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    RAPID DETERMINATION OF BLOOD SEDIMENTATION RATE
    2.
    发明公开
    RAPID DETERMINATION OF BLOOD SEDIMENTATION RATE 失效
    混合的液体的小体积的成分的方法，和样本容器

    公开(公告)号：EP0770207A1

    公开(公告)日：1997-05-02

    申请号：EP95924076.0

    申请日：1995-06-26

    Applicant: Bull, Brian S.

    Inventor： Bull, Brian S.

    IPC: G01N15

    CPC classification number: G01N15/05 ,  G11C16/04 ,  G11C2029/5002 ,  G11C2029/5006

    Abstract: An apparatus and method for rapid determination of erythrocyte sedimentation rates for a blood specimen (29) which can be linearly transposed to Westergren sedimentation rates. The method includes the steps of inducing accelerated rouleaux formation in the specimen (29) in an amount sufficient to begin settling at substantially the decantation rate for the specimen. In one embodiment a structure (27) which produces a very thin cross-sectional region (37) of the specimen (29) inside the lumen (23) of a specimen container (21) is provided to accelerate rouleaux formation. In an alternative embodiment (120), accelerated rouleaux formation is accomplished using a centrifuge (122). A third embodiment employs a movable rod (223) mounted inside the specimen tube (221) to induce accelerated rouleaux formation. All embodiments of the process next employ gravity settling the specimen in a near horizontal oriented container (21, 121, 221). Thereafter, the amount of settling occurring is determined. A sealed specimen container (21, 121, 221) which permits thorough mixing of blood in a very small diameter container for use in performing the method also is provided.

    RAPID DETERMINATION OF BLOOD SEDIMENTATION RATE
    4.
    发明公开
    RAPID DETERMINATION OF BLOOD SEDIMENTATION RATE 失效
    血液的快速测定降低车速

    公开(公告)号：EP0770207A4

    公开(公告)日：1999-10-13

    申请号：EP95924076

    申请日：1995-06-26

    Applicant: BULL BRIAN S

    Inventor： BULL BRIAN S

    IPC: G01N15/05

    CPC classification number: G01N15/05 ,  G11C16/04 ,  G11C2029/5002 ,  G11C2029/5006

    Abstract: An apparatus and method for rapid determination of erythrocyte sedimentation rates for a blood specimen (29) which can be linearly transposed to Westergren sedimentation rates. The method includes the steps of inducing accelerated rouleaux formation in the specimen (29) in an amount sufficient to begin settling at substantially the decantation rate for the specimen. In one embodiment a structure (27) which produces a very thin cross-sectional region (37) of the specimen (29) inside the lumen (23) of a specimen container (21) is provided to accelerate rouleaux formation. In an alternative embodiment (120), accelerated rouleaux formation is accomplished using a centrifuge (122). A third embodiment employs a movable rod (223) mounted inside the specimen tube (221) to induce accelerated rouleaux formation. All embodiments of the process next employ gravity settling the specimen in a near horizontal oriented container (21, 121, 221). Thereafter, the amount of settling occurring is determined. A sealed specimen container (21, 121, 221) which permits thorough mixing of blood in a very small diameter container for use in performing the method also is provided.

    Determination of an individual's inflammation index from whole blood fibrinogen and hematocrit or hemoglobin measurements
    6.
    发明公开
    Determination of an individual's inflammation index from whole blood fibrinogen and hematocrit or hemoglobin measurements 失效
    包括生物个体的炎症指标，基于Vollblutfibrinogens的测量和血细胞比容或血红蛋白含量的测定

    公开(公告)号：EP0715170A2

    公开(公告)日：1996-06-05

    申请号：EP95118964.6

    申请日：1995-12-01

    Applicant: Bull, Brian S. ,  Levine, Robert Aaron ,  Wardlaw, Stephen Clark

    Inventor： Bull, Brian S. ,  Levine, Robert Aaron ,  Wardlaw, Stephen Clark

    IPC: G01N33/49 ,  G01N15/05

    CPC classification number: C12Q1/56 ,  G01N33/721 ,  G01N33/86 ,  G01N2333/75 ,  G01N2333/805

    Abstract: Useful information about a subject's level of systemic inflammation is obtained by quantitatively measuring the amount of fibrinogen and the hematocrit and or hemoglobin in the subject's whole blood. The fibrinogen measurement, when combined with an hematocrit or hemoglobin measurement, provides a systemic Inflammation Index value for the donor. The method is not affected by blood variables which are not related to the presence of inflammation, which blood variables are known to invalidate an erythrocyte sedimentation rate, which is the most frequently used blood test for detecting systemic inflammation in humans.

    Abstract translation: 哺乳动物供体全身性炎症的被度确定性从血液样品从供体被吸入到一个透明管（2）contg抗凝的全血供体的样品开采。 细长浮体（4）。 将样品在管离心。 在管中的血样中纤维蛋白原/纤维蛋白的量进行测量。 对于在管中的血液样品血细胞比容血红蛋白或值确定性开采。 I，表示全身性炎症的程度的，通过求解式（i）计算出的数I = A（F）+ B（H）+ C其中，f是样品中测得的纤维蛋白原/纤维蛋白水平; h是样品中的确定性开采血细胞比容血红蛋白或值; 并且a，b和c是经验常数。 的余数值与度相关。 哺乳动物的供体全身性炎症。

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