The product is intended to be used for tissue engineering applications.

    摘要翻译: 公开了一种改进的溶胶 - 凝胶方法,用于制造大的合成二氧化硅基生物活性材料物体无裂纹。 已经通过溶胶 - 凝胶法合成了一系列有序介孔SiO 2 -CaO-P 2 O 5溶胶凝胶玻璃,其具有高度的生物活性。 由于增加的结构特征,即表面积,介孔玻璃与常规玻璃相比具有高生物活性。 生物活性测试指出,由于获得的非常高的结构参数,表面积,孔隙率和3D结构在这些材料中的磷灰石结晶阶段期间比化学成分更重要。 该产品旨在用于组织工程应用。

    Process for the production of monoliths by means of the sol-gel process
    9.
    发明公开
    Process for the production of monoliths by means of the sol-gel process 有权
    Verfahren zur Herstellung von Monolithen durch ein Sol-Gel Verfahren

    公开(公告)号:EP1700831A1

    公开(公告)日:2006-09-13

    申请号:EP05005096.2

    申请日:2005-03-09

    摘要: Process for the production of monoliths by means of the sol-gel process, comprising the following steps:

    a. hydrolysis of an alkoxide in aqueous solution to form a hydrolysate and optionally evaporation to optimum concentration of the same,
    b. addition of an oxide prepared by the pyrogenic route,
    c. mixing of the hydrolysate of the alkoxide with the oxide prepared by the pyrogenic route to form a colloidal sol,
    d. optional removal of coarse contents from the colloidal sol,
    e. gelling of the colloidal sol in a mould,
    f. optional replacement of the water contained in the resulting aerogel by an organic solvent,
    g. drying of the aerogel,
    h. heat treatment of the dried aerogel, the coarse content being removed from the colloidal sol.

    摘要翻译: 通过溶胶 - 凝胶法生产整料的方法,包括以下步骤:a。 在水溶液中水解醇盐以形成水解产物,并任选地蒸发至最佳浓度,b。 加入通过热解法制备的氧化物,c。 将醇盐的水解产物与通过热解法制备的氧化物混合以形成胶体溶胶,d。 可选地从胶体溶胶中除去粗含量, 胶体胶体在模具中凝胶化,f。 用有机溶剂任选地替代所得气凝胶中所含的水,g。 干燥气凝胶,h。 干燥的气凝胶的热处理,从胶体溶胶中除去粗含量。