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公开(公告)号：EP2694116A2
公开(公告)日：2014-02-12
申请号：EP12767275.6
申请日：2012-04-06
申请人： Board of Regents of the University of Texas System , Alzeca Biosciences, Llc , Board of Regents of the University of Houston System , Texas Children's Hospital
发明人： ANNAPRAGADA, Ananth , ERIKSEN, Jason, L. , TANIFUM, Eric, A. , DASGUPTA, Indrani , COOK, Stephen, C.
CPC分类号： A61K49/1812 , A61K47/6911 , A61K49/0466
摘要： Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer- amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-β plaque deposits characteristic of Alzheimer' s Disease.
摘要翻译： 提供了基于脂质的纳米颗粒组合物。 组合物通常包含脂质亲水性聚合物 - 淀粉样蛋白结合配体缀合物，并且可以是脂质体组合物。 组合物，包括脂质体组合物，可用于淀粉样蛋白的成像和/或治疗。 阿尔茨海默病特征斑块沉积。
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公开(公告)号：EP4103239A1
公开(公告)日：2022-12-21
申请号：EP21753918.8
申请日：2021-02-12
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公开(公告)号：EP3914230A1
公开(公告)日：2021-12-01
申请号：EP20744955.4
申请日：2020-01-24
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公开(公告)号：EP3997244A1
公开(公告)日：2022-05-18
申请号：EP20836078.4
申请日：2020-07-07
发明人： ANNAPRAGADA, Ananth , MU, Qingshan , MEDICI, Carlo
IPC分类号： C12Q1/6811 , C12Q1/6886 , C12N15/115
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公开(公告)号：EP3366313A1
公开(公告)日：2018-08-29
申请号：EP18167725.3
申请日：2012-04-06
申请人： Board Of Regents Of the University Of Texas System , Alzeca Biosciences, Llc , Board of Regents of the University of Houston System , Texas Children's Hospital
发明人： Annapragada, Ananth , Eriksen, Jason, L. , Tanifum, Eric, A. , Dasgupta, Indrani , Cook, Stephen, C.
CPC分类号： A61K49/1812 , A61K47/6911 , A61K49/0466
摘要： Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer-amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-β plaque deposits characteristic of Alzheimer's Disease.
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公开(公告)号：EP2694116B1
公开(公告)日：2018-06-13
申请号：EP12767275.6
申请日：2012-04-06
申请人： Board of Regents of the University of Texas System , Alzeca Biosciences, Llc , Board of Regents of the University of Houston System , Texas Children's Hospital
发明人： ANNAPRAGADA, Ananth , ERIKSEN, Jason, L. , TANIFUM, Eric, A. , DASGUPTA, Indrani , COOK, Stephen, C.
CPC分类号： A61K49/1812 , A61K47/6911 , A61K49/0466
摘要： Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer-amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-β plaque deposits characteristic of Alzheimer's Disease.
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公开(公告)号：EP2694116A4
公开(公告)日：2015-06-03
申请号：EP12767275
申请日：2012-04-06
申请人： UNIV TEXAS , ALZECA BIOSCIENCES LLC , UNIV HOUSTON SYSTEM BOARD OF REGENTS , TEXAS CHILDREN S HOSPITAL
CPC分类号： A61K49/1812 , A61K47/6911 , A61K49/0466
摘要： Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer-amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-β plaque deposits characteristic of Alzheimer's Disease.
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