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公开(公告)号：EP2389162A1
公开(公告)日：2011-11-30
申请号：EP10701607.3
申请日：2010-01-26
发明人： SAMBURSKI, Guy , KURGAN, Ziv , MASARWA, Abed , SADYKHOV, Akper
IPC分类号： A61K9/16
CPC分类号： A61K9/5078 , A61K9/167 , A61K9/5089 , A61K31/41
摘要： Processes for coating a carrier with microparticles of a drug are described. For example, a coated carrier can be obtained in a one-stage process that entails evaporating a solvent from microdroplets of a solution containing an API to obtain dry microparticles, which are then coated on the carrier.
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公开(公告)号：EP2189457A1
公开(公告)日：2010-05-26
申请号：EP09180682.8
申请日：2004-01-16
IPC分类号： C07D403/10 , C07D235/02
CPC分类号： C07D235/02 , C07D403/10
摘要： The present invention provides a process for preparing irbesartan.
摘要翻译： 本发明提供了制备厄贝沙坦的方法。
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3.发明授权Aqueous dispersions and solutions of difficult to dissolve compounds and methods of their preparation 有权水分散体和微溶的物质和它们的制备方法的解决方案
公开(公告)号：EP1795183B1
公开(公告)日：2009-07-15
申请号：EP06252582.9
申请日：2006-05-12
发明人： Bershteyn, Yosef , Faingersh, Anna
CPC分类号： A61K9/08 , A61K9/0048 , A61K9/10 , A61K31/557 , A61K47/02 , A61K47/186
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公开(公告)号：EP2046470A2
公开(公告)日：2009-04-15
申请号：EP07866168.3
申请日：2007-07-10
申请人： Sicor, Inc.
IPC分类号： B01D29/01
CPC分类号： B01D29/01 , B01D29/54 , B01D29/965
摘要： An apparatus is provided for the separation of a resin from a reaction mixture. The apparatus comprises a column fitted with a side port, two inlet/outlet ports, and two flanges. Each flange is fitted with a multilayer net screen supported by a support grid. The column itself is attached to a support structure. A process is provided for using this apparatus to remove a resin from a reaction mixture, wherein the reaction mixture is added to the apparatus and the resin is filtered off, remaining in the column as the waste leaves. The remaining resin is then washed and eluted to provide a purified product.
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5.发明公开
公开(公告)号：EP2032586A2
公开(公告)日：2009-03-11
申请号：EP08743067.4
申请日：2008-04-18
发明人： KANSAL, Vinod, Kumar , CHAURASIA, Brijnath, P. , PATEL, Hitesh, K. , GOTHALIA, Vrajlal , GANDHI, Hiren
CPC分类号： C07F9/5352 , C07F7/1856 , C07F9/4006
摘要： The present invention relates to intermediates of rosuvastatin and processes for the production thereof.
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公开(公告)号：EP2007710A1
公开(公告)日：2008-12-31
申请号：EP08726267.1
申请日：2008-02-28
发明人： DEE-NOOR, Ziv , GOLD, Amir
IPC分类号： C07C227/16 , C07C229/28
CPC分类号： C07C227/16 , C07C229/28
摘要： This invention relates to an efficient process for converting gabapentin hydrochloride salt to gabapentin by liquid-liquid extraction using a counter-current extraction method.
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公开(公告)号：EP1992629A1
公开(公告)日：2008-11-19
申请号：EP08015768.8
申请日：2002-10-03
IPC分类号： C07D498/06 , C07D265/00 , C07D221/00
CPC分类号： C07D498/06
摘要： Levofloxacin was prepared by reacting (S)-(-)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid with N-methyl piperazine in a polar solvent or in a neat mixture to form levofloxacin. Further processing of the levofloxacin produced novel levofloxacin forms, including a hemihydrate and Forms A, B, C, F, G and H.
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公开(公告)号：EP1985287A2
公开(公告)日：2008-10-29
申请号：EP08251535.4
申请日：2008-04-25
发明人： Kanari, Itamar , Fox, Michael , Leibovici, Minutza
CPC分类号： A61K9/2018 , A61K9/1623 , A61K9/1641 , A61K9/1652 , A61K9/2027 , A61K9/2059
摘要： The present invention encompasses pharmaceutical excipient complexes comprising combining at least one carrier with an oily substance, and processes for preparing the same, stable pharmaceutical compositions comprising such complexes and active pharmaceutical ingredients and processes for preparing the same.
摘要翻译： 本发明包括药物赋形剂复合物，其包括将至少一种载体与油性物质组合，及其制备方法，包含该配合物的稳定药物组合物和活性药物成分及其制备方法。
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公开(公告)号：EP1934197A2
公开(公告)日：2008-06-25
申请号：EP07795403.0
申请日：2007-05-23
发明人： SANTIAGO, Ini , KOLTAI, Tamas , SHABAT, Shalom
IPC分类号： C07D333/20 , A61K31/381 , A61P25/24
CPC分类号： C07D333/20
摘要： A crystalline form of duloxetine hydrochloride, pharmaceutical compositions of the crystalline form of duloxetine hydrochloride, and methods of preparing the crystalline form of duloxetine hydrochloride are provided.
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公开(公告)号：EP1934167A2
公开(公告)日：2008-06-25
申请号：EP07810899.0
申请日：2007-07-26
IPC分类号： C07C213/02
CPC分类号： C07C235/34 , C07C2601/14
摘要： The present invention describes processes for the preparation of O-desmethylvenlafaxine and the intermediates cyclohexylbenzylcyanide and tridesmethylvenlafaxine, which may be used as intermediates in preparing O- desmethylvenlafaxine.
摘要翻译： 本发明描述了制备O-去甲基文拉法辛和中间体环己基苄基氰化物和三甲基文拉法辛的方法，其可以用作制备O-去甲基文拉法辛的中间体。
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